Adopting an integrative systems biology approach to study root growth and development

Bennett, M., French, A., Hodgman, C., Hedden, P., Holman, T., Middleton, A., King, J., Owen, M., Pridmore, T., Swarup, R., Thomas, S. G., Ubeda-Tomas, S. and Wilson, M. 2008. Adopting an integrative systems biology approach to study root growth and development. https://doi.org/10.1016/j.cbpa.2008.04.022

Related outputs

Gibberellin function in root growth and development

B - Book chapters etc edited externally

Hedden, P. 2024. Gibberellin function in root growth and development. in: Beekcman, T. and Ashel, A. (ed.) Plant Roots – The Hidden Half Taylor & Francis.

At the crossroads: strigolactones mediate changes in cytokinin synthesis and signalling in response to nitrogen limitation

A - Papers appearing in refereed journals

Sigalas, P., Bennett, T., Buchner, P. H., Thomas, S. G., Jamois, F., Arkoun, M., Yvin, J.-C., Bennett, M.J. and Hawkesford, M. J. 2024. At the crossroads: strigolactones mediate changes in cytokinin synthesis and signalling in response to nitrogen limitation. The Plant Journal. https://doi.org/10.1111/tpj.16976

Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype

A - Papers appearing in refereed journals

Ndreca, B., Huttly, A. K., Bibi, S., Bayon, C., Lund, G., Ham, J., Alarcon-Reverte, R., Addy, J., Tarkowská, D., Pearce, S., Hedden, P., Thomas, S. G. and Phillips, A. L. 2024. Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype. BMC Plant Biology. 24, p. 384. https://doi.org/10.1186/s12870-024-05098-1

Highlights in gibberellin research A tale of the dwarf and the slender

A - Papers appearing in refereed journals

Shani, E., Hedden, P. and Sun, T. 2024. Highlights in gibberellin research A tale of the dwarf and the slender . Plant Physiology. p. kiae044. https://doi.org/10.1093/plphys/kiae044

Environmental regulation of male fertility is mediated through Arabidopsis transcription factors bHLH89, 91, and 10

A - Papers appearing in refereed journals

Robson, J. K., Tidy, A. C., Thomas, S. G. and Wilson, Z. A. 2023. Environmental regulation of male fertility is mediated through Arabidopsis transcription factors bHLH89, 91, and 10 . Journal of Experimental Botany. p. erad480. https://doi.org/10.1093/jxb/erad480

Nutritional and tissue-specific regulation of cytochrome P450 CYP711A MAX1 homologues and strigolactone biosynthesis in wheat

A - Papers appearing in refereed journals

Sigalas, P., Buchner, P. H., Thomas, S. G., Jamois, F., Arkourn, M., Yvin, J.- C., Bennett, M. J. and Hawkesford, M. J. 2023. Nutritional and tissue-specific regulation of cytochrome P450 CYP711A MAX1 homologues and strigolactone biosynthesis in wheat. Journal of Experimental Botany. 74 (6), pp. 1890-1910. https://doi.org/10.1093/jxb/erad008

Changes in the concentrations and transcripts for gibberellins and other hormones in a growing leaf and roots of wheat seedlings in response to water restriction

A - Papers appearing in refereed journals

Ptoskova, K., Szecowka, M., Jaworek, P., Tarkowska, D., Petrik, I., Pavlovic, I., Novak, O., Thomas, S. G., Phillips, A. L. and Hedden, P. 2022. Changes in the concentrations and transcripts for gibberellins and other hormones in a growing leaf and roots of wheat seedlings in response to water restriction. BMC Plant Biology. 22 (1), p. 284. https://doi.org/10.1186/s12870-022-03667-w

Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins

A - Papers appearing in refereed journals

Camut, L., Gallova, B., Jilli, L., Sirlin-Josserand, M., Carrera, E., Sakvarelidze-Achard, L., Ruffel, S., Krouk, G., Thomas, S. G., Hedden, P., Phillips, A. L., Daviere, J-M. and Achard, P. 2021. Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins. Current Biology. 31 (22), pp. 4971-4982. https://doi.org/10.1016/j.cub.2021.09.024

N-terminal truncated RHT-1 proteins generated by translational reinitiation cause semi-dwarfing of wheat Green Revolution alleles

A - Papers appearing in refereed journals

Thomas, S. G., Van De Velde, K., Heyse, F., Kaspar, R., Van Der Straeten, D. and Rohde, A. 2021. N-terminal truncated RHT-1 proteins generated by translational reinitiation cause semi-dwarfing of wheat Green Revolution alleles. Molecular Plant. 14 (1), pp. 1-9. https://doi.org/10.1016/j.molp.2021.01.002

Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply

A - Papers appearing in refereed journals

Wang, X., Shen, J., Hedden, P., Phillips, A. L., Thomas, S. G., Ge, Y., Ashton, R. W. and Whalley, W. R. 2021. Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply. Soil & Tillage Research. 205, p. 104754. https://doi.org/10.1016/j.still.2020.104754

The Current Status of Research on Gibberellin Biosynthesis

A - Papers appearing in refereed journals

Hedden, P. 2020. The Current Status of Research on Gibberellin Biosynthesis. Plant and cell physiology. 6 (11), pp. 1832-1849. https://doi.org/10.1093/pcp/pcaa092

Mapping sites of gibberellin biosynthesis in the Arabidopsis root tip

A - Papers appearing in refereed journals

Barker, R., Garcia, M. N. F., Powers, S. J., Vaughan, S., Bennett, M. J., Phillips, A. L., Thomas, S. G. and Hedden, P. 2020. Mapping sites of gibberellin biosynthesis in the Arabidopsis root tip. New Phytologist. https://doi.org/10.1111/NPH.16967

A novel gibberellin promotes seedling establishment

A - Papers appearing in refereed journals

Hedden, P. 2019. A novel gibberellin promotes seedling establishment. Nature Plants. 5 (May), p. 459–460. https://doi.org/10.1038/s41477-019-0427-7

The early inflorescence of Arabidopsis thaliana demonstrates positional effects in floral organ growth and meristem patterning

A - Papers appearing in refereed journals

Plackett, A. R. G., Powers, S. J., Phillips, A. L., Wilson, Z. A., Hedden, P. and Thomas, S. G. 2018. The early inflorescence of Arabidopsis thaliana demonstrates positional effects in floral organ growth and meristem patterning. Plant Reproduction. 31 (2), pp. 171-191. https://doi.org/10.1007/s00497-017-0320-3

Novel Rht-1 dwarfing genes: tools for wheat breeding and dissecting the function of DELLA proteins

A - Papers appearing in refereed journals

Thomas, S. G. 2017. Novel Rht-1 dwarfing genes: tools for wheat breeding and dissecting the function of DELLA proteins. Journal of Experimental Botany. 68 (3), pp. 354-358. https://doi.org/10.1093/jxb/erw509

Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution

A - Papers appearing in refereed journals

Nett, R. S., Montanares, M., Marcassa, A., Lu, X., Nagel, R., Charles, T. C., Hedden, P., Rojas, M. C. and Peters, R. J. 2017. Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution. Nature Chemical Biology. 13 (1), pp. 69-74. https://doi.org/10.1038/nchembio.2232

O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis

A - Papers appearing in refereed journals

Zentella, R., Hu, J. H., Hsieh, W. P., Matsumoto, P. A., Dawdy, A., Barnhill, B., Oldenhof, H., Hartweck, L. M., Maitra, S., Thomas, S. G., Cockrell, S., Boyce, M., Shabanowitz, J., Hunt, D. F., Olszewski, N. E. and Sun, T. P. 2016. O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis. Genes & Development. 30 (2), pp. 164-176. https://doi.org/10.1101/gad.270587.115

Gibberellin biosynthesis in higher plants

B - Book chapters etc edited externally

Hedden, P. 2016. Gibberellin biosynthesis in higher plants. in: Hedden, P. and Thomas, S. G. (ed.) Annual Plant Reviews, Volume 49: Gibberellins, The (Chapter 2) Wiley.

Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis

A - Papers appearing in refereed journals

Porco, S., Pencik, A., Rashed, A., Voss, U., Casanova-Saez, R., Bishopp, A., Golebiowska, A., Bhosale, R., Swarup, R., Swarup, K., Penakova, P., Novak, O., Staswick, P., Hedden, P., Phillips, A. L., Vissenberg, K., Bennett, M. J. and Ljung, K. 2016. Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis. Proceedings of the National Academy of Sciences. 113 (39), pp. 11016-11021. https://doi.org/10.1073/pnas.1604375113

Deep roots and soil structure

A - Papers appearing in refereed journals

Gao, W., Hodgkinson, L., Jin, K., Watts, C. W., Ashton, R. W., Shen, J., Ren, T., Dodd, I. C., Binley, A., Phillips, A. L., Hedden, P., Hawkesford, M. J. and Whalley, W. R. 2016. Deep roots and soil structure. Plant, Cell and Environment. 39 (8), pp. 1662-1668. https://doi.org/10.1111/pce.12684

The gibberellin precursor GA12 acts as a long-distance growth signal in Arabidopsis

A - Papers appearing in refereed journals

Regnault, T., Daviere, J-M., Wild, M., Sakvarelidze-Achard, L., Heintz, D., Carrera Bergua, E., Lopez Diaz, I., Gong, F., Hedden, P. and Achard, P. 2015. The gibberellin precursor GA12 acts as a long-distance growth signal in Arabidopsis. Nature Plants. 1, p. 15073. https://doi.org/10.1038/nplants.2015.73

A conserved cytochrome P450 evolved in seed plants regulates flower maturation

A - Papers appearing in refereed journals

Liu, Z., Boachon, B., Lugan, R., Tavares, R., Erhardt, M., Mutterer, J., Demais, V., Pateyron, S., Brunaud, V., Ohnishi, T., Pencik, A., Achard, P., Gong, F., Hedden, P., Werck-Reichhart, D. and Renault, H. 2015. A conserved cytochrome P450 evolved in seed plants regulates flower maturation. Molecular Plant. 8, pp. 1751-1765. https://doi.org/10.1016/j.molp.2015.09.002

Gibberellin metabolism

B - Book chapters etc edited externally

Hedden, P. and Phillips, A. L. 2015. Gibberellin metabolism. in: Hausinger, R. P. and Schofield, C. J. (ed.) 2-Oxoglutarate-dependent oxygenases Royal Society of Chemistry (RSC), Cambridge. pp. 367-384

A century of gibberellin research

A - Papers appearing in refereed journals

Hedden, P. and Sponsel, V. 2015. A century of gibberellin research. Journal of Plant Growth Regulation. 34, pp. 740-760. https://doi.org/10.1007/s00344-015-9546-1

Genome wide binding site analysis reveals transcriptional coactivation of cytokinin-responsive genes by DELLA proteins

A - Papers appearing in refereed journals

Marin-De La Rosa, N., Pfeiffer, A., Hill, K., Locascio, A., Bhalerao, R. P., Miskolczi, P., Gronlund, A. L., Wanchoo-Kohli, A., Thomas, S. G., Bennett, M. J., Lohmann, J. U., Blazquez, M. A. and Alabadi, D. 2015. Genome wide binding site analysis reveals transcriptional coactivation of cytokinin-responsive genes by DELLA proteins. PLOS Genetics. 11, p. e1005337. https://doi.org/10.1371/journal.pgen.1005337

Heterologous expression and transcript analysis of gibberellin biosynthetic genes of grasses reveals novel functionality in the GA3ox family

A - Papers appearing in refereed journals

Pearce, S., Huttly, A. K., Prosser, I. M., Li, Y-D., Vaughan, S. P., Gallova, B., Patil, A., Coghill, J. A., Dubcovsky, J., Hedden, P. and Phillips, A. L. 2015. Heterologous expression and transcript analysis of gibberellin biosynthetic genes of grasses reveals novel functionality in the GA3ox family. BMC Plant Biology. 15, p. 130. https://doi.org/10.1186/s12870-015-0520-7

Pre-maturity alpha-amylase in wheat: the role of abscisic acid and gibberellins

A - Papers appearing in refereed journals

Kondhare, K. R., Farrell, A. D., Kettlewell, P. S., Hedden, P. and Monaghan, J. M. 2015. Pre-maturity alpha-amylase in wheat: the role of abscisic acid and gibberellins. Journal of Cereal Science. 63, pp. 95-108. https://doi.org/10.1016/j.jcs.2015.03.004

Jake MacMillan: A pioneering chemist in plant biology

A - Papers appearing in refereed journals

Hedden, P. and Beale, M. H. 2014. Jake MacMillan: A pioneering chemist in plant biology. Proceedings of the National Academy of Sciences. 111 (41), pp. 14641-14642. https://doi.org/10.1073/pnas.1414365111

Use of the hormone-biosynthesis inhibitors fluridone and paclobutrazol to determine the effects of altered abscisic acid and gibberellin levels on pre-maturity alpha-amylase formation in wheat grains

A - Papers appearing in refereed journals

Kondhare, K. R., Hedden, P., Kettlewell, P. S., Farrell, A. D. and Monaghan, J. M. 2014. Use of the hormone-biosynthesis inhibitors fluridone and paclobutrazol to determine the effects of altered abscisic acid and gibberellin levels on pre-maturity alpha-amylase formation in wheat grains. Journal of Cereal Science. 60, pp. 210-216. https://doi.org/10.1016/j.jcs.2014.03.001

Quantifying the impact of exogenous abscisic acid and gibberellins on pre-maturity alpha-amylase formation in developing wheat grains

A - Papers appearing in refereed journals

Kondhare, K. R., Hedden, P., Kettlewell, P. S., Farrell, A. D. and Monaghan, J. M. 2014. Quantifying the impact of exogenous abscisic acid and gibberellins on pre-maturity alpha-amylase formation in developing wheat grains. Scientific Reports. 4, p. 5355. https://doi.org/10.1038/srep05355

Gibberellin oxidase activities in Bradyrhizobium japonicum bacteroids

A - Papers appearing in refereed journals

Mendez, C., Baginsky, C., Hedden, P., Gong, F., Caru, M. and Rojas, M. C. 2014. Gibberellin oxidase activities in Bradyrhizobium japonicum bacteroids. Phytochemistry. 98, pp. 101-109. https://doi.org/10.1016/j.phytochem.2013.11.013

Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin

A - Papers appearing in refereed journals

Conti, L., Nelis, S., Zhang, C., Woodcock, A., Swarup, R., Galbiati, M., Tonelli, C., Napier, R., Hedden, P., Bennett, M. and Sadanandom, A. 2014. Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin. Developmental Cell. 28, pp. 102-110. https://doi.org/10.1016/j.devcel.2013.12.004

DELLA activity is required for successful pollen development in the Columbia ecotype of Arabidopsis

A - Papers appearing in refereed journals

Plackett, A. R. G., Ferguson, A. C., Powers, S. J., Wanchoo-Kohli, A., Phillips, A. L., Wilson, Z. A., Hedden, P. and Thomas, S. G. 2014. DELLA activity is required for successful pollen development in the Columbia ecotype of Arabidopsis. New Phytologist. 201 (3), pp. 825-836. https://doi.org/10.1111/nph.12571

The role of gibberellin signalling in plant responses to abiotic stress

A - Papers appearing in refereed journals

Colebrook, E. H., Thomas, S. G., Phillips, A. L. and Hedden, P. 2014. The role of gibberellin signalling in plant responses to abiotic stress. Journal Of Experimental Biology. 217, pp. 67-75. https://doi.org/10.1242/jeb.089938

