Jake MacMillan: A pioneering chemist in plant biology

Hedden, P. and Beale, M. H. 2014. Jake MacMillan: A pioneering chemist in plant biology. Proceedings of the National Academy of Sciences. 111 (41), pp. 14641-14642. https://doi.org/10.1073/pnas.1414365111

Authors	Hedden, P. and Beale, M. H.
Year of Publication	2014
Journal	Proceedings of the National Academy of Sciences
Journal citation	111 (41), pp. 14641-14642
Digital Object Identifier (DOI)	https://doi.org/10.1073/pnas.1414365111
Open access	Published as bronze (free) open access
Funder	Biotechnology and Biological Sciences Research Council
Funder project or code	Wheat
	[20:20 Wheat] Maximising yield potential of wheat
Publisher's version	14641.full.pdf
Publisher	National Academy of Sciences
	National Academy of Sciences of the United States of America
ISSN	0027-8424

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13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis

A - Papers appearing in refereed journals

Beste, D. J. V., Noh, K., Niedenfuhr, S., Mendum, T. A., Hawkins, N. D., Ward, J. L., Beale, M. H., Wiechert, W. and Mcfadden, J. 2013. 13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis. Chemistry and Biology. 20 (8), pp. 1012-1021. https://doi.org/10.1016/j.chembiol.2013.06.012

Metabolomic and elemental profiling of melon fruit quality as affected by genotype and environment

A - Papers appearing in refereed journals

Bernillon, S., Biais, B., Deborde, C., Maucourt, M., Cabasson, C., Gibon, Y., Hansen, T. H., Husted, S., De Vos, R. C. H., Mumm, R., Jonker, H., Ward, J. L., Miller, S. J., Baker, J. M., Burger, J., Tadmor, Y., Beale, M. H., Schjoerring, J. K., Schaffer, A. A., Rolin, D., Hall, R. D. and Moing, A. 2013. Metabolomic and elemental profiling of melon fruit quality as affected by genotype and environment. Metabolomics. 9, pp. 57-77. https://doi.org/10.1007/s11306-012-0429-1

Transcriptional changes of the root-knot nematode Meloidogyne incognita in response to Arabidopsis thaliana root signals

A - Papers appearing in refereed journals

Teillet, A., Dybal, K., Kerry, B. R., Miller, A. J., Curtis, R. H. C. and Hedden, P. 2013. Transcriptional changes of the root-knot nematode Meloidogyne incognita in response to Arabidopsis thaliana root signals. PLOS ONE. 8, p. e61259. https://doi.org/10.1371/journal.pone.0061259

Exploring the metabolome of cereal infecting fusaria

C2 - Non-edited contributions to conferences

Hammond-Kosack, K. E., Lowe, R. G. T., Canning, G., Urban, M., Beale, M. H. and Ward, J. L. 2013. Exploring the metabolome of cereal infecting fusaria. Abstracts 27th Fungal Genetics Conference, Asilomar, 12-17 March 2013 . pp. 21

Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density

A - Papers appearing in refereed journals

Hodge, S., Ward, J. L., Beale, M. H., Bennett, M., Mansfield, J. W. and Powell, G. 2013. Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density. Planta. 237, pp. 1057-1064. https://doi.org/10.1007/s00425-012-1826-4

Development of new quantitative physiological and molecular breeding parameters based on the sugar-beet vernalization intensity model

A - Papers appearing in refereed journals

Chiurugwi, T., Holmes, H. F., Qi, A., Chia, T. Y. P., Hedden, P. and Mutasa-Göttgens, E. S. 2013. Development of new quantitative physiological and molecular breeding parameters based on the sugar-beet vernalization intensity model. The Journal of Agricultural Science. 151, pp. 492-505. https://doi.org/10.1017/S0021859612000573

Effects of exogenous abscisic acid and gibberellic acid on pre-maturity alpha-amylase formation in wheat grains

A - Papers appearing in refereed journals

Kondhare, K., Kettlewell, P., Farrell, A., Hedden, P. and Monaghan, J. 2012. Effects of exogenous abscisic acid and gibberellic acid on pre-maturity alpha-amylase formation in wheat grains. Euphytica. 188 (1), pp. 51-60. https://doi.org/10.1007/s10681-012-0706-0

A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase

A - Papers appearing in refereed journals

Criswell, J., Potter, K., Shephard, F., Beale, M. H. and Peters, R. J. 2012. A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase. Organic Letters. 14, pp. 5828-5831. https://doi.org/10.1021/ol3026022

Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum

A - Papers appearing in refereed journals

Studt, L., Troncoso, C., Gong, F., Hedden, P., Toomajian, C., Leslie, J. F., Humpf, H-U., Rojas, M. C. and Tudzynski, B. 2012. Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum. Fungal Genetics and Biology. 49, pp. 567-577. https://doi.org/10.1016/j.fgb.2012.05.005

A short history of gibberellin biosynthesis: a very personal perspective

A - Papers appearing in refereed journals

Hedden, P. 2012. A short history of gibberellin biosynthesis: a very personal perspective. Regulation of Plant Growth and Development. 47 (1), pp. 52-57.

Gibberellin biosynthesis inhibitors help control plant height for improving lodging resistance in E. Tef (Eragrostis tef)

A - Papers appearing in refereed journals

Gebre, E., Schluter, U., Hedden, P. and Kunert, K. 2012. Gibberellin biosynthesis inhibitors help control plant height for improving lodging resistance in E. Tef (Eragrostis tef). Journal of Crop Improvement. 26, pp. 375-388. https://doi.org/10.1080/15427528.2011.646056

Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling

A - Papers appearing in refereed journals

Middleton, A. M., Ubeda-Tomas, S., Griffiths, J., Holman, T., Hedden, P., Thomas, S. G., Phillips, A. L., Holdsworthy, M. J., Bennett, M. J., King, J. R. and Owen, M. R. 2012. Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling. Proceedings of the National Academy of Sciences. 109, pp. 7571-7576. https://doi.org/10.1073/pnas.1113666109

Genetic and physiological analysis of Rht8 in bread wheat: an alternative source of semi-dwarfism with a reduced sensitivity to brassinosteroids

A - Papers appearing in refereed journals

Gasperini, D., Greenland, A., Hedden, P., Dreos, R., Harwood, W. and Griffiths, S. 2012. Genetic and physiological analysis of Rht8 in bread wheat: an alternative source of semi-dwarfism with a reduced sensitivity to brassinosteroids. Journal of Experimental Botany. 63, pp. 4419-4436. https://doi.org/10.1093/jxb/ers138

The characterization of transgenic tomato overexpressing gibberellin 20-oxidase reveals induction of the parthenocarpic fruit growth, higher yield and alteration of the gibberellin biosynthetic pathway

A - Papers appearing in refereed journals

Garcia-Hurtado, N., Carrera, E., Ruiz-Rivero, O., Lopez-Gresa, M. P., Hedden, P., Gong, F. and Garcia-Martinez, J. L. 2012. The characterization of transgenic tomato overexpressing gibberellin 20-oxidase reveals induction of the parthenocarpic fruit growth, higher yield and alteration of the gibberellin biosynthetic pathway. Journal of Experimental Botany. 63, pp. 5803-5813. https://doi.org/10.1093/jxb/ers229

Leaf-induced gibberellin signaling is essential for internode elongation, cambial activity and fiber differentiation in tobacco stems

A - Papers appearing in refereed journals

Dayan, J., Voronin, N., Gong, F., Sun, T-P., Hedden, P., Fromm, H. and Aloni, R. 2012. Leaf-induced gibberellin signaling is essential for internode elongation, cambial activity and fiber differentiation in tobacco stems. The Plant Cell. 24, pp. 66-79. https://doi.org/10.1105/tpc.111.093096

Characterization of the fungal gibberellin desaturase as a 2-oxoglutarate-dependent dioxygenase and its utilization for enhancing plant growth

A - Papers appearing in refereed journals

Bhattacharya, A., Kourmpetli, S., Ward, D. A., Thomas, S. G., Gong, F., Powers, S. J., Carrera, E., Taylor, B., Nunez De Caceres Gonzalez, F., Tudzynski, B., Phillips, A. L., Davey, M. R. and Hedden, P. 2012. Characterization of the fungal gibberellin desaturase as a 2-oxoglutarate-dependent dioxygenase and its utilization for enhancing plant growth. Plant Physiology. 160, pp. 837-845. https://doi.org/10.1104/pp.112.201756

Unexpected hemiterpenoids in Arabidopsis, revealed by metabolomic fingerprinting, give new insights into C/N metabolic balancing

C2 - Non-edited contributions to conferences

Ward, J. L., Baker, J. M., Llewellyn, A. M., Hawkins, N. D. and Beale, M. H. 2012. Unexpected hemiterpenoids in Arabidopsis, revealed by metabolomic fingerprinting, give new insights into C/N metabolic balancing. Taylor & Francis.

