Understanding pesticide resistance and developing sustainable crop protection strategies

Project (past)

Project dates01 Apr 2012 to end of 31 Mar 2017
Researchers
Principal InvestigatorLin Field
FunderBiotechnology and Biological Sciences Research Council
Project numberS5193
5193
DepartmentBiological Chemistry and Crop Protection (BCCP)
Research fish codeBBS/E/C/00005193
Grant IDBBS/E/C/00005193

Outputs

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Characterization of the sterol 14alpha-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function

A - Papers appearing in refereed journals
Fan, J., Urban, M., Parker, J. E., Brewer, H. C., Kelly, S. L., Hammond-Kosack, K. E., Fraaije, B. A., Liu, X. and Cools, H. J. 2013. Characterization of the sterol 14alpha-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. New Phytologist. 198 (3), pp. 821-835. https://doi.org/10.1111/nph.12193

Mutation (G275E) of the nicotinic acetylcholine receptor alpha 6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)

A - Papers appearing in refereed journals
Silva, W. M., Berger, M., Bass, C., Williamson, M. S., Moura, D. M. N., Ribeiro, L. M. S. and Siqueira, H. A. A. 2016. Mutation (G275E) of the nicotinic acetylcholine receptor alpha 6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae). Pesticide Biochemistry and Physiology. 131 (July), pp. 1-8. https://doi.org/10.1016/j.pestbp.2016.02.006

Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance

A - Papers appearing in refereed journals
Hawkins, N. J., Cools, H. J., Sierotzki, H., Shaw, M. W., Knogge, W., Kelly, S. L., Kelly, D. E. and Fraaije, B. A. 2014. Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance. Molecular Biology And Evolution. 31 (7), pp. 1793-1802. https://doi.org/10.1093/molbev/msu134

Population genetics of Tuberolachnus salignus, an obligate parthenogenetic aphid

A - Papers appearing in refereed journals
Aradottir, G. I., Hanley, S. J., Collins, C. M., Dawson, K. J., Karp, A., Leather, S. R., Shield, I. F. and Harrington, R. 2012. Population genetics of Tuberolachnus salignus, an obligate parthenogenetic aphid. Agricultural and Forest Entomology. 14 (2), pp. 197-205. https://doi.org/10.1111/j.1461-9563.2011.00559.x

Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance

A - Papers appearing in refereed journals
Hawkins, N. J. and Fraaije, B. A. 2016. Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance. Frontiers in Microbiology. 7, p. 1814. https://doi.org/10.3389/fmicb.2016.01814

Resistance to diamide insecticides in diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae) is associated with a mutation in the membrane-spanning domain of the ryanodine receptor

A - Papers appearing in refereed journals
Troczka, B. J., Zimmer, C. T., Elias, J., Schorn, C., Bass, C. G., Davies, T. G. E., Field, L. M., Williamson, M. S., Slater, R. and Nauen, R. 2012. Resistance to diamide insecticides in diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae) is associated with a mutation in the membrane-spanning domain of the ryanodine receptor. Insect Biochemistry and Molecular Biology. 42, pp. 873-880. https://doi.org/10.1016/j.ibmb.2012.09.001

Sigatoka Disease Complex of Banana in Brazil: Management Practices and Future Directions

A - Papers appearing in refereed journals
Brito Silva Darosci, F., Fraaije, B. A. and Miller, R. N. G. 2015. Sigatoka Disease Complex of Banana in Brazil: Management Practices and Future Directions. Outlooks on Pest Management. 26 (2), pp. 78-81. https://doi.org/10.1564/v26_apr_08

Unseen dangers of inappropriate legislation in agriculture

A - Papers appearing in refereed journals
Field, L. M. 2015. Unseen dangers of inappropriate legislation in agriculture. Food and Energy Security. 4 (1), pp. 1-2. https://doi.org/10.1002/fes3.55

Voltage-gated sodium channels as targets for pyrethroid insecticides

A - Papers appearing in refereed journals
Field, L. M., Davies, T. G. E., O'Reilly, A. O., Williamson, M. S. and Wallace, B. A. 2017. Voltage-gated sodium channels as targets for pyrethroid insecticides. European Biophysics Journal. 46 (7), pp. 675-679. https://doi.org/10.1007/s00249-016-1195-1