Isolation, characterization, and expression of the Ricesd-1 (GA20ox) Gene Ortholog in Eragrostis tef

A - Papers appearing in refereed journals

Gebre, E., Hedden, P., Kunert, K. and Schlter, U. 2013. Isolation, characterization, and expression of the Ricesd-1 (GA20ox) Gene Ortholog in Eragrostis tef. Journal of Crop Improvement. 27 (5), pp. 507-527. https://doi.org/10.1080/15427528.2013.797945

The role of sensitivity to abscisic acid and gibberellin in pre-maturity alpha-amylase formation in wheat grains

A - Papers appearing in refereed journals

Kondhare, K. R., Kettlewell, P. S., Farrell, A. D., Hedden, P. and Monaghan, J. M. 2013. The role of sensitivity to abscisic acid and gibberellin in pre-maturity alpha-amylase formation in wheat grains. Journal of Cereal Science. 58, pp. 472-478. https://doi.org/10.1016/j.jcs.2013.09.009

The involvement of gibberellin signalling in the effect of soil resistance to root penetration on leaf elongation and tiller number in wheat

A - Papers appearing in refereed journals

Coelho Filho, M. A., Colebrook, E. H., Lloyd, D. P. A., Webster, C. P., Mooney, S. J., Phillips, A. L., Hedden, P. and Whalley, W. R. 2013. The involvement of gibberellin signalling in the effect of soil resistance to root penetration on leaf elongation and tiller number in wheat. Plant and Soil. 371, pp. 81-94. https://doi.org/10.1007/s11104-013-1662-8

Analysis of gibberellins as free acids by ultra performance liquid chromatography-tandem mass spectrometry

A - Papers appearing in refereed journals

Urbanova, T., Tarkowska, D., Novak, O., Hedden, P. and Strnad, M. 2013. Analysis of gibberellins as free acids by ultra performance liquid chromatography-tandem mass spectrometry. Talanta. 112, pp. 85-94. https://doi.org/10.1016/j.talanta.2013.03.068

Transcriptional changes of the root-knot nematode Meloidogyne incognita in response to Arabidopsis thaliana root signals

A - Papers appearing in refereed journals

Teillet, A., Dybal, K., Kerry, B. R., Miller, A. J., Curtis, R. H. C. and Hedden, P. 2013. Transcriptional changes of the root-knot nematode Meloidogyne incognita in response to Arabidopsis thaliana root signals. PLOS ONE. 8, p. e61259. https://doi.org/10.1371/journal.pone.0061259

Development of new quantitative physiological and molecular breeding parameters based on the sugar-beet vernalization intensity model

A - Papers appearing in refereed journals

Chiurugwi, T., Holmes, H. F., Qi, A., Chia, T. Y. P., Hedden, P. and Mutasa-Göttgens, E. S. 2013. Development of new quantitative physiological and molecular breeding parameters based on the sugar-beet vernalization intensity model. The Journal of Agricultural Science. 151, pp. 492-505. https://doi.org/10.1017/S0021859612000573

Effects of exogenous abscisic acid and gibberellic acid on pre-maturity alpha-amylase formation in wheat grains

A - Papers appearing in refereed journals

Kondhare, K., Kettlewell, P., Farrell, A., Hedden, P. and Monaghan, J. 2012. Effects of exogenous abscisic acid and gibberellic acid on pre-maturity alpha-amylase formation in wheat grains. Euphytica. 188 (1), pp. 51-60. https://doi.org/10.1007/s10681-012-0706-0

Molecular mechanism for the interaction between gibberellin and brassinosteroid signaling pathways in Arabidopsis

A - Papers appearing in refereed journals

Gallego-Bartolome, J., Minguet, E. G., Grau-Enguix, F., Abbas, M., Locascio, A., Thomas, S. G., Alabadi, D. and Blazquez, M. A. 2012. Molecular mechanism for the interaction between gibberellin and brassinosteroid signaling pathways in Arabidopsis. Proceedings of the National Academy of Sciences. 109, pp. 13446-13451. https://doi.org/10.1073/pnas.1119992109

Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum

A - Papers appearing in refereed journals

Studt, L., Troncoso, C., Gong, F., Hedden, P., Toomajian, C., Leslie, J. F., Humpf, H-U., Rojas, M. C. and Tudzynski, B. 2012. Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum. Fungal Genetics and Biology. 49, pp. 567-577. https://doi.org/10.1016/j.fgb.2012.05.005

A short history of gibberellin biosynthesis: a very personal perspective

A - Papers appearing in refereed journals

Hedden, P. 2012. A short history of gibberellin biosynthesis: a very personal perspective. Regulation of Plant Growth and Development. 47 (1), pp. 52-57.

Gibberellin biosynthesis inhibitors help control plant height for improving lodging resistance in E. Tef (Eragrostis tef)

A - Papers appearing in refereed journals

Gebre, E., Schluter, U., Hedden, P. and Kunert, K. 2012. Gibberellin biosynthesis inhibitors help control plant height for improving lodging resistance in E. Tef (Eragrostis tef). Journal of Crop Improvement. 26, pp. 375-388. https://doi.org/10.1080/15427528.2011.646056

Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling

A - Papers appearing in refereed journals

Middleton, A. M., Ubeda-Tomas, S., Griffiths, J., Holman, T., Hedden, P., Thomas, S. G., Phillips, A. L., Holdsworthy, M. J., Bennett, M. J., King, J. R. and Owen, M. R. 2012. Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling. Proceedings of the National Academy of Sciences. 109, pp. 7571-7576. https://doi.org/10.1073/pnas.1113666109

Genetic and physiological analysis of Rht8 in bread wheat: an alternative source of semi-dwarfism with a reduced sensitivity to brassinosteroids

A - Papers appearing in refereed journals

Gasperini, D., Greenland, A., Hedden, P., Dreos, R., Harwood, W. and Griffiths, S. 2012. Genetic and physiological analysis of Rht8 in bread wheat: an alternative source of semi-dwarfism with a reduced sensitivity to brassinosteroids. Journal of Experimental Botany. 63, pp. 4419-4436. https://doi.org/10.1093/jxb/ers138

The characterization of transgenic tomato overexpressing gibberellin 20-oxidase reveals induction of the parthenocarpic fruit growth, higher yield and alteration of the gibberellin biosynthetic pathway

A - Papers appearing in refereed journals

Garcia-Hurtado, N., Carrera, E., Ruiz-Rivero, O., Lopez-Gresa, M. P., Hedden, P., Gong, F. and Garcia-Martinez, J. L. 2012. The characterization of transgenic tomato overexpressing gibberellin 20-oxidase reveals induction of the parthenocarpic fruit growth, higher yield and alteration of the gibberellin biosynthetic pathway. Journal of Experimental Botany. 63, pp. 5803-5813. https://doi.org/10.1093/jxb/ers229

Leaf-induced gibberellin signaling is essential for internode elongation, cambial activity and fiber differentiation in tobacco stems

A - Papers appearing in refereed journals

Dayan, J., Voronin, N., Gong, F., Sun, T-P., Hedden, P., Fromm, H. and Aloni, R. 2012. Leaf-induced gibberellin signaling is essential for internode elongation, cambial activity and fiber differentiation in tobacco stems. The Plant Cell. 24, pp. 66-79. https://doi.org/10.1105/tpc.111.093096

Characterization of the fungal gibberellin desaturase as a 2-oxoglutarate-dependent dioxygenase and its utilization for enhancing plant growth

