Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin

A - Papers appearing in refereed journals

Conti, L., Nelis, S., Zhang, C., Woodcock, A., Swarup, R., Galbiati, M., Tonelli, C., Napier, R., Hedden, P., Bennett, M. and Sadanandom, A. 2014. Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin. Developmental Cell. 28, pp. 102-110. https://doi.org/10.1016/j.devcel.2013.12.004

AuthorsConti, L., Nelis, S., Zhang, C., Woodcock, A., Swarup, R., Galbiati, M., Tonelli, C., Napier, R., Hedden, P., Bennett, M. and Sadanandom, A.
Abstract

Plants survive adverse conditions by modulating their growth in response to a changing environment. Gibberellins (GAs) play a key role in these adaptive responses by stimulating the degradation of growth-repressing DELLA proteins. GA binding to its receptor GID1 enables association of GID1 with DELLAs. This leads to the ubiquitin-mediated proteasomal degradation of DELLAs and consequently growth promotion. We report that DELLA-dependent growth control can be regulated independently of GA. We demonstrate that when a proportion of DELLAs is conjugated to the Small Ubiquitin-like Modifier (SUMO) protein, the extent of conjugation increases during stress. We identify a SUMO-interacting motif in GID1 and demonstrate that SUMO-conjugated DELLA binds to this motif in a GA-independent manner. The consequent sequestration of GID1 by SUMO-conjugated DELLAs leads to an accumulation of non-SUMOylated DELLAs, resulting in beneficial growth restraint during stress. We conclude that plants have developed a GA-independent mechanism to control growth. 

Year of Publication2014
JournalDevelopmental Cell
Journal citation28, pp. 102-110
Digital Object Identifier (DOI)https://doi.org/10.1016/j.devcel.2013.12.004
Open accessPublished as non-open access
Funder project or codeWheat
[20:20 Wheat] Maximising yield potential of wheat
Output statusPublished
Publication dates
Online13 Jan 2014
Publication process dates
Accepted06 Dec 2013
PublisherElsevier
Cell Press
ISSN1534-5807

Permalink - https://repository.rothamsted.ac.uk/item/8qy20/small-ubiquitin-like-modifier-protein-sumo-enables-plants-to-control-growth-independently-of-the-phytohormone-gibberellin

Restricted files

Publisher's version

Under embargo indefinitely

32 total views
1 total downloads
0 views this month
0 downloads this month