Spontaneous loss and reselection of resistance in extremely resistant Myzus persicae (Sulzer)

A - Papers appearing in refereed journals

Ffrench-Constant, R. H., Devonshire, A. L. and White, Robin P. 1988. Spontaneous loss and reselection of resistance in extremely resistant Myzus persicae (Sulzer). Pesticide Biochemistry and Physiology. 30 (1), pp. 1-10. https://doi.org/10.1016/0048-3575(88)90054-5

AuthorsFfrench-Constant, R. H., Devonshire, A. L. and White, Robin P.
Abstract

Modification of an immunoassay for detection of esterase-4 (E4), the enzyme conferring insecticide resistance in Myzus persicae, enabled further discrimination of extremely high levels of insecticide resistance (R3) from the very high levels (R2) previously characterised by this technique. The modified immunoassay was used to study the rate and pattern of loss of resistance in 10 R3 clones (all possessing an A 1,3 chromosomal translocation) isolated from the field and maintained in population cages. Clones lost resistance at varying rates and one remained stable at a level intermediate between R2 and R3. Loss was catastrophic; high frequencies of susceptible individuals were produced within a clone in the space of one generation without the formation of stable intermediates. However, this was not associated with loss of the chromosomal translocation. Of a number of other R3 clones isolated from the field only one stabilized at an intermediate level of E4 production equivalent to R1. Reselection of resistance in reverted susceptible subclones, by increasing concentrations of insecticide, was due to gradual selection for existing variation in E4 levels which was not apparent in clones of normal karyotype.

Year of Publication1988
JournalPesticide Biochemistry and Physiology
Journal citation30 (1), pp. 1-10
Digital Object Identifier (DOI)https://doi.org/10.1016/0048-3575(88)90054-5
Open accessPublished as non-open access
Funder project or code31
Output statusPublished
Publication dates
Print01 Jan 1988
Publication process dates
Accepted10 Sep 1987
Copyright licensePublisher copyright
PublisherElsevier
ISSN0048-3575

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