A new RNASeq-based reference transcriptome for sugar beet and its application in transcriptome-scale analysis of vernalization and gibberellin responses

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S., Joshi, A., Holmes, H. F., Hedden, P. and Gottgens, B. 2012. A new RNASeq-based reference transcriptome for sugar beet and its application in transcriptome-scale analysis of vernalization and gibberellin responses. BMC Genomics. 13, p. 99. https://doi.org/10.1186/1471-2164-13-99

Effects of genotype and environment on the contents of betaine, choline and trigonelline in cereal grains

A - Papers appearing in refereed journals

Corol, D. I., Ravel, C., Raksegi, M., Bedo, Z., Charmet, G., Beale, M. H., Shewry, P. R. and Ward, J. L. 2012. Effects of genotype and environment on the contents of betaine, choline and trigonelline in cereal grains. Journal of Agricultural and Food Chemistry - JAFC. 60, pp. 5471-5481. https://doi.org/10.1021/jf3008794

Realising the potential of plant metabolomics

C2 - Non-edited contributions to conferences

Beale, M. H. and Ward, J. L. 2012. Realising the potential of plant metabolomics.

Analysis of the developmental roles of the Arabidopsis gibberellin 20-oxidases demonstrates that GA20ox1, -2 and -3 are the dominant paralogs

A - Papers appearing in refereed journals

Plackett, A. R. G., Powers, S. J., Fernandez-Garcia, N., Urbanova, T., Takebayashi, Y., Seo, M., Jikumaru, Y., Benlloch, R., Nilsson, O., Ruiz-Rivero, O., Phillips, A. L., Wilson, Z. A., Thomas, S. G. and Hedden, P. 2012. Analysis of the developmental roles of the Arabidopsis gibberellin 20-oxidases demonstrates that GA20ox1, -2 and -3 are the dominant paralogs. The Plant Cell. 24, pp. 941-960. https://doi.org/10.1105/tpc.111.095109

Gibberellin biosynthesis and its regulation

A - Papers appearing in refereed journals

Hedden, P. and Thomas, S. G. 2012. Gibberellin biosynthesis and its regulation. Biochemical Journal. 444, pp. 11-25. https://doi.org/10.1042/BJ20120245

Engineering gibberellin metabolism in Solanum nigrum L. by ectopic expression of gibberellin oxidase genes

A - Papers appearing in refereed journals

Bhattacharya, A., Ward, D. A., Hedden, P., Phillips, A. L., Power, J. B. and Davey, M. R. 2012. Engineering gibberellin metabolism in Solanum nigrum L. by ectopic expression of gibberellin oxidase genes. Plant Cell Reports. 31, pp. 945-953. https://doi.org/10.1007/s00299-011-1214-8

2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation

A - Papers appearing in refereed journals

Andralojc, P. J., Madgwick, P. J., Tao, Y., Keys, A. J., Ward, J. L., Beale, M. H., Loveland, J. E., Jackson, P. J., Willis, A. C., Gutteridge, S. and Parry, M. A. J. 2012. 2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation. Biochemical Journal. 442 (3), pp. 733-742. https://doi.org/10.1042/BJ20111443

Tissue preparation using Arabidopsis

B - Book chapters etc edited externally

Llewellyn, A. M., Lewis, J., Miller, S. J., Corol, D. I., Beale, M. H. and Ward, J. L. 2012. Tissue preparation using Arabidopsis. in: Hall, R. D. and Hardy, N. W. (ed.) Plant metabolomics: methods and protocols (Methods in Molecular Biology, vol. 860 Springer, New York. pp. 65-81

Combined NMR and flow injection ESI-MS for Brassicaceae metabolomics

B - Book chapters etc edited externally

Baker, J. M., Ward, J. L. and Beale, M. H. 2012. Combined NMR and flow injection ESI-MS for Brassicaceae metabolomics. in: Hall, R. D. and Hardy, N. W. (ed.) Plant metabolomics: methods and protocols (Methods in Molecular Biology, vol. 860) Springer, New York. pp. 177-191

The role of gibberellin in determining wheat grain size and quality

C2 - Non-edited contributions to conferences

Vaughan, S. P., Wanchoo-Kohli, A., Patil, A., Huttly, A. K., Phillips, A. L. and Hedden, P. 2011. The role of gibberellin in determining wheat grain size and quality. ABRATES.

The role of gibberellin in determining wheat grain size and quality

C1 - Edited contributions to conferences/learned societies

Vaughan, S. P., Wanchoo-Kohli, A., Patil, A., Huttly, A. K., Phillips, A. L. and Hedden, P. 2011. The role of gibberellin in determining wheat grain size and quality. GM Crops: from Basic Research to Application. Aspects of Applied Biology 110 . Association of Applied Biologists (AAB) Wellesbourne Warwick . pp. 14

The effects of a plant defence priming compound, beta-aminobutyric acid, on multitrophic interactions with an insect herbivore and a hymenopterous parasitoid

A - Papers appearing in refereed journals

Hodge, S., Ward, J. L., Galster, A. M., Beale, M. H. and Powell, G. 2011. The effects of a plant defence priming compound, beta-aminobutyric acid, on multitrophic interactions with an insect herbivore and a hymenopterous parasitoid. BioControl. 56, pp. 699-711. https://doi.org/10.1007/s10526-011-9344-z

Gibberellins - terpenoid plant hormones: biological importance and chemical analysis

A - Papers appearing in refereed journals

Urbanova, T., Tarkowska, D., Strnad, M. and Hedden, P. 2011. Gibberellins - terpenoid plant hormones: biological importance and chemical analysis. Collection of Czechoslovak Chemical Communications. 76, pp. 1669-1686. https://doi.org/10.1135/cccc2011098

Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat

A - Papers appearing in refereed journals

Pearce, S., Saville, R., Vaughan, S. P., Chandler, P. M., Wilhelm, E. P., Sparks, C. A., Al-Kaff, N., Korolev, A., Boulton, M. I., Phillips, A. L., Hedden, P., Nicholson, P. and Thomas, S. G. 2011. Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat. Plant Physiology. 157, pp. 1820-1831. https://doi.org/10.1104/pp.111.183657

The transcription factor ABI4 is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis

A - Papers appearing in refereed journals

Kerchev, P. I., Pellny, T. K., Vivancos, P. D., Kiddle, G., Hedden, P., Driscoll, S. P., Vanacker, H., Verrier, P. J., Hancock, R. D. and Foyer, C. H. 2011. The transcription factor ABI4 is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis. The Plant Cell. 23, pp. 3319-3334. https://doi.org/10.1105/tpc.111.090100

Metabolomic analysis of Arabidopsis reveals hemiterpenoid glycosides as products of a nitrate ion-regulated, carbon flux overflow

A - Papers appearing in refereed journals

Ward, J. L., Baker, J. M., Llewellyn, A. M., Hawkins, N. D. and Beale, M. H. 2011. Metabolomic analysis of Arabidopsis reveals hemiterpenoid glycosides as products of a nitrate ion-regulated, carbon flux overflow. Proceedings of the National Academy of Sciences. 108, pp. 10762-10767. https://doi.org/10.1073/pnas.1018875108

Heterosis in rice seedlings: its relationship to gibberellin content and expression of gibberellin metabolism and signaling genes

A - Papers appearing in refereed journals

Ma, Q., Hedden, P. and Zhang, Q. 2011. Heterosis in rice seedlings: its relationship to gibberellin content and expression of gibberellin metabolism and signaling genes. Plant Physiology. 156, pp. 1905-1920. https://doi.org/10.1104/pp.111.178046

Gibberellin control of stamen development: a fertile field

A - Papers appearing in refereed journals

Plackett, A. R. G., Thomas, S. G., Wilson, Z. A. and Hedden, P. 2011. Gibberellin control of stamen development: a fertile field. Trends in Plant Science. 16, pp. 568-578. https://doi.org/10.1016/j.tplants.2011.06.007

13C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation

A - Papers appearing in refereed journals

Beste, D. J. V., Bonde, B., Hawkins, N. D., Ward, J. L., Beale, M. H., Noack, S., Noh, K., Kruger, N. J., Ratcliffe, R. G. and Mcfadden, J. 2011. 13C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. PLOS Pathogens. 7, p. e1002091 (18pp). https://doi.org/10.1371/journal.ppat.1002091

Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin

A - Papers appearing in refereed journals

Hartmann, A., Senning, M., Hedden, P., Sonnewald, U. and Sonnewald, S. 2011. Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin. Plant Physiology. 155, pp. 776-796. https://doi.org/10.1104/pp.110.168252

Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress

A - Papers appearing in refereed journals

Fernandez-Garcia, N., Hernandez, M., Casado-Vela, J., Bru, R., Elortza, F., Hedden, P. and Olmos, E. 2011. Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress. Plant, Cell and Environment. 34 (5), pp. 821-836. https://doi.org/10.1111/j.1365-3040.2011.02285.x

Metabolomics of Arabidopsis thaliana

B - Book chapters etc edited externally

Beale, M. H. and Sussman, M. R. 2011. Metabolomics of Arabidopsis thaliana. in: Hall, R. D. (ed.) Biology of plant metabolomics (Annual Plant Reviews Vol. 43) Wiley-Blackwell Chichester, Sussex. pp. 157-180

Gibberellin signalling - new opportunities for crop management

G - Articles in popular magazines and other technical publications

Hedden, P., Rademacher, W. and Phillips, A. L. 2010. Gibberellin signalling - new opportunities for crop management. Outlooks on Pest Management. 21 (6), pp. 268-273. https://doi.org/10.1564/21Dec05

