On the mapping of QTL by regression of phenotype on marker-type

A - Papers appearing in refereed journals

Whittaker, J. C., Thompson, R. and Visscher, P. M. 1996. On the mapping of QTL by regression of phenotype on marker-type. Heredity. 77, pp. 23-32.

AuthorsWhittaker, J. C., Thompson, R. and Visscher, P. M.
Abstract

We consider the properties of the regression of phenotype on marker-type in Fz and backcross populations. We show that this regression provides exactly the same information about the location and effect of QTL as conventional regression mapping. For certain QTL configurations this information is insufficient to map the QTL. Where the QTL can be mapped, the position and effect of QTL can be estimated directly from the coefficients of the regression of phenotype on marker-type. This requires much less computational effort than conventional regression mapping. Examples are given to illustrate the development of the theory.

KeywordsEcology; Evolutionary Biology; Genetics & Heredity
Year of Publication1996
JournalHeredity
Journal citation77, pp. 23-32
Digital Object Identifier (DOI)doi:10.1038/hdy.1996.104
Open accessPublished as bronze (free) open access
Funder project or code207
445
Project: 141433
Publisher's version
Output statusPublished
Publication dates
Print01 Jul 1996
Copyright licensePublisher copyright
PublisherWiley
Nature Publishing Group
ISSN0018-067X

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