A - Papers appearing in refereed journals
Gunning, R. V., Moores, G. D., Jewess, P., Boyes, A. L., Devonshire, A. L. and Khambay, B. P. S. 2007. Use of pyrethroid analogues to identify key structural features for enhanced esterase resistance in Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae). Pest Management Science. 63 (6), pp. 569-575.
|Authors||Gunning, R. V., Moores, G. D., Jewess, P., Boyes, A. L., Devonshire, A. L. and Khambay, B. P. S.|
It has been reported previously that the major resistance mechanism to pyrethroid insecticides by the cotton bollworm Helicoverpa armigera (Hubner) in Australia is a consequence of overproduction of esterase isoenzymes. This paper reports structure-activity relationships that support such a view, based on in vivo bioassays conducted with a range of pyrethroid structures containing a variety of acid and alcohol moieties and the correlation with in vitro esterase inhibition assays against the same structures, and identifies the critical regions of the molecule with regard to esterase inhibition, and hence resistance. The implications of this work in terms of possible resistance management are evaluated and discussed. (c) 2007 Society of Chemical Industry.
|Year of Publication||2007|
|Journal||Pest Management Science|
|Journal citation||63 (6), pp. 569-575|
|Digital Object Identifier (DOI)||doi:10.1002/ps.1377|
|Open access||Published as non-open access|
|Funder project or code||Centre for Sustainable Pest and Disease Management (PDM)|
Permalink - https://repository.rothamsted.ac.uk/item/89wvx/use-of-pyrethroid-analogues-to-identify-key-structural-features-for-enhanced-esterase-resistance-in-helicoverpa-armigera-hubner-lepidoptera-noctuidae