Gibberellin 3-oxidases in developing embryos of the southern wild cucumber, Marah macrocarpus

A - Papers appearing in refereed journals

Ward, D. A., Macmillan, J., Gong, F., Phillips, A. L. and Hedden, P. 2010. Gibberellin 3-oxidases in developing embryos of the southern wild cucumber, Marah macrocarpus. Phytochemistry. 71, pp. 2010-2018. https://doi.org/10.1016/j.phytochem.2010.09.015

A combined 1H nuclear magnetic resonance and electrospray ionization-mass spectrometry analysis to understand the basal metabolism of plant-pathogenic Fusarium spp

A - Papers appearing in refereed journals

Lowe, R. G. T., Allwood, J. W., Galster, A. M., Urban, M., Daudi, A., Canning, G., Ward, J. L., Beale, M. H. and Hammond-Kosack, K. E. 2010. A combined 1H nuclear magnetic resonance and electrospray ionization-mass spectrometry analysis to understand the basal metabolism of plant-pathogenic Fusarium spp. Molecular Plant-Microbe Interactions - MPMI. 23 (12), pp. 1605-1618. https://doi.org/10.1094/MPMI-04-10-0092

Bolting and flowering control in sugar beet: relationships and effects of gibberellin, the bolting gene B and vernalization

A - Papers appearing in refereed journals

Mutasa-Gottgens, E. S., Qi, A., Zhang, W., Schulze-Buxloh, G., Jennings, A., Hohmann, U., Muller, A. E. and Hedden, P. 2010. Bolting and flowering control in sugar beet: relationships and effects of gibberellin, the bolting gene B and vernalization. AoB Plants. 2010, p. plq012. https://doi.org/10.1093/aobpla/plq012

Functional analysis of folate polyglutamylation and its essential role in plant metabolism and development

A - Papers appearing in refereed journals

Mehrshahi, P., Gonzalez-Jorge, S., Akhtar, T. A., Ward, J. L., Santoyo-Castelazo, A., Marcus, S. E., Lara-Nunez, A., Ravanel, S., Hawkins, N. D., Beale, M. H., Barrett, D. A., Knox, J. P., Gregory, J. F. Iii, Hanson, A. D., Bennett, M. J. and Dellapenna, D. 2010. Functional analysis of folate polyglutamylation and its essential role in plant metabolism and development. The Plant Journal. 64, pp. 267-279. https://doi.org/10.1111/j.1365-313X.2010.04336.x

The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato

A - Papers appearing in refereed journals

Ward, J. L., Forcat, S., Beckmann, M., Bennett, M., Miller, S. J., Baker, J. M., Hawkins, N. D., Vermeer, C. P., Lu, C., Lin, W., Truman, W. M., Beale, M. H., Draper, J., Mansfield, J. W. and Grant, M. 2010. The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. The Plant Journal. 63 (3), pp. 443-457. https://doi.org/10.1111/j.1365-313X.2010.04254.x

Gibberellin biosynthesis and gibberellin oxidase activities in Fusarium sacchari, Fusarium konzum and Fusarium subglutinans strains

A - Papers appearing in refereed journals

Troncoso, C., Gonzalez, X., Bomke, C., Tudzynski, B., Gong, F., Hedden, P. and Rojas, M. C. 2010. Gibberellin biosynthesis and gibberellin oxidase activities in Fusarium sacchari, Fusarium konzum and Fusarium subglutinans strains. Phytochemistry. 71, pp. 1322-1331. https://doi.org/10.1016/j.phytochem.2010.05.006

Enhancement of plant metabolite fingerprinting by machine learning

A - Papers appearing in refereed journals

Scott, I. M., Vermeer, C. P., Liakata, M., Corol, D. I., Ward, J. L., Lin, W., Johnson, H. E., Whitehead, L., Kular, B., Baker, J. M., Walsh, S., Dave, A., Larson, T. R., Graham, I. A., Wang, T. L., King, R. D., Draper, J. and Beale, M. H. 2010. Enhancement of plant metabolite fingerprinting by machine learning. Plant Physiology. 153, pp. 1506-1520. https://doi.org/10.1104/pp.109.150524

An inter-laboratory comparison demonstrates that [1H]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection

A - Papers appearing in refereed journals

Ward, J. L., Baker, J. M., Miller, S. J., Deborde, C., Maucourt, M., Biais, B., Rolin, D., Moing, A., Moco, S., Vervoort, J., Lommen, A., Schafer, H., Humpfer, E. and Beale, M. H. 2010. An inter-laboratory comparison demonstrates that [1H]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection. Metabolomics. 6, pp. 263-273. https://doi.org/10.1007/s11306-010-0200-4

Phenolic acids

B - Book chapters etc edited externally

Li, L., Harflett, C. and Beale, M. H. 2010. Phenolic acids. in: Shewry, P. R. and Ward, J. L. (ed.) HEALTHGRAIN methods: analysis of bioactive components in small grain cereals American Association of Cereal Chemists (AACC), St Paul, MN. pp. 41-52

System-wide molecular evidence for phenotypic buffering in Arabidopsis

A - Papers appearing in refereed journals

Fu, J., Keurentjes, J. J. B., Bouwmeester, H., America, T., Verstappen, F. W. A., Ward, J. L., Beale, M. H., De Vos, R. C. H., Dijkstra, M., Scheltema, R. A., Johannes, F., Koornneef, M., Vreugdenhil, D., Breitling, R. and Jansen, R. C. 2009. System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nature Genetics. 41, pp. 166-167. https://doi.org/10.1038/ng.308

Sulphur nutrition differentially affects the distribution of asparagine in wheat grain

A - Papers appearing in refereed journals

Shewry, P. R., Zhao, F-J., Gowa, G. B., Hawkins, N. J., Ward, J. L., Beale, M. H., Halford, N. G., Parry, M. A. J. and Abecassis, J. 2009. Sulphur nutrition differentially affects the distribution of asparagine in wheat grain. Journal of Cereal Science. 50, pp. 407-409. https://doi.org/10.1016/j.jcs.2009.07.001

Abscisic acid levels in tomato ovaries are regulated by LeNCED1 and SlCYP707A1

A - Papers appearing in refereed journals

Nitsch, L. M. C., Oplaat, C., Feron, R., Ma, Q., Wolters-Arts, M., Hedden, P., Mariani, C. and Vriezen, W. H. 2009. Abscisic acid levels in tomato ovaries are regulated by LeNCED1 and SlCYP707A1. Planta. 229, pp. 1335-1346. https://doi.org/10.1007/s00425-009-0913-7

Drought stress increases the production of 5-hydroxynorvaline in two C4 grasses

A - Papers appearing in refereed journals

Carmo-Silva, A. E., Keys, A. J., Beale, M. H., Ward, J. L., Baker, J. M., Hawkins, N. D., Arrabaca, M. C. and Parry, M. A. J. 2009. Drought stress increases the production of 5-hydroxynorvaline in two C4 grasses. Phytochemistry. 70, pp. 664-671. https://doi.org/10.1016/j.phytochem.2009.03.001

Gibberellin as a factor in floral regulatory networks

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S. and Hedden, P. 2009. Gibberellin as a factor in floral regulatory networks. Journal of Experimental Botany. 60, pp. 1979-1989. https://doi.org/10.1093/jxb/erp040

Modification of gibberellin signalling (metabolism and signal transduction) in sugar beet: analysis of potential targets for crop improvement

A - Papers appearing in refereed journals

Mutasa-Göttgens, E. S., Qi, A., Mathews, A. M., Thomas, S. G., Phillips, A. L. and Hedden, P. 2009. Modification of gibberellin signalling (metabolism and signal transduction) in sugar beet: analysis of potential targets for crop improvement. Transgenic Research. 18, pp. 301-308. https://doi.org/10.1007/s11248-008-9211-6

Metabolomic and phenotypic analyses of Fusarium graminearum wild-type and mutant strains

C2 - Non-edited contributions to conferences

Urban, M., Lowe, R., Allwood, W., Ward, J. L., Beale, M. H. and Hammond-Kosack, K. E. 2008. Metabolomic and phenotypic analyses of Fusarium graminearum wild-type and mutant strains.