A - Papers appearing in refereed journals

Bhattacharya, A., Kourmpetli, S., Ward, D. A., Thomas, S. G., Gong, F., Powers, S. J., Carrera, E., Taylor, B., Nunez De Caceres Gonzalez, F., Tudzynski, B., Phillips, A. L., Davey, M. R. and Hedden, P. 2012. Characterization of the fungal gibberellin desaturase as a 2-oxoglutarate-dependent dioxygenase and its utilization for enhancing plant growth. Plant Physiology. 160, pp. 837-845. https://doi.org/10.1104/pp.112.201756

A new RNASeq-based reference transcriptome for sugar beet and its application in transcriptome-scale analysis of vernalization and gibberellin responses

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S., Joshi, A., Holmes, H. F., Hedden, P. and Gottgens, B. 2012. A new RNASeq-based reference transcriptome for sugar beet and its application in transcriptome-scale analysis of vernalization and gibberellin responses. BMC Genomics. 13, p. 99. https://doi.org/10.1186/1471-2164-13-99

Analysis of the developmental roles of the Arabidopsis gibberellin 20-oxidases demonstrates that GA20ox1, -2 and -3 are the dominant paralogs

A - Papers appearing in refereed journals

Plackett, A. R. G., Powers, S. J., Fernandez-Garcia, N., Urbanova, T., Takebayashi, Y., Seo, M., Jikumaru, Y., Benlloch, R., Nilsson, O., Ruiz-Rivero, O., Phillips, A. L., Wilson, Z. A., Thomas, S. G. and Hedden, P. 2012. Analysis of the developmental roles of the Arabidopsis gibberellin 20-oxidases demonstrates that GA20ox1, -2 and -3 are the dominant paralogs. The Plant Cell. 24, pp. 941-960. https://doi.org/10.1105/tpc.111.095109

Gibberellin biosynthesis and its regulation

A - Papers appearing in refereed journals

Hedden, P. and Thomas, S. G. 2012. Gibberellin biosynthesis and its regulation. Biochemical Journal. 444, pp. 11-25. https://doi.org/10.1042/BJ20120245

Engineering gibberellin metabolism in Solanum nigrum L. by ectopic expression of gibberellin oxidase genes

A - Papers appearing in refereed journals

Bhattacharya, A., Ward, D. A., Hedden, P., Phillips, A. L., Power, J. B. and Davey, M. R. 2012. Engineering gibberellin metabolism in Solanum nigrum L. by ectopic expression of gibberellin oxidase genes. Plant Cell Reports. 31, pp. 945-953. https://doi.org/10.1007/s00299-011-1214-8

The role of gibberellin in determining wheat grain size and quality

C2 - Non-edited contributions to conferences

Vaughan, S. P., Wanchoo-Kohli, A., Patil, A., Huttly, A. K., Phillips, A. L. and Hedden, P. 2011. The role of gibberellin in determining wheat grain size and quality. ABRATES.

The role of gibberellin in determining wheat grain size and quality

C1 - Edited contributions to conferences/learned societies

Vaughan, S. P., Wanchoo-Kohli, A., Patil, A., Huttly, A. K., Phillips, A. L. and Hedden, P. 2011. The role of gibberellin in determining wheat grain size and quality. GM Crops: from Basic Research to Application. Aspects of Applied Biology 110 . Association of Applied Biologists (AAB) Wellesbourne Warwick . pp. 14

Gibberellins - terpenoid plant hormones: biological importance and chemical analysis

A - Papers appearing in refereed journals

Urbanova, T., Tarkowska, D., Strnad, M. and Hedden, P. 2011. Gibberellins - terpenoid plant hormones: biological importance and chemical analysis. Collection of Czechoslovak Chemical Communications. 76, pp. 1669-1686. https://doi.org/10.1135/cccc2011098

Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat

A - Papers appearing in refereed journals

Pearce, S., Saville, R., Vaughan, S. P., Chandler, P. M., Wilhelm, E. P., Sparks, C. A., Al-Kaff, N., Korolev, A., Boulton, M. I., Phillips, A. L., Hedden, P., Nicholson, P. and Thomas, S. G. 2011. Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat. Plant Physiology. 157, pp. 1820-1831. https://doi.org/10.1104/pp.111.183657

The transcription factor ABI4 is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis

A - Papers appearing in refereed journals

Kerchev, P. I., Pellny, T. K., Vivancos, P. D., Kiddle, G., Hedden, P., Driscoll, S. P., Vanacker, H., Verrier, P. J., Hancock, R. D. and Foyer, C. H. 2011. The transcription factor ABI4 is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis. The Plant Cell. 23, pp. 3319-3334. https://doi.org/10.1105/tpc.111.090100

Heterosis in rice seedlings: its relationship to gibberellin content and expression of gibberellin metabolism and signaling genes

A - Papers appearing in refereed journals

Ma, Q., Hedden, P. and Zhang, Q. 2011. Heterosis in rice seedlings: its relationship to gibberellin content and expression of gibberellin metabolism and signaling genes. Plant Physiology. 156, pp. 1905-1920. https://doi.org/10.1104/pp.111.178046

Gibberellin control of stamen development: a fertile field

A - Papers appearing in refereed journals

Plackett, A. R. G., Thomas, S. G., Wilson, Z. A. and Hedden, P. 2011. Gibberellin control of stamen development: a fertile field. Trends in Plant Science. 16, pp. 568-578. https://doi.org/10.1016/j.tplants.2011.06.007

Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin

A - Papers appearing in refereed journals

Hartmann, A., Senning, M., Hedden, P., Sonnewald, U. and Sonnewald, S. 2011. Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin. Plant Physiology. 155, pp. 776-796. https://doi.org/10.1104/pp.110.168252

Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress

A - Papers appearing in refereed journals

Fernandez-Garcia, N., Hernandez, M., Casado-Vela, J., Bru, R., Elortza, F., Hedden, P. and Olmos, E. 2011. Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress. Plant, Cell and Environment. 34 (5), pp. 821-836. https://doi.org/10.1111/j.1365-3040.2011.02285.x

Gibberellin signalling - new opportunities for crop management

G - Articles in popular magazines and other technical publications

Hedden, P., Rademacher, W. and Phillips, A. L. 2010. Gibberellin signalling - new opportunities for crop management. Outlooks on Pest Management. 21 (6), pp. 268-273. https://doi.org/10.1564/21Dec05

Gibberellin 3-oxidases in developing embryos of the southern wild cucumber, Marah macrocarpus

A - Papers appearing in refereed journals

Ward, D. A., Macmillan, J., Gong, F., Phillips, A. L. and Hedden, P. 2010. Gibberellin 3-oxidases in developing embryos of the southern wild cucumber, Marah macrocarpus. Phytochemistry. 71, pp. 2010-2018. https://doi.org/10.1016/j.phytochem.2010.09.015

Bolting and flowering control in sugar beet: relationships and effects of gibberellin, the bolting gene B and vernalization

A - Papers appearing in refereed journals

Mutasa-Gottgens, E. S., Qi, A., Zhang, W., Schulze-Buxloh, G., Jennings, A., Hohmann, U., Muller, A. E. and Hedden, P. 2010. Bolting and flowering control in sugar beet: relationships and effects of gibberellin, the bolting gene B and vernalization. AoB Plants. 2010, p. plq012. https://doi.org/10.1093/aobpla/plq012

Gibberellin biosynthesis and gibberellin oxidase activities in Fusarium sacchari, Fusarium konzum and Fusarium subglutinans strains

A - Papers appearing in refereed journals

Troncoso, C., Gonzalez, X., Bomke, C., Tudzynski, B., Gong, F., Hedden, P. and Rojas, M. C. 2010. Gibberellin biosynthesis and gibberellin oxidase activities in Fusarium sacchari, Fusarium konzum and Fusarium subglutinans strains. Phytochemistry. 71, pp. 1322-1331. https://doi.org/10.1016/j.phytochem.2010.05.006

