Force-induced repolarization of an active crawler

A - Papers appearing in refereed journals

Recho, P., Putelat, T. and Truskinovsky, L. 2019. Force-induced repolarization of an active crawler. New Journal Of Physics. 21, p. 033015. https://doi.org/10.1088/1367-2630/ab05fd

AuthorsRecho, P., Putelat, T. and Truskinovsky, L.
Abstract

We develop a quantitative model of mechanical repolarization in a contraction-driven gel layer mimicking a crawling cell. We show that the force-velocity relations for such active crawlers exhibit multi-valuedness and hysteresis under both force and velocity control. The model predicts steady oscillations of cells attached to an elastic environment and offers a self-consistent mechanical explanation for all experimentally observed outcomes of cell collision tests.

KeywordsCell crawling; Active gel; Active particle; Force-velocity relations; Contact inhibition of locomotion; Cell oscillations
Year of Publication2019
JournalNew Journal Of Physics
Journal citation21, p. 033015
Digital Object Identifier (DOI)https://doi.org/10.1088/1367-2630/ab05fd
Open accessPublished as ‘gold’ (paid) open access
FunderEngineering and Physical Sciences Research Council
Funder project or codeEngineering Nonlinearity
ANR-10-IDEX-0001-02 PSL
Publisher's version
Accepted author manuscript
Output statusPublished
Publication dates
Online19 Mar 2019
Publication process dates
Accepted11 Feb 2019
Copyright licenseCC BY
PublisherIOP Publishing Ltd
ISSN1367-2630

Permalink - https://repository.rothamsted.ac.uk/item/8w957/force-induced-repolarization-of-an-active-crawler

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