Loss of gibberellin production in Fusarium verticillioides (Gibberella fujikuroi MP-A) is due to a deletion in the gibberellic acid gene cluster

A - Papers appearing in refereed journals

Bomke, C., Rojas, M. C., Hedden, P. and Tudzynski, B. 2008. Loss of gibberellin production in Fusarium verticillioides (Gibberella fujikuroi MP-A) is due to a deletion in the gibberellic acid gene cluster. Applied and Environmental Microbiology. 74, pp. 7790-7801. https://doi.org/10.1128/AEM.01819-08

Expression profiling of potato germplasm differentiated in quality traits leads to the identification of candidate flavour and texture genes

A - Papers appearing in refereed journals

Ducreux, L. J. M., Morris, W. L., Prosser, I. M., Morris, J. A., Beale, M. H., Wright, F., Shepherd, T., Bryan, G. J., Hedley, P. E. and Taylor, M. A. 2008. Expression profiling of potato germplasm differentiated in quality traits leads to the identification of candidate flavour and texture genes. Journal of Experimental Botany. 59, pp. 4219-4231. https://doi.org/10.1093/jxb/ern264

Establishing substantial equivalence: metabolomics

B - Book chapters etc edited externally

Beale, M. H., Ward, J. L. and Baker, J. M. 2008. Establishing substantial equivalence: metabolomics. in: Shewry, P. R. and Jones, H. D. (ed.) Transgenic wheat, barley and oats. Methods in molecular biology, vol.478 Humana Press, New York. pp. 289-303

Gibberellins close the lid

G - Articles in popular magazines and other technical publications

Hedden, P. 2008. Gibberellins close the lid. Nature. 456 (27 November), pp. 455-456. https://doi.org/10.1038/456455a

Genetic analysis reveals that C19-GA 2-oxidation is a major gibberellin inactivation pathway in Arabidopsis

A - Papers appearing in refereed journals

Rieu, I., Eriksson, S., Powers, S. J., Gong, F., Griffiths, J., Woolley, L., Benlloch, R., Nilsson, O., Thomas, S. G., Hedden, P. and Phillips, A. L. 2008. Genetic analysis reveals that C19-GA 2-oxidation is a major gibberellin inactivation pathway in Arabidopsis. The Plant Cell. 20, pp. 2420-2436. https://doi.org/10.1105/tpc.108.058818

Ectopic expression of soybean leghemoglobin in chloroplasts impairs gibberellin biosynthesis and induces dwarfism in transgenic potato plants

A - Papers appearing in refereed journals

Bonna, A. L., Chaparro-Giraldo, A., Appezzato-Da-Gloria, B., Hedden, P. and Silva-Filho, M. C. 2008. Ectopic expression of soybean leghemoglobin in chloroplasts impairs gibberellin biosynthesis and induces dwarfism in transgenic potato plants. Molecular Breeding. 22, pp. 613-618. https://doi.org/10.1007/s11032-008-9203-5

Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant

A - Papers appearing in refereed journals

De Grauwe, L., Chaerle, L., Dugardeyn, J., Decat, J., Rieu, I., Vriezen, W. H., Moritz, T., Beemster, G. T. S., Phillips, A. L., Harberd, N. P., Hedden, P. and Van Der Straeten, D. 2008. Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant. New Phytologist. 177 (2), pp. 128-141. https://doi.org/10.1111/j.1469-8137.2007.02263.x

Co-ordinated expression of amino acid metabolism in response to N and S deficiency during wheat grain filling

A - Papers appearing in refereed journals

Howarth, J. R., Parmar, S., Jones, J., Shepherd, C. E., Corol, D. I., Galster, A. M., Hawkins, N. D., Miller, S. J., Baker, J. M., Verrier, P. J., Ward, J. L., Beale, M. H., Barraclough, P. B. and Hawkesford, M. J. 2008. Co-ordinated expression of amino acid metabolism in response to N and S deficiency during wheat grain filling. Journal of Experimental Botany. 59, pp. 3675-3689. https://doi.org/10.1093/jxb/ern218

Adopting an integrative systems biology approach to study root growth and development

C2 - Non-edited contributions to conferences

Bennett, M., French, A., Hodgman, C., Hedden, P., Holman, T., Middleton, A., King, J., Owen, M., Pridmore, T., Swarup, R., Thomas, S. G., Ubeda-Tomas, S. and Wilson, M. 2008. Adopting an integrative systems biology approach to study root growth and development. https://doi.org/10.1016/j.cbpa.2008.04.022

The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism

A - Papers appearing in refereed journals

Achard, P., Gong, F., Cheminant, S., Alioua, M., Hedden, P. and Genschik, P. 2008. The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism. The Plant Cell. 20, pp. 2117-2129. https://doi.org/10.1105/tpc.108.058941

Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola

A - Papers appearing in refereed journals

Bomke, C., Rojas, M. C., Gong, F., Hedden, P. and Tudzynski, B. 2008. Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola. Applied and Environmental Microbiology. 74, pp. 5325-5339. https://doi.org/10.1128/AEM.00694-08

The sensitivity of photosynthesis to phosphorus deficiency differs between C3 and C4 tropical grasses

A - Papers appearing in refereed journals

Ghannoum, O., Paul, M. J., Ward, J. L., Beale, M. H., Corol, D. I. and Conroy, J. P. 2008. The sensitivity of photosynthesis to phosphorus deficiency differs between C3 and C4 tropical grasses. Functional Plant Biology. 35, pp. 213-221. https://doi.org/10.1071/FP07256

Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis

A - Papers appearing in refereed journals

Ubeda-Tomas, S., Swarup, R., Coates, J., Swarup, K., Laplaze, L., Beemster, G. T. S., Hedden, P., Bhalerao, B. and Bennett, M. J. 2008. Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis. Nature Cell Biology. 10, pp. 625-628. https://doi.org/10.1038/ncb1726

Influence of electron transport proteins on the reactions catalyzed by Fusarium fujikuroi gibberellin monooxygenases

A - Papers appearing in refereed journals

Troncoso, C., Carcamo, J., Hedden, P., Tudzynski, B. and Rojas, M. C. 2008. Influence of electron transport proteins on the reactions catalyzed by Fusarium fujikuroi gibberellin monooxygenases. Phytochemistry. 69, pp. 672-683. https://doi.org/10.1016/j.phytochem.2007.08.026

The gibberellin biosynthetic genes AtGA20ox1 and AtGA20ox2 act, partially redundantly, to promote growth and development throughout the Arabidopsis lifecycle

A - Papers appearing in refereed journals

Rieu, I., Ruiz-Rivero, O., Fernandez-Garcia, N., Griffiths, J., Powers, S. J., Gong, F., Linhartova, T., Eriksson, S., Nilsson, O., Thomas, S. G., Phillips, A. L. and Hedden, P. 2008. The gibberellin biosynthetic genes AtGA20ox1 and AtGA20ox2 act, partially redundantly, to promote growth and development throughout the Arabidopsis lifecycle. The Plant Journal. 53 (3), pp. 488-504. https://doi.org/10.1111/j.1365-313X.2007.03356.x

Over-expression of a gibberellin 2-oxidase gene from Phaseolus coccineus L. enhances gibberellin inactivation and induces dwarfism in Solanum species

A - Papers appearing in refereed journals

Dijkstra, C., Adams, E., Bhattacharya, A., Page, A. F., Anthony, P., Kourmpetli, S., Power, J. B., Lowe, K. C., Thomas, S. G., Hedden, P., Phillips, A. L. and Davey, M. R. 2008. Over-expression of a gibberellin 2-oxidase gene from Phaseolus coccineus L. enhances gibberellin inactivation and induces dwarfism in Solanum species. Plant Cell Reports. 27, pp. 463-470. https://doi.org/10.1007/s00299-007-0471-z

Genetic modification of plant stature by manipulation of gibberellin metabolism: an alternative to chemical growth regulators

C2 - Non-edited contributions to conferences

Bhattacharya, A., Davey, M., Power, B., Ward, D. A., Phillips, A. L. and Hedden, P. 2007. Genetic modification of plant stature by manipulation of gibberellin metabolism: an alternative to chemical growth regulators. https://doi.org/10.1016/j.cbpa.2007.01.623

Ethylene-induced Arabidopsis hypocotyl elongation is dependent on but not mediated by gibberellins

A - Papers appearing in refereed journals

Vandenbussche, F., Vancompernolle, B., Rieu, I., Ahmad, M., Phillips, A. L., Moritz, T., Hedden, P. and Van Der Straeten, D. 2007. Ethylene-induced Arabidopsis hypocotyl elongation is dependent on but not mediated by gibberellins. Journal of Experimental Botany. 58, pp. 4269-4281. https://doi.org/10.1093/jxb/erm288

Phenotypic and metabolomic analyses of the Fusarium graminearum SNF1 mutant

C2 - Non-edited contributions to conferences

Urban, M., Antoniw, J. F., Allwood, W., Beacham, A., Ward, J. L., Beale, M. H. and Hammond-Kosack, K. E. 2007. Phenotypic and metabolomic analyses of the Fusarium graminearum SNF1 mutant. Abstracts 13th International Congress on Molecular Plant-Microbe Interactions, Sorrento, 21-27 July 2007 . pp. 212

Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat

A - Papers appearing in refereed journals

Appleford, N. E., Wilkinson, M. D., Ma, Q., Evans, D. J., Stone, M. C., Pearce, S. P., Powers, S. J., Thomas, S. G., Jones, H. D., Phillips, A. L., Hedden, P. and Lenton, J. R. 2007. Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat. Journal of Experimental Botany. 58, pp. 3213-3226. https://doi.org/10.1093/jxb/erm166

Proposed minimum reporting standards for chemical analysis. Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)

A - Papers appearing in refereed journals

Sumner, L. W., Amberg, A., Barrett, D., Beale, M. H., Beger, R., Daykin, C. A., Fan, T. W-M., Fiehn, O., Goodacre, R., Griffin, J. L., Hankemeier, T., Hardy, N., Harnly, J., Higashi, R., Kopka, J., Lane, A. N., Lindon, J. C., Marriott, P., Nicholls, A. W., Reily, M. D., Thaden, J. J. and Viant, M. R. 2007. Proposed minimum reporting standards for chemical analysis. Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics. 3 (3), pp. 211-221. https://doi.org/10.1007/s11306-007-0082-2

