Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine

A - Papers appearing in refereed journals

Noleto-Dias, C., Ward, J. L., Bellisai, A., Lomax, C. and Beale, M. H. 2018. Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine. Fitoterapia. 127 (June), pp. 166-172.

AuthorsNoleto-Dias, C., Ward, J. L., Bellisai, A., Lomax, C. and Beale, M. H.
Abstract

Willow (Salix sp.) is a historically well-known herbal medicine that provided the lead compound (salicin) for the discovery of aspirin, one of the most successful plant derived drugs in human medicine. During a metabolomics screen of 86 Salix species contained in the UK National Willow Collection, we have discovered, isolated and fully characterised a new natural salicinoid – salicin-7-sulfate. This molecule may have important human pharmacological actions that need to be considered in determining the efficacy and safety of willow herbal medicines.

KeywordsSalicin; Willow; Salix; Salicin-7-sulfate
Year of Publication2018
JournalFitoterapia
Journal citation127 (June), pp. 166-172
Digital Object Identifier (DOI)doi:10.1016/j.fitote.2018.02.009
PubMed ID29447984
Open accessPublished as ‘gold’ (paid) open access
FunderEngineering and Physical Sciences Research Council
Biotechnology and Biological Sciences Research Council
Funder project or codeMaximising carbon harvest from perennial crops
TPM - Tailoring Plant Metabolism - Work package 2 (WP2) - Designer Willows: high value phenolic glycosides for health and industry
Ionic Liquid Biorefining of Lignocellulose to Sustainable Polymers
Publisher's version
Copyright license
CC BY
Output statusPublished
Publication dates
Online12 Feb 2018
Publication process dates
Accepted10 Feb 2018
PublisherElsevier Science Bv
Copyright licenseCC BY
ISSN0367-326X

Permalink - https://repository.rothamsted.ac.uk/item/846z3/salicin-7-sulfate-a-new-salicinoid-from-willow-and-implications-for-herbal-medicine

29 total views
42 total downloads
2 views this month
0 downloads this month
Download files as zip