Enhancing food security amid climate change through rewilding and de novo domestication

Key Points: • Abiotic stress restricts crop production and will increase with climate change, impacting negatively on future food security. • Optimized agronomy, genetic improvement of current germplasm, and diversification of crops under cultivation will contribute to enhanced crop production under future adverse environments. • Development of resistant and high-yielding new crops and varieties may be achieved by de novo domestication of under-utilized crops, wild relatives of crops, and ancestral germplasm