DON mycotoxin biosynthesis by Fusarium species, a metabolomics perspective

C2 - Non-edited contributions to conferences

Lowe, R., Allwood, J. W., Urban, M., Beale, M. H., Ward, J. L. and Hammond-Kosack, K. E. 2007. DON mycotoxin biosynthesis by Fusarium species, a metabolomics perspective. Abstracts BSPP Presidential Meeting 2007: Attack and Defence in Plant Disease, Bath, 12-14 September 2007 . pp. 64

Reciprocal influence of ethylene and gibberellins on response-gene expression in Arabadopsis thaliana

A - Papers appearing in refereed journals

De Grauwe, L., Vriezen, W. H., Bertrand, S., Phillips, A. L., Vidal, A. M., Hedden, P. and Van Der Straeten, D. 2007. Reciprocal influence of ethylene and gibberellins on response-gene expression in Arabadopsis thaliana. Planta. 226, pp. 485-498. https://doi.org/10.1007/s00425-007-0499-x

The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism

A - Papers appearing in refereed journals

Dai, M., Zhao, Y., Ma, Q., Hu, Y., Hedden, P., Zhang, Q. and Zhou, D-X. 2007. The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism. Plant Physiology. 144, pp. 121-133. https://doi.org/10.1104/pp.107.096586

The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes

A - Papers appearing in refereed journals

Achard, P., Baghour, M., Chapple, A., Hedden, P., Van Der Straeten, D., Genschik, P., Moritz, T. and Harberd, N. P. 2007. The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes. Proceedings of the National Academy of Sciences. 104, pp. 6484-6489. https://doi.org/10.1073/pnas.0610717104

Are GM and conventionally bred cereals really different?

A - Papers appearing in refereed journals

Shewry, P. R., Baudo, M., Lovegrove, A., Powers, S. J., Napier, J. A., Ward, J. L., Baker, J. M. and Beale, M. H. 2007. Are GM and conventionally bred cereals really different? Trends in Food Science and Technology. 18, pp. 201-209. https://doi.org/10.1016/j.tifs.2006.12.010

Recent applications of NMR spectroscopy in plant metabolomics

A - Papers appearing in refereed journals

Ward, J. L., Baker, J. M. and Beale, M. H. 2007. Recent applications of NMR spectroscopy in plant metabolomics. The FEBS Journal. 274 (5), pp. 1126-1131. https://doi.org/10.1111/j.1742-4658.2007.05675.x

Transcriptional adaptation of Mycosphaerella graminicola to programmed cell death (PCD) of its susceptible wheat host

A - Papers appearing in refereed journals

Keon, J. P. R., Antoniw, J. F., Carzaniga, R., Deller, S., Ward, J. L., Baker, J. M., Beale, M. H., Hammond-Kosack, K. E. and Rudd, J. J. 2007. Transcriptional adaptation of Mycosphaerella graminicola to programmed cell death (PCD) of its susceptible wheat host. Molecular Plant-Microbe Interactions - MPMI. 20 (2), pp. 178-193. https://doi.org/10.1094/MPMI-20-2-0178

Gibberellin metabolism and signal transduction

B - Book chapters etc edited externally

Hedden, P. and Thomas, S. G. 2006. Gibberellin metabolism and signal transduction. in: Hedden, P. and Thomas, S. G. (ed.) In: Annual Plant Reviews Volume 24: Plant Hormone Signaling (Chapter 6) Blackwell Publishing Oxford.

Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis

A - Papers appearing in refereed journals

Griffiths, J., Murase, K., Rieu, I., Zentella, R., Zhang, Z-L., Powers, S. J., Gong, F., Phillips, A. L., Hedden, P., Sun, T-P. and Thomas, S. G. 2006. Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis. The Plant Cell. 18 (12), pp. 3399-3414. https://doi.org/10.1105/tpc.106.047415

The POLARIS peptide of Arabidopsis regulates auxin transport and root growth via effects on ethylene signaling

A - Papers appearing in refereed journals

Chilley, P. M., Casson, S. A., Tarkowski, P., Hawkins, N. D., Wang, K. L-C., Hussey, P. J., Beale, M. H., Ecker, J. R., Sandberg, G. J. and Lindsey, K. 2006. The POLARIS peptide of Arabidopsis regulates auxin transport and root growth via effects on ethylene signaling. The Plant Cell. 18, pp. 3058-3072. https://doi.org/10.1105/tpc.106.040790

Transcriptional adaptation of Mycosphaerella graminicola to programmed cell death (PCD) of its susceptible wheat host

C2 - Non-edited contributions to conferences

Keon, J. P. R., Antoniw, J. F., Carzaniga, R., Deller, S., Ward, J. L., Baker, J. M., Beale, M. H., Hammond-Kosack, K. E. and Rudd, J. J. 2006. Transcriptional adaptation of Mycosphaerella graminicola to programmed cell death (PCD) of its susceptible wheat host. Abstracts 3rd COGEME Interest Group Meeting, Manchester, 7-8 November 2006 .

Transcriptional regulation of gibberellin metabolism genes by auxin signaling in Arabidopsis

A - Papers appearing in refereed journals

Frigerio, M., Alabadi, D., Perez-Gomez, J., Garcia-Carcel, L., Phillips, A. L., Hedden, P. and Blazquez, M. A. 2006. Transcriptional regulation of gibberellin metabolism genes by auxin signaling in Arabidopsis. Plant Physiology. 142, pp. 553-563. https://doi.org/10.1104/pp.106.084871

Overexpression of a bacterial 1-deoxy-D-xylulose 5-phosphate synthase gene in potato tubers perturbs the isoprenoid metabolic network: implications for the control of the tuber life cycle

A - Papers appearing in refereed journals

Morris, W. L., Ducreux, L. J. M., Hedden, P., Millam, S. and Taylor, M. A. 2006. Overexpression of a bacterial 1-deoxy-D-xylulose 5-phosphate synthase gene in potato tubers perturbs the isoprenoid metabolic network: implications for the control of the tuber life cycle. Journal of Experimental Botany. 57, pp. 3007-3018. https://doi.org/10.1093/jxb/erl061

Cloning and functional characterisation of a cis -muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene

A - Papers appearing in refereed journals

Prosser, I. M., Adams, R. J., Beale, M. H., Hawkins, N. D., Phillips, A. L., Pickett, J. A. and Field, L. M. 2006. Cloning and functional characterisation of a cis -muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene. Phytochemistry. 67, pp. 1564-1571. https://doi.org/10.1016/j.phytochem.2005.06.012

Long-term submergence-induced elongation in Rumex palustris requires abscisic acid-dependent biosynthesis of gibberellin1

A - Papers appearing in refereed journals

Benschop, J. J., Bou, J., Peeters, A. J. M., Wagemaker, N., Guhl, K., Ward, D. A., Hedden, P., Moritz, T. and Voesenek, L. A. C. J. 2006. Long-term submergence-induced elongation in Rumex palustris requires abscisic acid-dependent biosynthesis of gibberellin1. Plant Physiology. 141, pp. 1644-1652. https://doi.org/10.1104/pp.106.082636

Aphid alarm pheromone produced by transgenic plants affects aphid and parasitoid behavior

A - Papers appearing in refereed journals

Beale, M. H., Birkett, M. A., Bruce, T. J. A., Chamberlain, K., Field, L. M., Huttly, A. K., Martin, J. L., Parker, R., Phillips, A. L., Pickett, J. A., Prosser, I. M., Shewry, P. R., Smart, L. E., Wadhams, L. J., Woodcock, C. M. and Zhang, Y. 2006. Aphid alarm pheromone produced by transgenic plants affects aphid and parasitoid behavior. Proceedings of the National Academy of Sciences. 103, pp. 10509-10513. https://doi.org/10.1073/pnas.0603998103

Strigolactones in chemical ecology: waste products or vital allelochemicals?

A - Papers appearing in refereed journals

Humphrey, A. J., Galster, A. M. and Beale, M. H. 2006. Strigolactones in chemical ecology: waste products or vital allelochemicals? Natural Product Reports. 23, pp. 592-614. https://doi.org/10.1039/b512776a

A metabolomic study of substantial equivalence of field-grown genetically modified wheat

A - Papers appearing in refereed journals

Baker, J. M., Hawkins, N. D., Ward, J. L., Lovegrove, A., Napier, J. A., Shewry, P. R. and Beale, M. H. 2006. A metabolomic study of substantial equivalence of field-grown genetically modified wheat. Plant Biotechnology Journal. 4 (4), pp. 381-392. https://doi.org/10.1111/j.1467-7652.2006.00197.x

Function and transcript analysis of gibberellin-biosynthetic enzymes in wheat

A - Papers appearing in refereed journals

Appleford, N. E. J., Evans, D. J., Lenton, J. R., Gaskin, P., Croker, S. J., Devos, K. M., Phillips, A. L. and Hedden, P. 2006. Function and transcript analysis of gibberellin-biosynthetic enzymes in wheat. Planta. 223, pp. 568-582. https://doi.org/10.1007/s00425-005-0104-0

Strigol: biogenesis and physiological activity

A - Papers appearing in refereed journals

Humphrey, A. J. and Beale, M. H. 2006. Strigol: biogenesis and physiological activity. Phytochemistry. 67, pp. 636-640. https://doi.org/10.1016/j.phytochem.2005.12.026

Enhanced seed phytosterol accumulation through expression of a modified HMG-CoA reductase

A - Papers appearing in refereed journals

Hey, S. J., Powers, S. J., Beale, M. H., Hawkins, N. D., Ward, J. L. and Halford, N. G. 2006. Enhanced seed phytosterol accumulation through expression of a modified HMG-CoA reductase. Plant Biotechnology Journal. 4 (2), pp. 219-229. https://doi.org/10.1111/j.1467-7652.2005.00174.x

Chickpea wilt: identification and toxicity of 8-0 -methyl-fusarubin from Fusarium acutatum

A - Papers appearing in refereed journals

Gopalakrishnan, S., Beale, M. H., Ward, J. L. and Strange, R. N. 2005. Chickpea wilt: identification and toxicity of 8-0 -methyl-fusarubin from Fusarium acutatum. Phytochemistry. 66, pp. 1536-1539. https://doi.org/10.1016/j.phytochem.2005.04.037

Restoration of gibberellin production in Fusarium proliferatum by functional complementation of enzymatic blocks

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Hopkins, P. and Tudzynski, B. 2005. Restoration of gibberellin production in Fusarium proliferatum by functional complementation of enzymatic blocks. Applied and Environmental Microbiology. 71, pp. 6014-6025.