Abscisic acid levels in tomato ovaries are regulated by LeNCED1 and SlCYP707A1

A - Papers appearing in refereed journals

Nitsch, L. M. C., Oplaat, C., Feron, R., Ma, Q., Wolters-Arts, M., Hedden, P., Mariani, C. and Vriezen, W. H. 2009. Abscisic acid levels in tomato ovaries are regulated by LeNCED1 and SlCYP707A1. Planta. 229, pp. 1335-1346. https://doi.org/10.1007/s00425-009-0913-7

Gibberellin as a factor in floral regulatory networks

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S. and Hedden, P. 2009. Gibberellin as a factor in floral regulatory networks. Journal of Experimental Botany. 60, pp. 1979-1989. https://doi.org/10.1093/jxb/erp040

Modification of gibberellin signalling (metabolism and signal transduction) in sugar beet: analysis of potential targets for crop improvement

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S., Qi, A., Mathews, A. M., Thomas, S. G., Phillips, A. L. and Hedden, P. 2009. Modification of gibberellin signalling (metabolism and signal transduction) in sugar beet: analysis of potential targets for crop improvement. Transgenic Research. 18, pp. 301-308. https://doi.org/10.1007/s11248-008-9211-6

Loss of gibberellin production in Fusarium verticillioides (Gibberella fujikuroi MP-A) is due to a deletion in the gibberellic acid gene cluster

A - Papers appearing in refereed journals

Bomke, C., Rojas, M. C., Hedden, P. and Tudzynski, B. 2008. Loss of gibberellin production in Fusarium verticillioides (Gibberella fujikuroi MP-A) is due to a deletion in the gibberellic acid gene cluster. Applied and Environmental Microbiology. 74, pp. 7790-7801. https://doi.org/10.1128/AEM.01819-08

Gibberellins close the lid

G - Articles in popular magazines and other technical publications

Hedden, P. 2008. Gibberellins close the lid. Nature. 456 (27 November), pp. 455-456. https://doi.org/10.1038/456455a

Genetic analysis reveals that C19-GA 2-oxidation is a major gibberellin inactivation pathway in Arabidopsis

A - Papers appearing in refereed journals

Rieu, I., Eriksson, S., Powers, S. J., Gong, F., Griffiths, J., Woolley, L., Benlloch, R., Nilsson, O., Thomas, S. G., Hedden, P. and Phillips, A. L. 2008. Genetic analysis reveals that C19-GA 2-oxidation is a major gibberellin inactivation pathway in Arabidopsis. The Plant Cell. 20, pp. 2420-2436. https://doi.org/10.1105/tpc.108.058818

Ectopic expression of soybean leghemoglobin in chloroplasts impairs gibberellin biosynthesis and induces dwarfism in transgenic potato plants

A - Papers appearing in refereed journals

Bonna, A. L., Chaparro-Giraldo, A., Appezzato-Da-Gloria, B., Hedden, P. and Silva-Filho, M. C. 2008. Ectopic expression of soybean leghemoglobin in chloroplasts impairs gibberellin biosynthesis and induces dwarfism in transgenic potato plants. Molecular Breeding. 22, pp. 613-618. https://doi.org/10.1007/s11032-008-9203-5

Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant

A - Papers appearing in refereed journals

De Grauwe, L., Chaerle, L., Dugardeyn, J., Decat, J., Rieu, I., Vriezen, W. H., Moritz, T., Beemster, G. T. S., Phillips, A. L., Harberd, N. P., Hedden, P. and Van Der Straeten, D. 2008. Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant. New Phytologist. 177 (2), pp. 128-141. https://doi.org/10.1111/j.1469-8137.2007.02263.x

The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism

A - Papers appearing in refereed journals

Achard, P., Gong, F., Cheminant, S., Alioua, M., Hedden, P. and Genschik, P. 2008. The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism. The Plant Cell. 20, pp. 2117-2129. https://doi.org/10.1105/tpc.108.058941

Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola

A - Papers appearing in refereed journals

Bomke, C., Rojas, M. C., Gong, F., Hedden, P. and Tudzynski, B. 2008. Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola. Applied and Environmental Microbiology. 74, pp. 5325-5339. https://doi.org/10.1128/AEM.00694-08

Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis

A - Papers appearing in refereed journals

Ubeda-Tomas, S., Swarup, R., Coates, J., Swarup, K., Laplaze, L., Beemster, G. T. S., Hedden, P., Bhalerao, B. and Bennett, M. J. 2008. Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis. Nature Cell Biology. 10, pp. 625-628. https://doi.org/10.1038/ncb1726

Influence of electron transport proteins on the reactions catalyzed by Fusarium fujikuroi gibberellin monooxygenases

A - Papers appearing in refereed journals

Troncoso, C., Carcamo, J., Hedden, P., Tudzynski, B. and Rojas, M. C. 2008. Influence of electron transport proteins on the reactions catalyzed by Fusarium fujikuroi gibberellin monooxygenases. Phytochemistry. 69, pp. 672-683. https://doi.org/10.1016/j.phytochem.2007.08.026

The gibberellin biosynthetic genes AtGA20ox1 and AtGA20ox2 act, partially redundantly, to promote growth and development throughout the Arabidopsis lifecycle

A - Papers appearing in refereed journals

Rieu, I., Ruiz-Rivero, O., Fernandez-Garcia, N., Griffiths, J., Powers, S. J., Gong, F., Linhartova, T., Eriksson, S., Nilsson, O., Thomas, S. G., Phillips, A. L. and Hedden, P. 2008. The gibberellin biosynthetic genes AtGA20ox1 and AtGA20ox2 act, partially redundantly, to promote growth and development throughout the Arabidopsis lifecycle. The Plant Journal. 53 (3), pp. 488-504. https://doi.org/10.1111/j.1365-313X.2007.03356.x

Over-expression of a gibberellin 2-oxidase gene from Phaseolus coccineus L. enhances gibberellin inactivation and induces dwarfism in Solanum species

A - Papers appearing in refereed journals

Dijkstra, C., Adams, E., Bhattacharya, A., Page, A. F., Anthony, P., Kourmpetli, S., Power, J. B., Lowe, K. C., Thomas, S. G., Hedden, P., Phillips, A. L. and Davey, M. R. 2008. Over-expression of a gibberellin 2-oxidase gene from Phaseolus coccineus L. enhances gibberellin inactivation and induces dwarfism in Solanum species. Plant Cell Reports. 27, pp. 463-470. https://doi.org/10.1007/s00299-007-0471-z

Genetic modification of plant stature by manipulation of gibberellin metabolism: an alternative to chemical growth regulators

C2 - Non-edited contributions to conferences

Bhattacharya, A., Davey, M., Power, B., Ward, D. A., Phillips, A. L. and Hedden, P. 2007. Genetic modification of plant stature by manipulation of gibberellin metabolism: an alternative to chemical growth regulators. https://doi.org/10.1016/j.cbpa.2007.01.623

Ethylene-induced Arabidopsis hypocotyl elongation is dependent on but not mediated by gibberellins

A - Papers appearing in refereed journals

Vandenbussche, F., Vancompernolle, B., Rieu, I., Ahmad, M., Phillips, A. L., Moritz, T., Hedden, P. and Van Der Straeten, D. 2007. Ethylene-induced Arabidopsis hypocotyl elongation is dependent on but not mediated by gibberellins. Journal of Experimental Botany. 58, pp. 4269-4281. https://doi.org/10.1093/jxb/erm288

Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat

A - Papers appearing in refereed journals

Appleford, N. E., Wilkinson, M. D., Ma, Q., Evans, D. J., Stone, M. C., Pearce, S. P., Powers, S. J., Thomas, S. G., Jones, H. D., Phillips, A. L., Hedden, P. and Lenton, J. R. 2007. Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat. Journal of Experimental Botany. 58, pp. 3213-3226. https://doi.org/10.1093/jxb/erm166

