The effect of ribonuclease on phage-host interaction

A - Papers appearing in refereed journals

Kleczkowski, A. 1954. The effect of ribonuclease on phage-host interaction. Journal of General Microbiology. 11 (3), pp. 451-458.

AuthorsKleczkowski, A.

SUMMARY: Pancreatic ribonuclease inhibits the multiplication of a Rhizobium bacteriophage in liquid bacterial cultures by preventing permanent combination between phage and host. The addition of ribonuclease after phage has already combined with the bacteria does not prevent phage from multiplying, but it does decrease the rate of multiplication; the enzyme also interferes with multiplication of the bacteria. Experiments with ribonuclease in conjunction with chymotrypsin suggest that phage and bacteria unite in the presence of ribonuclease but that the union is only transitory and ends by the release of still active phage. In the presence of chymotrypsin, however, the phage becomes inactive during this transient union.

Year of Publication1954
JournalJournal of General Microbiology
Journal citation11 (3), pp. 451-458
Digital Object Identifier (DOI)
PubMed ID13221766
Open accessPublished as bronze (free) open access
Publisher's version
Copyright license
Publisher copyright
Output statusPublished
Publication dates
Print01 Dec 1954
PublisherMicrobiology Society

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