Purification and kinetic studies of recombinant gibberellin dioxygenases

A - Papers appearing in refereed journals

Lester, D. R., Phillips, A. L., Hedden, P. and Andersson, I. 2005. Purification and kinetic studies of recombinant gibberellin dioxygenases. BMC Plant Biology. 5:19. https://doi.org/10.1186/1471-2229-5-19

Bioassay-led isolation of Myrothecium verrucaria and verrucarin A as germination inhibitors of Orobanche crenata

A - Papers appearing in refereed journals

El-Kassas, R., Karam El-Din, Z., Beale, M. H., Ward, J. L. and Strange, R. N. 2005. Bioassay-led isolation of Myrothecium verrucaria and verrucarin A as germination inhibitors of Orobanche crenata. Weed Research. 45 (3), pp. 212-219. https://doi.org/10.1111/j.1365-3180.2005.00448.x

Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4 , of the gibberellic acid gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D)

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Gaskin, P., Hopkins, P. and Tudzynski, B. 2005. Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4 , of the gibberellic acid gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D). Applied and Environmental Microbiology. 71, pp. 1462-1472.

Modification of gibberellin biosynthesis in the grafted apple scion allows control of tree height independent of the rootstock

A - Papers appearing in refereed journals

Bulley, S. M., Wilson, F. M., Hedden, P., Phillips, A. L., Croker, S. J. and James, D. J. 2005. Modification of gibberellin biosynthesis in the grafted apple scion allows control of tree height independent of the rootstock. Plant Biotechnology Journal. 3 (2), pp. 215-223. https://doi.org/10.1111/j.1467-7652.2005.00119.x

The auxin transport inhibitor response 3 (tir3) allele of BIG and auxin transport inhibitors affect the gibberellin status of Arabidopsis

A - Papers appearing in refereed journals

Desgagne-Penix, I., Eakanunkul, S., Coles, J. P., Phillips, A. L., Hedden, P. and Sponsel, V. 2005. The auxin transport inhibitor response 3 (tir3) allele of BIG and auxin transport inhibitors affect the gibberellin status of Arabidopsis. The Plant Journal. 41 (2), pp. 231-242. https://doi.org/10.1111/j.1365-313X.2004.02287.x

Analysis of detergent-resistant membranes in Arabidopsis. Evidence for plasma membrane lipid rafts

A - Papers appearing in refereed journals

Borner, G. H. H., Sherrier, D. J., Weimar, T., Michaelson, L. V., Hawkins, N. D., Macaskill, A., Napier, J. A., Beale, M. H., Lilley, K. S. and Dupree, P. 2005. Analysis of detergent-resistant membranes in Arabidopsis. Evidence for plasma membrane lipid rafts. Plant Physiology. 137 (1), pp. 104-116. https://doi.org/10.1104/pp.104.053041

Gibberellin biosynthesis and inactivation

B - Book chapters etc edited externally

Sponsel, V. M. and Hedden, P. 2004. Gibberellin biosynthesis and inactivation. in: Davies, P. J. (ed.) Plant hormones - biosynthesis, signal transduction, action! 3rd ed. Kluwer Academic Publishers, Dordrecht, Netherlands. pp. 63-94

Reduced stature plants (Patent application)

H2 - Patents applied for

Phillips, A. L., Hedden, P., Bulley, S. M. W. and James, D. J. 2004. Reduced stature plants (Patent application).

Metabolite profiling of GM plants: the importance of robust experimental design and execution

B - Book chapters etc edited externally

Lewis, J., Baker, J. M., Beale, M. H. and Ward, J. L. 2004. Metabolite profiling of GM plants: the importance of robust experimental design and execution. in: Stiekema, W. J., Atanassov, A. and Nap, J. P. H. (ed.) Genomics for biosafety in plant biotechnology IOS Press, Amsterdam. pp. 47-57

Potential of metabolomics as a functional genomics tool

A - Papers appearing in refereed journals

Bino, R. J., Hall, R. D., Fiehn, O., Kopka, J., Saito, K., Draper, J., Nikolau, B. J., Mendes, P., Roessner-Tunali, U., Beale, M. H., Trethewey, R. N., Lange, B. M., Wurtele, E. S. and Sumner, L. W. 2004. Potential of metabolomics as a functional genomics tool. Trends in Plant Science. 9, pp. 418-425.

Lipid utilization, gluconeogenesis and seedling growth in Arabidopsis mutants lacking the glyoxylate cycle enzyme malate synthase

A - Papers appearing in refereed journals

Cornah, J. E., Germain, V., Ward, J. L., Beale, M. H. and Smith, S. M. 2004. Lipid utilization, gluconeogenesis and seedling growth in Arabidopsis mutants lacking the glyoxylate cycle enzyme malate synthase. Journal of Biological Chemistry. 279 (41), pp. 42916-42923. https://doi.org/10.1074/jbc.M407380200

Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development

A - Papers appearing in refereed journals

Naested, H., Holm, A., Jenkins, T., Nielsen, H. B., Harris, C. A., Beale, M. H., Andersen, M., Mant, A., Scheller, H., Camara, B., Mattsson, O. and Munday, J. 2004. Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development. Journal Of Cell Science. 117 (20), pp. 4807-4818. https://doi.org/10.1242/jcs.01360

Enantiospecific (+)- and (-)-germacrene D synthases, cloned from goldenrod, reveal a functionally active variant of the universal isoprenoid-biosynthesis aspartate-rich motif

A - Papers appearing in refereed journals

Prosser, I., Altug, I. G., Phillips, A. L., Konig, W. A., Bouwmeester, H. J. and Beale, M. H. 2004. Enantiospecific (+)- and (-)-germacrene D synthases, cloned from goldenrod, reveal a functionally active variant of the universal isoprenoid-biosynthesis aspartate-rich motif. Archives of Biochemistry and Biophysics. 432 (2), pp. 136-144. https://doi.org/10.1016/j.abb.2004.06.030

Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi

A - Papers appearing in refereed journals

Rojas, M. C., Urrutia, O., Cruz, C., Gaskin, P., Tudzynski, B. and Hedden, P. 2004. Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi. Phytochemistry. 65, pp. 821-830.

The NADPH-cytochrome P450 reductase gene from Gibberella fujikuroi is essential for gibberellin biosynthesis

A - Papers appearing in refereed journals

Malonek, S., Rojas, M. C., Hedden, P., Gaskin, P., Hopkins, P. and Tudzynski, B. 2004. The NADPH-cytochrome P450 reductase gene from Gibberella fujikuroi is essential for gibberellin biosynthesis. Journal of Biological Chemistry. 279, pp. 25075-25084.

Gibberellins

B - Book chapters etc edited externally

Hedden, P. 2003. Gibberellins. in: Thomas, B., Murray, B. G. and Murphy, D. J. (ed.) Encyclopedia of applied plant sciences Academic Press Inc New York. pp. 1011-1019

Short cicuiting photorespiration

C2 - Non-edited contributions to conferences

Parry, M. A. J., Carvalho, J. F. C., Madgwick, P. J., Keys, A. J., Lea, P. J., Beale, M. H. and Ward, J. L. 2003. Short cicuiting photorespiration. Abstracts ASPB Annual Meeting Plant Biology 2003, Honolulu, 25-30 July 2003 . pp. Abs 379

Short circuiting photorespiration

C2 - Non-edited contributions to conferences

Parry, M. A. J., Madgwick, P. J., Keys, A. J., Carvalho, J. F. C., Lea, P. J., Beale, M. H. and Ward, J. L. 2003. Short circuiting photorespiration. Abstracts ASPB Annual Meeting Plant Biology 2003, Honolulu, 25-30 July 2003 . pp. Abs 18002

Production of high value chemicals in plants

B - Book chapters etc edited externally

Beale, M. H. and Napier, J. A. 2003. Production of high value chemicals in plants. in: Shewry, P. R., Lenton, J. R. and Anderson, H. M. (ed.) Long Ashton Research Station: one hundred years of science in support of agriculture Institute for Arable Crops Research (IACR) , Long Ashton Research Station (LARS), Bristol. pp. 284-290

Production and characterization of transgenic wheat with altered gibberellin catabolism

C2 - Non-edited contributions to conferences

Evans, D. J., Stone, M., Appleford, N. E. J., Wilkinson, M. D., Jones, H. D., Ma, Q., Croker, S. J., Phillips, A. L., Hedden, P. and Lenton, J. R. 2003. Production and characterization of transgenic wheat with altered gibberellin catabolism.

