A genomics approach to crop pest and disease research

A - Papers appearing in refereed journals

Keon, J. P. R., Curtis, R. H. C., Cabrera, H. L. and Hargreaves, J. A. 2003. A genomics approach to crop pest and disease research. Pest Management Science. 59 (2), pp. 143-148.

AuthorsKeon, J. P. R., Curtis, R. H. C., Cabrera, H. L. and Hargreaves, J. A.

Genome-wide analyses of gene function and gene expression are beginning to yield valuable information in many areas of biological research, and these genomic tools are now being applied to crop pest and disease research. DNA sequencing of cDNA libraries to generate sets of expressed sequence tags (ESTs) are allowing gene compendiums for crop diseases to be compiled. Annotation of such data collections is also providing a wealth of functional information about gene products through similarities to proteins with known function. The next phase of the functional genomics era will be to employ large-scale techniques to knock out or silence genes in order to synthesize gene-specific mutants for phenotypic analysis and to use micro-array methodology to analyze global gene expression, protein turnover and protein processing during the processes of parasitism and colonization. Application of these technologies promises to accelerate the pace that biological information relevant to crop protection accrues. The ability of researchers to assimilate this information into complex models and workable hypotheses is, thus, set to revolutionize the way we study pests and diseases of crop plants. (C) 2003 Society of Chemical Industry.

KeywordsAgronomy; Entomology
Year of Publication2003
JournalPest Management Science
Journal citation59 (2), pp. 143-148
Digital Object Identifier (DOI)doi:10.1002/ps.571
PubMed ID12587867
Open accessPublished as non-open access
Funder project or code421
Output statusPublished
Publication dates
Online07 Jan 2003
Publication process dates
Accepted06 Jan 2002
Copyright licensePublisher copyright

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