Molecular mechanisms of adaptive evolution revealed by global selection for glyphosate resistance [Tansley insight]

A - Papers appearing in refereed journals

Gaines, T. A., Patterson, E. L. and Neve, P. 2019. Molecular mechanisms of adaptive evolution revealed by global selection for glyphosate resistance [Tansley insight]. New Phytologist. 223 (4), pp. 1770-1775.

AuthorsGaines, T. A., Patterson, E. L. and Neve, P.
Abstract

The human‐directed, global selection for glyphosate resistance in weeds has revealed a fascinating diversity of evolved resistance mechanisms, including herbicide sequestration in the vacuole, a rapid cell death response, nucleotide polymorphisms in the herbicide target (5‐enolpyruvylshikimate‐3‐phosphate synthase, EPSPS) and increased gene copy number of EPSPS. For this latter mechanism, two distinct molecular genetic mechanisms have been observed, a tandem duplication mechanism and a large extrachromosomal circular DNA (eccDNA) that is tethered to the chromosomes and passed to gametes at meiosis. These divergent mechanisms have a range of consequences for the spread, fitness, and inheritance of resistance traits, and, particularly in the case of the eccDNA, demonstrate how evolved herbicide resistance can generate new insights into plant adaptation to contemporary environmental stress.

Year of Publication2019
JournalNew Phytologist
Journal citation223 (4), pp. 1770-1775
Digital Object Identifier (DOI)doi:10.1111/nph.15858
Open accessPublished as bronze (free) open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeUnited States: Harnessing next-generation sequencing technologies for eco-evolutionary studies of herbicide resistance and weed biology
Publisher's version
Copyright license
Author copyright
File Access Level
Open
Output statusPublished
Publication dates
Online19 Apr 2019
Publication process dates
Accepted09 Apr 2019
PublisherWiley
ISSN0028-646X

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