Controlling stature in apple trees by genetic modification of gibberellin biosynthesis

C2 - Non-edited contributions to conferences

Bulley, S. M. W., James, D. J., Phillips, A. L. and Hedden, P. 2003. Controlling stature in apple trees by genetic modification of gibberellin biosynthesis.

Molecular characterisation of the GA 20-oxidase-1 promoter from Arabidopsis : identification of cis-elements that mediate control of gene expression by gibberellins

C2 - Non-edited contributions to conferences

Ruiz, O., Coles, J., Hedden, P. and Phillips, A. L. 2003. Molecular characterisation of the GA 20-oxidase-1 promoter from Arabidopsis : identification of cis-elements that mediate control of gene expression by gibberellins.

Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively

A - Papers appearing in refereed journals

Tudzynski, B., Mihlan, M., Rojas, M. C., Linnemannstons, P., Gaskin, P. and Hedden, P. 2003. Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively. Journal of Biological Chemistry. 278, pp. 28635-28643.

Constructing dwarf rice

A - Papers appearing in refereed journals

Hedden, P. 2003. Constructing dwarf rice. Nature Biotechnology. 21 (8), pp. 873-874. https://doi.org/10.1038/nbt0803-873

The genes of the Green Revolution

A - Papers appearing in refereed journals

Hedden, P. 2003. The genes of the Green Revolution. Trends in Genetics. 19, pp. 5-9.

The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe

A - Papers appearing in refereed journals

Garton, S., Michaelson, L. V., Beaudoin, F., Beale, M. H. and Napier, J. A. 2003. The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe. FEBS Letters. 538, pp. 192-196.

Metabolic signalling: Role of SnRK1 in regulating sterol biosynthesis

C2 - Non-edited contributions to conferences

Hey, S. J., Beale, M. H., Mckibbin, R. S., Laurie, S. and Halford, N. G. 2003. Metabolic signalling: Role of SnRK1 in regulating sterol biosynthesis. Society for Experimental Biology Annual Main Meeting: 31st March–4th April 2002, Southampton, UK  . https://doi.org/10.1016/S1095-6433(03)00034-5

Interactions between plant hormone signalling and gibberellin biosynthesis

C2 - Non-edited contributions to conferences

Clark, N. R., Coles, J. P., Ruiz, O., Hedden, P. and Phillips, A. L. 2003. Interactions between plant hormone signalling and gibberellin biosynthesis.

Secondary metabolite signalling in host-parasitic plant interactions

A - Papers appearing in refereed journals

Bouwmeester, H. J., Matusova, R., Zhongkui, S. and Beale, M. H. 2003. Secondary metabolite signalling in host-parasitic plant interactions. Current Opinion in Plant Biology. 6, pp. 358-364.

Assessment of 1H NMR spectroscopy and multivariate analysis as a technique for metabolite fingerprinting of Arabidopsis thaliana

A - Papers appearing in refereed journals

Ward, J. L., Harris, C., Lewis, J. and Beale, M. H. 2003. Assessment of 1H NMR spectroscopy and multivariate analysis as a technique for metabolite fingerprinting of Arabidopsis thaliana. Phytochemistry. 62, pp. 949-957.

New approach to achieve tissue-specific transgene expression in plants

C2 - Non-edited contributions to conferences

Roden, L. C., Phillips, A. L., Hedden, P. and Mutasa-Göttgens, E. S. 2002. New approach to achieve tissue-specific transgene expression in plants. Abstracts 10th Plant, Animal and Microbe Genomes Conference, San Diego, 12-16 January 2002 .

Plant metabolomics: the missing link in functional genomics strategies

A - Papers appearing in refereed journals

Hall, R., Beale, M. H., Fiehn, O., Hardy, N., Sumner, N. and Bino, R. 2002. Plant metabolomics: the missing link in functional genomics strategies. The Plant Cell. 14, pp. 1437-1440. https://doi.org/10.1105/tpc.140720

The gibberellin pathway mediates KNOTTED1-type homeobox function in plants with different body plans

A - Papers appearing in refereed journals

Hay, A., Kaur, H., Phillips, A. L., Hedden, P., Hake, S. and Tsiantis, M. 2002. The gibberellin pathway mediates KNOTTED1-type homeobox function in plants with different body plans. Current Biology. 12, pp. 1557-1565. https://doi.org/10.1016/S0960-9822(02)01125-9

Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone

A - Papers appearing in refereed journals

Wong, J. H., Kim, Y-B., Ren, P-H., Cai, N., Cho, M-J., Hedden, P., Lemaux, P. G. and Buchanan, B. B. 2002. Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone. Proceedings of the National Academy of Sciences. 99 (25), pp. 16325-16330. https://doi.org/10.1073/pnas.212641999

Elemental sulfur and thiol accumulation in tomato and defense against a fungal vascular pathogen

A - Papers appearing in refereed journals

Williams, J. S., Hall, S. A., Hawkesford, M. J., Beale, M. H. and Cooper, R. M. 2002. Elemental sulfur and thiol accumulation in tomato and defense against a fungal vascular pathogen. Plant Physiology. 128, pp. 150-159.

The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase

A - Papers appearing in refereed journals

Tudzynski, B., Rojas, M. C., Gaskin, P. and Hedden, P. 2002. The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase. Journal of Biological Chemistry. 277, pp. 21246-21253.

Cloning and expression of sesquiterpene synthase genes from Lettuce (Lactuca sativa L.)

A - Papers appearing in refereed journals

Bennett, M. H., Mansfield, J. W., Lewis, M. J. and Beale, M. H. 2002. Cloning and expression of sesquiterpene synthase genes from Lettuce (Lactuca sativa L.). Phytochemistry. 60, pp. 255-261.

GARNet, the Genomic Arabidopsis Resource Network

A - Papers appearing in refereed journals

Beale, M. H., Dupree, P., Lilley, K., Beynon, J., Trick, M., Clarke, J., Bevan, M., Bancroft, I., Jones, J., May, S., Van De Sande, K. and Leyser, O. 2002. GARNet, the Genomic Arabidopsis Resource Network. Trends in Plant Science. 7, pp. 145-147.

(+)-(10R )-germacrene A synthase from goldenrod, Solidago canadensis ; cDNA isolation, bacterial expression and functional analysis

A - Papers appearing in refereed journals

Prosser, I. M., Phillips, A. L., Gittings, S., Lewis, M. J., Hooper, A. M., Pickett, J. A. and Beale, M. H. 2002. (+)-(10R )-germacrene A synthase from goldenrod, Solidago canadensis ; cDNA isolation, bacterial expression and functional analysis. Phytochemistry. 60, pp. 691-702.

Synthesis of (2E )-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids

A - Papers appearing in refereed journals

Ward, J. L. and Beale, M. H. 2002. Synthesis of (2E )-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids. Journal of the Chemical Society-Perkin Transactions 1. 2002, pp. 710-712.

Probing the mechanism of loss of carbon-20 in gibberellin biosynthesis. Synthesis of gibberellin 3alpha,20-hemiacetal and 19,20-lactol analogues and their metabolism by a recombinant GA 20-oxidase

A - Papers appearing in refereed journals

Ward, J. L., Gaskin, P., Brown, R. G. S., Jackson, G. S., Hedden, P., Phillips, A. L., Willis, C. L. and Beale, M. H. 2002. Probing the mechanism of loss of carbon-20 in gibberellin biosynthesis. Synthesis of gibberellin 3alpha,20-hemiacetal and 19,20-lactol analogues and their metabolism by a recombinant GA 20-oxidase. Journal of the Chemical Society-Perkin Transactions 1. 2002, pp. 232-241.

Gibberellin Biosynthesis in Plants and Fungi: A Case of Convergent Evolution?

A - Papers appearing in refereed journals

Hedden, P., Phillips, A. L., Rojas, M. C., Carrera, E. and Tudzynski, B. 2001. Gibberellin Biosynthesis in Plants and Fungi: A Case of Convergent Evolution? Journal of Plant Growth Regulation. 20 (4), pp. 319-331. https://doi.org/10.1007/s003440010037

Monooxygenases involved in GA12 and GA14 synthesis in Gibberella fujikuroi

A - Papers appearing in refereed journals

Urrutia, O., Hedden, P. and Rojas, M. C. 2001. Monooxygenases involved in GA12 and GA14 synthesis in Gibberella fujikuroi. Phytochemistry. 56, pp. 505-511.

The P450-4 gene of Gibberella fujikuroi encodes ent -kaurene oxidase in the gibberellin biosynthesis pathway

A - Papers appearing in refereed journals

Tudzynski, B., Hedden, P., Carrera, E. and Gaskin, P. 2001. The P450-4 gene of Gibberella fujikuroi encodes ent -kaurene oxidase in the gibberellin biosynthesis pathway. Applied and Environmental Microbiology. 67, pp. 3514-3522.