Reciprocal influence of ethylene and gibberellins on response-gene expression in Arabadopsis thaliana

A - Papers appearing in refereed journals

De Grauwe, L., Vriezen, W. H., Bertrand, S., Phillips, A. L., Vidal, A. M., Hedden, P. and Van Der Straeten, D. 2007. Reciprocal influence of ethylene and gibberellins on response-gene expression in Arabadopsis thaliana. Planta. 226, pp. 485-498. https://doi.org/10.1007/s00425-007-0499-x

The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism

A - Papers appearing in refereed journals

Dai, M., Zhao, Y., Ma, Q., Hu, Y., Hedden, P., Zhang, Q. and Zhou, D-X. 2007. The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism. Plant Physiology. 144, pp. 121-133. https://doi.org/10.1104/pp.107.096586

The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes

A - Papers appearing in refereed journals

Achard, P., Baghour, M., Chapple, A., Hedden, P., Van Der Straeten, D., Genschik, P., Moritz, T. and Harberd, N. P. 2007. The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes. Proceedings of the National Academy of Sciences. 104, pp. 6484-6489. https://doi.org/10.1073/pnas.0610717104

Gibberellin metabolism and signal transduction

B - Book chapters etc edited externally

Hedden, P. and Thomas, S. G. 2006. Gibberellin metabolism and signal transduction. in: Hedden, P. and Thomas, S. G. (ed.) In: Annual Plant Reviews Volume 24: Plant Hormone Signaling (Chapter 6) Blackwell Publishing Oxford.

Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis

A - Papers appearing in refereed journals

Griffiths, J., Murase, K., Rieu, I., Zentella, R., Zhang, Z-L., Powers, S. J., Gong, F., Phillips, A. L., Hedden, P., Sun, T-P. and Thomas, S. G. 2006. Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis. The Plant Cell. 18 (12), pp. 3399-3414. https://doi.org/10.1105/tpc.106.047415

Transcriptional regulation of gibberellin metabolism genes by auxin signaling in Arabidopsis

A - Papers appearing in refereed journals

Frigerio, M., Alabadi, D., Perez-Gomez, J., Garcia-Carcel, L., Phillips, A. L., Hedden, P. and Blazquez, M. A. 2006. Transcriptional regulation of gibberellin metabolism genes by auxin signaling in Arabidopsis. Plant Physiology. 142, pp. 553-563. https://doi.org/10.1104/pp.106.084871

Overexpression of a bacterial 1-deoxy-D-xylulose 5-phosphate synthase gene in potato tubers perturbs the isoprenoid metabolic network: implications for the control of the tuber life cycle

A - Papers appearing in refereed journals

Morris, W. L., Ducreux, L. J. M., Hedden, P., Millam, S. and Taylor, M. A. 2006. Overexpression of a bacterial 1-deoxy-D-xylulose 5-phosphate synthase gene in potato tubers perturbs the isoprenoid metabolic network: implications for the control of the tuber life cycle. Journal of Experimental Botany. 57, pp. 3007-3018. https://doi.org/10.1093/jxb/erl061

Long-term submergence-induced elongation in Rumex palustris requires abscisic acid-dependent biosynthesis of gibberellin1

A - Papers appearing in refereed journals

Benschop, J. J., Bou, J., Peeters, A. J. M., Wagemaker, N., Guhl, K., Ward, D. A., Hedden, P., Moritz, T. and Voesenek, L. A. C. J. 2006. Long-term submergence-induced elongation in Rumex palustris requires abscisic acid-dependent biosynthesis of gibberellin1. Plant Physiology. 141, pp. 1644-1652. https://doi.org/10.1104/pp.106.082636

Function and transcript analysis of gibberellin-biosynthetic enzymes in wheat

A - Papers appearing in refereed journals

Appleford, N. E. J., Evans, D. J., Lenton, J. R., Gaskin, P., Croker, S. J., Devos, K. M., Phillips, A. L. and Hedden, P. 2006. Function and transcript analysis of gibberellin-biosynthetic enzymes in wheat. Planta. 223, pp. 568-582. https://doi.org/10.1007/s00425-005-0104-0

A Novel Dwarfing Mutation in a Green Revolution Gene from Brassica rapa

A - Papers appearing in refereed journals

Muangprom, A., Thomas, S. G., Sun, T-P. and Osborn, T. C. 2005. A Novel Dwarfing Mutation in a Green Revolution Gene from Brassica rapa. Plant Physiology. 137 (3), pp. 931-938. https://doi.org/10.1104/pp.104.057646

Gibberellin metabolism and signaling

A - Papers appearing in refereed journals

Thomas, S. G., Rieu, I. and Steber, C. M. 2005. Gibberellin metabolism and signaling. Vitamins and Hormones. 72, pp. 289-338. https://doi.org/10.1016/S0083-6729(05)72009-4

Restoration of gibberellin production in Fusarium proliferatum by functional complementation of enzymatic blocks

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Hopkins, P. and Tudzynski, B. 2005. Restoration of gibberellin production in Fusarium proliferatum by functional complementation of enzymatic blocks. Applied and Environmental Microbiology. 71, pp. 6014-6025.

Purification and kinetic studies of recombinant gibberellin dioxygenases

A - Papers appearing in refereed journals

Lester, D. R., Phillips, A. L., Hedden, P. and Andersson, I. 2005. Purification and kinetic studies of recombinant gibberellin dioxygenases. BMC Plant Biology. 5:19. https://doi.org/10.1186/1471-2229-5-19

Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4 , of the gibberellic acid gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D)

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Gaskin, P., Hopkins, P. and Tudzynski, B. 2005. Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4 , of the gibberellic acid gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D). Applied and Environmental Microbiology. 71, pp. 1462-1472.

Modification of gibberellin biosynthesis in the grafted apple scion allows control of tree height independent of the rootstock

A - Papers appearing in refereed journals

Bulley, S. M., Wilson, F. M., Hedden, P., Phillips, A. L., Croker, S. J. and James, D. J. 2005. Modification of gibberellin biosynthesis in the grafted apple scion allows control of tree height independent of the rootstock. Plant Biotechnology Journal. 3 (2), pp. 215-223. https://doi.org/10.1111/j.1467-7652.2005.00119.x

The auxin transport inhibitor response 3 (tir3) allele of BIG and auxin transport inhibitors affect the gibberellin status of Arabidopsis

A - Papers appearing in refereed journals

Desgagne-Penix, I., Eakanunkul, S., Coles, J. P., Phillips, A. L., Hedden, P. and Sponsel, V. 2005. The auxin transport inhibitor response 3 (tir3) allele of BIG and auxin transport inhibitors affect the gibberellin status of Arabidopsis. The Plant Journal. 41 (2), pp. 231-242. https://doi.org/10.1111/j.1365-313X.2004.02287.x

Gibberellin biosynthesis and inactivation

B - Book chapters etc edited externally

Sponsel, V. M. and Hedden, P. 2004. Gibberellin biosynthesis and inactivation. in: Davies, P. J. (ed.) Plant hormones - biosynthesis, signal transduction, action! 3rd ed. Kluwer Academic Publishers, Dordrecht, Netherlands. pp. 63-94

Reduced stature plants (Patent application)

H2 - Patents applied for

Phillips, A. L., Hedden, P., Bulley, S. M. W. and James, D. J. 2004. Reduced stature plants (Patent application).

The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation

A - Papers appearing in refereed journals

Dill, A., Thomas, S. G., Hu, J., Steber, C. M. and Sun, T-P. 2004. The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation. The Plant Cell. 16, pp. 1392-1405.