The P450-1 gene of Gibberella fujikuroi encodes a multifunctional enzyme in gibberellin biosynthesis

A - Papers appearing in refereed journals

Rojas, M. C., Hedden, P., Gaskin, P. and Tudzynski, B. 2001. The P450-1 gene of Gibberella fujikuroi encodes a multifunctional enzyme in gibberellin biosynthesis. Proceedings of the National Academy of Sciences. 98 (10), pp. 5838-5843. https://doi.org/10.1073/pnas.091096298

Production of dwarf lettuce by overexpressing a pumpkin gibberellin 20-oxidase gene

A - Papers appearing in refereed journals

Niki, T., Nishijima, T., Nakayama, M., Hisamatsu, T., Oyama-Okubo, N., Yamazaki, H., Hedden, P., Lange, T., Mander, L. T. and Koshioka, M. 2001. Production of dwarf lettuce by overexpressing a pumpkin gibberellin 20-oxidase gene. Plant Physiology. 126, pp. 965-972.

Workshop on Biochemistry and Molecular Biology of Gibberellins, Madrid, 27-29 March 2000

B - Book chapters etc edited externally

Hedden, P. 2000. Workshop on Biochemistry and Molecular Biology of Gibberellins, Madrid, 27-29 March 2000. in: Garcia-Martinez, J. L. (ed.) Instituto Juan March de Estudios e Investagaciones, Madrid. pp. 81pp

Hormone Engineering in Plants [La manipulation des hormones chez les plantes]

G - Articles in popular magazines and other technical publications

Hedden, P. and Phillips, A. L. 2000. Hormone Engineering in Plants [La manipulation des hormones chez les plantes]. Biofutur. 204, pp. 46-48. https://doi.org/10.1016/S0294-3506(00)80170-2

Effects of prohexadione-Ca on gibberellin levels in young apple shoots

C2 - Non-edited contributions to conferences

Croker, S. J., Hedden, P. and Rademacher, W. 2000. Effects of prohexadione-Ca on gibberellin levels in young apple shoots.

Gibberellin metabolism: new insights revealed by the genes

A - Papers appearing in refereed journals

Hedden, P. and Phillips, A. L. 2000. Gibberellin metabolism: new insights revealed by the genes. Trends in Plant Science. 5 (12), pp. 523-530. https://doi.org/10.1016/s1360-1385(00)01790-8

Gibberellins and seed development in maize. I. Evidence that gibberellin/ abscisic acid balance governs germination versus maturation pathways

A - Papers appearing in refereed journals

White, C. N., Proebsting, W. M., Hedden, P. and Rivin, . J. 2000. Gibberellins and seed development in maize. I. Evidence that gibberellin/ abscisic acid balance governs germination versus maturation pathways. Plant Physiology. 122, pp. 1081-1088.

Metabolite profiling of sesquiterpene lactones from Lactuca species

A - Papers appearing in refereed journals

Sessa, R. A., Bennett, M. H., Lewis, M. J., Mansfield, J. W. and Beale, M. H. 2000. Metabolite profiling of sesquiterpene lactones from Lactuca species. Journal of Biological Chemistry. 275, pp. 26877-26884.

Manipulation of hormone biosynthetic genes in transgenic plants

A - Papers appearing in refereed journals

Hedden, P. and Phillips, A. L. 2000. Manipulation of hormone biosynthetic genes in transgenic plants. Current Opinion in Biotechnology. 11, pp. 130-137.

Transformation and characterization of transgenic plants of Solanum dulcamara L. - incidence of transgene silencing

A - Papers appearing in refereed journals

Curtis, I. S., Power, J. B., Hedden, P., Phillips, A. L., Lowe, K. C., Ward, D. A. and Davey, M. R. 2000. Transformation and characterization of transgenic plants of Solanum dulcamara L. - incidence of transgene silencing. Annals of Botany. 86, pp. 63-71.

Induction of dwarfism in transgenic Solanum dulcamara by over-expression of a gibberellin 20-oxidase cDNA from pumpkin

A - Papers appearing in refereed journals

Curtis, I. S., Ward, D. A., Thomas, S. G., Phillips, A. L., Davey, M. R., Power, J. B., Lowe, K. C., Croker, S. J., Lewis, M. J., Magness, S. L. and Hedden, P. 2000. Induction of dwarfism in transgenic Solanum dulcamara by over-expression of a gibberellin 20-oxidase cDNA from pumpkin. The Plant Journal. 23, pp. 329-338.

Genetic Analysis of Gibberellin Biosynthesis

A - Papers appearing in refereed journals

Hedden, P. and Proebsting, W. M. 1999. Genetic Analysis of Gibberellin Biosynthesis. Plant Physiology. 119 (2), pp. 365-370. https://doi.org/10.1104/pp.119.2.365

Modification of gibberellin production and plant development in Arabidopsis by sense and antisense expression of gibberellin 20‐oxidase genes

A - Papers appearing in refereed journals

Coles, J. P., Phillips, A. L., Croker, S. J., García‐Lepe, R., Lewis , M. J. and Hedden, P. 1999. Modification of gibberellin production and plant development in Arabidopsis by sense and antisense expression of gibberellin 20‐oxidase genes. The Plant Journal. 17 (5), pp. 547-556. https://doi.org/10.1046/j.1365-313X.1999.00410.x

Molecular cloning and functional expression of gibberellin 2-oxidases, multifunctional enzymes involved in gibberellin deactivation

A - Papers appearing in refereed journals

Thomas, S. G., Phillips, A. L. and Hedden, P. 1999. Molecular cloning and functional expression of gibberellin 2-oxidases, multifunctional enzymes involved in gibberellin deactivation. Proceedings of the National Academy of Sciences. 96 (8), pp. 4698-4703. https://doi.org/10.1073/pnas.96.8.4698

Caged plant growth regulators

B - Book chapters etc edited externally

Allan, A. C., Ward, J. L., Beale, M. H. and Trewavas, A. J. 1998. Caged plant growth regulators. in: Marriott, G. (ed.) Methods in Enzymology Vol. 291. Caged Compounds Academic Press, San Diego.

Genetic engineering for bolting resistance

C1 - Edited contributions to conferences/learned societies

Van Roggen, P. M., Thomas, S. G., Hedden, P., Phillips, A. L., Debenham, G. B., Scott, R. W. and Mathews, A. M. 1997. Genetic engineering for bolting resistance. Proceedings 60th Congress of the Institut International de Recherches Betteravieres, Cambridge, July 1997 . pp. 571-574

Isolation and Expression of Three Gibberellin 20-Oxidase cDNA Clones from Arabidopsis

A - Papers appearing in refereed journals

Phillips, A. L., Ward, D. A., Uknes, S., Appleford, N. E. J., Lange, T., Huttly, A. K., Gaskin, P., Graebe, J. E. and Hedden, P. 1995. Isolation and Expression of Three Gibberellin 20-Oxidase cDNA Clones from Arabidopsis. Plant Physiology. 108 (3), pp. 1049-1057. https://doi.org/10.1104/pp.108.3.1049

Quantitative analysis of gibberellins by isotope dilution mass spectrometry: a comparison of the use of calibration curves, an isotope dilution fit program and arithmetical correction of isotope ratios

A - Papers appearing in refereed journals

Croker, S. J., Gaskin, P., Hedden, P., Macmillan, J. and Macneil, K. A. G. 1994. Quantitative analysis of gibberellins by isotope dilution mass spectrometry: a comparison of the use of calibration curves, an isotope dilution fit program and arithmetical correction of isotope ratios. Phytochemical Analysis. 5 (2), pp. 74-80. https://doi.org/10.1002/pca.2800050206

Effects of the triazole plant-growth retardant BAS 111¨ W on gibberellin levels in oilseed rape, Brassica napus

A - Papers appearing in refereed journals

Hedden, P., Croker, S. J., Rademacher, W. and Jung, J. 1989. Effects of the triazole plant-growth retardant BAS 111¨ W on gibberellin levels in oilseed rape, Brassica napus. Physiologia Plantarum. 75 (4), pp. 445-451. https://doi.org/10.1111/j.1399-3054.1989.tb05607.x

Synthesis and biological activity of an azido derivative of Paclobutrazol, an inhibitor of gibberelin biosynthesis.

A - Papers appearing in refereed journals

Hallahan, D. L., Heasman, A. P., Grossel, M. C., Quigley, R., Hedden, P. and Bowyer, J. R. 1989. Synthesis and biological activity of an azido derivative of Paclobutrazol, an inhibitor of gibberelin biosynthesis. Plant Physiology. 88, pp. 1425-1429.

Comparative activity of the enantiomers of triadimenol and paclobutrazol as inhibitors of fungal growth and plant sterol and gibberellin biosynthesis

A - Papers appearing in refereed journals

Burden, R. S., Carter, G. A., Clark, T., Cooke, D. T., Croker, S. J., Deas, A. H. B., Hedden, P., James, C. S. and Lenton, J. R. 1987. Comparative activity of the enantiomers of triadimenol and paclobutrazol as inhibitors of fungal growth and plant sterol and gibberellin biosynthesis. Pesticide Science. 21 (4), pp. 253-267. https://doi.org/10.1002/ps.2780210403