DELLA proteins and gibberellin-regulated seed germination and floral development in Arabidopsis

A - Papers appearing in refereed journals

Tyler, L., Thomas, S. G., Hu, J., Dill, A., Alonso, J. M., Ecker, J. R. and Sun, T-P. 2004. DELLA proteins and gibberellin-regulated seed germination and floral development in Arabidopsis. Plant Physiology. 135, pp. 1008-1019.

Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi

A - Papers appearing in refereed journals

Rojas, M. C., Urrutia, O., Cruz, C., Gaskin, P., Tudzynski, B. and Hedden, P. 2004. Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi. Phytochemistry. 65, pp. 821-830.

Update on gibberellin signaling. A tale of the tall and the short

A - Papers appearing in refereed journals

Thomas, S. G. and Sun, T-P. 2004. Update on gibberellin signaling. A tale of the tall and the short. Plant Physiology. 135, pp. 668-676.

The NADPH-cytochrome P450 reductase gene from Gibberella fujikuroi is essential for gibberellin biosynthesis

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Gaskin, P., Hopkins, P. and Tudzynski, B. 2004. The NADPH-cytochrome P450 reductase gene from Gibberella fujikuroi is essential for gibberellin biosynthesis. Journal of Biological Chemistry. 279, pp. 25075-25084.

Gibberellins

B - Book chapters etc edited externally

Hedden, P. 2003. Gibberellins. in: Thomas, B., Murray, B. G. and Murphy, D. J. (ed.) Encyclopedia of applied plant sciences Academic Press Inc New York. pp. 1011-1019

Production and characterization of transgenic wheat with altered gibberellin catabolism

C2 - Non-edited contributions to conferences

Evans, D. J., Stone, M., Appleford, N. E. J., Wilkinson, M. D., Jones, H. D., Ma, Q., Croker, S. J., Phillips, A. L., Hedden, P. and Lenton, J. R. 2003. Production and characterization of transgenic wheat with altered gibberellin catabolism.

Controlling stature in apple trees by genetic modification of gibberellin biosynthesis

C2 - Non-edited contributions to conferences

Bulley, S. M. W., James, D. J., Phillips, A. L. and Hedden, P. 2003. Controlling stature in apple trees by genetic modification of gibberellin biosynthesis.

Molecular characterisation of the GA 20-oxidase-1 promoter from Arabidopsis : identification of cis-elements that mediate control of gene expression by gibberellins

C2 - Non-edited contributions to conferences

Ruiz, O., Coles, J., Hedden, P. and Phillips, A. L. 2003. Molecular characterisation of the GA 20-oxidase-1 promoter from Arabidopsis : identification of cis-elements that mediate control of gene expression by gibberellins.

Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively

A - Papers appearing in refereed journals

Tudzynski, B., Mihlan, M., Rojas, M. C., Linnemannstons, P., Gaskin, P. and Hedden, P. 2003. Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively. Journal of Biological Chemistry. 278, pp. 28635-28643.

Constructing dwarf rice

A - Papers appearing in refereed journals

Hedden, P. 2003. Constructing dwarf rice. Nature Biotechnology. 21 (8), pp. 873-874. https://doi.org/10.1038/nbt0803-873

The genes of the Green Revolution

A - Papers appearing in refereed journals

Hedden, P. 2003. The genes of the Green Revolution. Trends in Genetics. 19, pp. 5-9.

Interactions between plant hormone signalling and gibberellin biosynthesis

C2 - Non-edited contributions to conferences

Clark, N. R., Coles, J. P., Ruiz, O., Hedden, P. and Phillips, A. L. 2003. Interactions between plant hormone signalling and gibberellin biosynthesis.

New approach to achieve tissue-specific transgene expression in plants

C2 - Non-edited contributions to conferences

Roden, L. C., Phillips, A. L., Hedden, P. and Mutasa-Göttgens, E. S. 2002. New approach to achieve tissue-specific transgene expression in plants. Abstracts 10th Plant, Animal and Microbe Genomes Conference, San Diego, 12-16 January 2002 .

The gibberellin pathway mediates KNOTTED1-type homeobox function in plants with different body plans

A - Papers appearing in refereed journals

Hay, A., Kaur, H., Phillips, A. L., Hedden, P., Hake, S. and Tsiantis, M. 2002. The gibberellin pathway mediates KNOTTED1-type homeobox function in plants with different body plans. Current Biology. 12, pp. 1557-1565. https://doi.org/10.1016/S0960-9822(02)01125-9

Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone

A - Papers appearing in refereed journals

Wong, J. H., Kim, Y-B., Ren, P-H., Cai, N., Cho, M-J., Hedden, P., Lemaux, P. G. and Buchanan, B. B. 2002. Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone. Proceedings of the National Academy of Sciences. 99 (25), pp. 16325-16330. https://doi.org/10.1073/pnas.212641999

The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase

A - Papers appearing in refereed journals

Tudzynski, B., Rojas, M. C., Gaskin, P. and Hedden, P. 2002. The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase. Journal of Biological Chemistry. 277, pp. 21246-21253.

Probing the mechanism of loss of carbon-20 in gibberellin biosynthesis. Synthesis of gibberellin 3alpha,20-hemiacetal and 19,20-lactol analogues and their metabolism by a recombinant GA 20-oxidase

A - Papers appearing in refereed journals

Ward, J. L., Gaskin, P., Brown, R. G. S., Jackson, G. S., Hedden, P., Phillips, A. L., Willis, C. L. and Beale, M. H. 2002. Probing the mechanism of loss of carbon-20 in gibberellin biosynthesis. Synthesis of gibberellin 3alpha,20-hemiacetal and 19,20-lactol analogues and their metabolism by a recombinant GA 20-oxidase. Journal of the Chemical Society-Perkin Transactions 1. 2002, pp. 232-241.

Gibberellin Biosynthesis in Plants and Fungi: A Case of Convergent Evolution?

A - Papers appearing in refereed journals

Hedden, P., Phillips, A. L., Rojas, M. C., Carrera, E. and Tudzynski, B. 2001. Gibberellin Biosynthesis in Plants and Fungi: A Case of Convergent Evolution? Journal of Plant Growth Regulation. 20 (4), pp. 319-331. https://doi.org/10.1007/s003440010037

Monooxygenases involved in GA12 and GA14 synthesis in Gibberella fujikuroi

A - Papers appearing in refereed journals

Urrutia, O., Hedden, P. and Rojas, M. C. 2001. Monooxygenases involved in GA12 and GA14 synthesis in Gibberella fujikuroi. Phytochemistry. 56, pp. 505-511.

The P450-4 gene of Gibberella fujikuroi encodes ent -kaurene oxidase in the gibberellin biosynthesis pathway

A - Papers appearing in refereed journals

Tudzynski, B., Hedden, P., Carrera, E. and Gaskin, P. 2001. The P450-4 gene of Gibberella fujikuroi encodes ent -kaurene oxidase in the gibberellin biosynthesis pathway. Applied and Environmental Microbiology. 67, pp. 3514-3522.

The P450-1 gene of Gibberella fujikuroi encodes a multifunctional enzyme in gibberellin biosynthesis

A - Papers appearing in refereed journals

Rojas, M. C., Hedden, P., Gaskin, P. and Tudzynski, B. 2001. The P450-1 gene of Gibberella fujikuroi encodes a multifunctional enzyme in gibberellin biosynthesis. Proceedings of the National Academy of Sciences. 98 (10), pp. 5838-5843. https://doi.org/10.1073/pnas.091096298

Production of dwarf lettuce by overexpressing a pumpkin gibberellin 20-oxidase gene

A - Papers appearing in refereed journals

Niki, T., Nishijima, T., Nakayama, M., Hisamatsu, T., Oyama-Okubo, N., Yamazaki, H., Hedden, P., Lange, T., Mander, L. T. and Koshioka, M. 2001. Production of dwarf lettuce by overexpressing a pumpkin gibberellin 20-oxidase gene. Plant Physiology. 126, pp. 965-972.

Workshop on Biochemistry and Molecular Biology of Gibberellins, Madrid, 27-29 March 2000

B - Book chapters etc edited externally

Hedden, P. 2000. Workshop on Biochemistry and Molecular Biology of Gibberellins, Madrid, 27-29 March 2000. in: Garcia-Martinez, J. L. (ed.) Instituto Juan March de Estudios e Investagaciones, Madrid. pp. 81pp

Hormone Engineering in Plants [La manipulation des hormones chez les plantes]

G - Articles in popular magazines and other technical publications

Hedden, P. and Phillips, A. L. 2000. Hormone Engineering in Plants [La manipulation des hormones chez les plantes]. Biofutur. 204, pp. 46-48. https://doi.org/10.1016/S0294-3506(00)80170-2

Effects of prohexadione-Ca on gibberellin levels in young apple shoots

C2 - Non-edited contributions to conferences

Croker, S. J., Hedden, P. and Rademacher, W. 2000. Effects of prohexadione-Ca on gibberellin levels in young apple shoots.

Gibberellin metabolism: new insights revealed by the genes

A - Papers appearing in refereed journals

Hedden, P. and Phillips, A. L. 2000. Gibberellin metabolism: new insights revealed by the genes. Trends in Plant Science. 5 (12), pp. 523-530. https://doi.org/10.1016/s1360-1385(00)01790-8

Gibberellins and seed development in maize. I. Evidence that gibberellin/ abscisic acid balance governs germination versus maturation pathways

A - Papers appearing in refereed journals

White, C. N., Proebsting, W. M., Hedden, P. and Rivin, . J. 2000. Gibberellins and seed development in maize. I. Evidence that gibberellin/ abscisic acid balance governs germination versus maturation pathways. Plant Physiology. 122, pp. 1081-1088.

Manipulation of hormone biosynthetic genes in transgenic plants

A - Papers appearing in refereed journals

Hedden, P. and Phillips, A. L. 2000. Manipulation of hormone biosynthetic genes in transgenic plants. Current Opinion in Biotechnology. 11, pp. 130-137.

Transformation and characterization of transgenic plants of Solanum dulcamara L. - incidence of transgene silencing

A - Papers appearing in refereed journals

Curtis, I. S., Power, J. B., Hedden, P., Phillips, A. L., Lowe, K. C., Ward, D. A. and Davey, M. R. 2000. Transformation and characterization of transgenic plants of Solanum dulcamara L. - incidence of transgene silencing. Annals of Botany. 86, pp. 63-71.

Induction of dwarfism in transgenic Solanum dulcamara by over-expression of a gibberellin 20-oxidase cDNA from pumpkin

A - Papers appearing in refereed journals

Curtis, I. S., Ward, D. A., Thomas, S. G., Phillips, A. L., Davey, M. R., Power, J. B., Lowe, K. C., Croker, S. J., Lewis, M. J., Magness, S. L. and Hedden, P. 2000. Induction of dwarfism in transgenic Solanum dulcamara by over-expression of a gibberellin 20-oxidase cDNA from pumpkin. The Plant Journal. 23, pp. 329-338.

Genetic Analysis of Gibberellin Biosynthesis

A - Papers appearing in refereed journals

Hedden, P. and Proebsting, W. M. 1999. Genetic Analysis of Gibberellin Biosynthesis. Plant Physiology. 119 (2), pp. 365-370. https://doi.org/10.1104/pp.119.2.365

Modification of gibberellin production and plant development in Arabidopsis by sense and antisense expression of gibberellin 20‐oxidase genes

A - Papers appearing in refereed journals

Coles, J. P., Phillips, A. L., Croker, S. J., García‐Lepe, R., Lewis , M. J. and Hedden, P. 1999. Modification of gibberellin production and plant development in Arabidopsis by sense and antisense expression of gibberellin 20‐oxidase genes. The Plant Journal. 17 (5), pp. 547-556. https://doi.org/10.1046/j.1365-313X.1999.00410.x

Molecular cloning and functional expression of gibberellin 2-oxidases, multifunctional enzymes involved in gibberellin deactivation

A - Papers appearing in refereed journals

Thomas, S. G., Phillips, A. L. and Hedden, P. 1999. Molecular cloning and functional expression of gibberellin 2-oxidases, multifunctional enzymes involved in gibberellin deactivation. Proceedings of the National Academy of Sciences. 96 (8), pp. 4698-4703. https://doi.org/10.1073/pnas.96.8.4698

Genetic engineering for bolting resistance

C1 - Edited contributions to conferences/learned societies

Van Roggen, P. M., Thomas, S. G., Hedden, P., Phillips, A. L., Debenham, G. B., Scott, R. W. and Mathews, A. M. 1997. Genetic engineering for bolting resistance. Proceedings 60th Congress of the Institut International de Recherches Betteravieres, Cambridge, July 1997 . pp. 571-574

Isolation and Expression of Three Gibberellin 20-Oxidase cDNA Clones from Arabidopsis

A - Papers appearing in refereed journals

Phillips, A. L., Ward, D. A., Uknes, S., Appleford, N. E. J., Lange, T., Huttly, A. K., Gaskin, P., Graebe, J. E. and Hedden, P. 1995. Isolation and Expression of Three Gibberellin 20-Oxidase cDNA Clones from Arabidopsis. Plant Physiology. 108 (3), pp. 1049-1057. https://doi.org/10.1104/pp.108.3.1049

Quantitative analysis of gibberellins by isotope dilution mass spectrometry: a comparison of the use of calibration curves, an isotope dilution fit program and arithmetical correction of isotope ratios

A - Papers appearing in refereed journals

Croker, S. J., Gaskin, P., Hedden, P., Macmillan, J. and Macneil, K. A. G. 1994. Quantitative analysis of gibberellins by isotope dilution mass spectrometry: a comparison of the use of calibration curves, an isotope dilution fit program and arithmetical correction of isotope ratios. Phytochemical Analysis. 5 (2), pp. 74-80. https://doi.org/10.1002/pca.2800050206

Effects of the triazole plant-growth retardant BAS 111¨ W on gibberellin levels in oilseed rape, Brassica napus

A - Papers appearing in refereed journals

Hedden, P., Croker, S. J., Rademacher, W. and Jung, J. 1989. Effects of the triazole plant-growth retardant BAS 111¨ W on gibberellin levels in oilseed rape, Brassica napus. Physiologia Plantarum. 75 (4), pp. 445-451. https://doi.org/10.1111/j.1399-3054.1989.tb05607.x

Synthesis and biological activity of an azido derivative of Paclobutrazol, an inhibitor of gibberelin biosynthesis.

A - Papers appearing in refereed journals

Hallahan, D. L., Heasman, A. P., Grossel, M. C., Quigley, R., Hedden, P. and Bowyer, J. R. 1989. Synthesis and biological activity of an azido derivative of Paclobutrazol, an inhibitor of gibberelin biosynthesis. Plant Physiology. 88, pp. 1425-1429.

Comparative activity of the enantiomers of triadimenol and paclobutrazol as inhibitors of fungal growth and plant sterol and gibberellin biosynthesis

A - Papers appearing in refereed journals

Burden, R. S., Carter, G. A., Clark, T., Cooke, D. T., Croker, S. J., Deas, A. H. B., Hedden, P., James, C. S. and Lenton, J. R. 1987. Comparative activity of the enantiomers of triadimenol and paclobutrazol as inhibitors of fungal growth and plant sterol and gibberellin biosynthesis. Pesticide Science. 21 (4), pp. 253-267. https://doi.org/10.1002/ps.2780210403