Nichola Hawkins

NameNichola Hawkins
Email addressnichola.hawkins@rothamsted.ac.uk
DepartmentBiointeractions and Crop Protection
Research clusterBCP: Pesticide Resistance
ORCIDhttps://orcid.org/0000-0003-3389-0436
Preferred citationHawkins, N. J.
OfficeHarpenden

Research outputs

Digest: Plant-pathogen coevolution extends to shifts in plant breeding systems

Hawkins, N. J. 2019. Digest: Plant-pathogen coevolution extends to shifts in plant breeding systems. Evolution.

Loop-mediated isothermal amplification (LAMP) assays for rapid detection of Pyrenopeziza brassicae (light leaf spot of brassicas)

King, K. M., Krivova, V., Canning, G. G. M., Hawkins, N. J., Kaczmarek, A. M., Perryman, S. A. M., Dyer, P. S., Fraaije, B. A. and West, J. S. 2018. Loop-mediated isothermal amplification (LAMP) assays for rapid detection of Pyrenopeziza brassicae (light leaf spot of brassicas). Plant Pathology. 67 (1), pp. 167-174.

Fitness Penalties in the Evolution of Fungicide Resistance

Hawkins, N. J. and Fraaije, B. A. 2018. Fitness Penalties in the Evolution of Fungicide Resistance. Annual Review of Phytopathology. 56, pp. 339-360.

The evolutionary origins of pesticide resistance

Hawkins, N. J., Bass, C., Dixon, A. and Neve, P. 2018. The evolutionary origins of pesticide resistance. Biological Reviews of the Cambridge Philosophical Society.

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

Fisher, M. C., Hawkins, N. J., Sanglard, D. and Gurr, S. J. 2018. Worldwide emergence of resistance to antifungal drugs challenges human health and food security. Science. 360 (6390), pp. 739-742.

Digest: Plants adapt under attack: genotypic selection and phenotypic plasticity under herbivore pressure

Hawkins, N. J. 2018. Digest: Plants adapt under attack: genotypic selection and phenotypic plasticity under herbivore pressure. Evolution. 72 (5), pp. 1184-1185.

Dose-dependent selection drives lineage replacement during the experimental evolution of SDHI fungicide resistance in Zymoseptoria tritici

Gutierrez-Alonso, O., Hawkins, N. J., Cools, H. J., Shaw, M. W. and Fraaije, B. A. 2017. Dose-dependent selection drives lineage replacement during the experimental evolution of SDHI fungicide resistance in Zymoseptoria tritici. Evolutionary Applications. 10 (10), pp. 1055-1066.

Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14 alpha-demethylase

Sewell, T. R., Hawkins, N. J., Stotz, H. U., Huang, Y. J., Kelly, S. L., Kelly, D. E., Fraaije, B. A. and Fitt, B. D. L. 2017. Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14 alpha-demethylase. Scientific Reports. 7.

British Mycological Society and British Society for Plant Pathology Joint Presidential Meeting 2017 - Fungal Exploitation and Control

Lucas, J. A. and Hawkins, N. J. 2017. British Mycological Society and British Society for Plant Pathology Joint Presidential Meeting 2017 - Fungal Exploitation and Control. Outlooks on Pest Management. 28 (5), pp. 227-229(3).

A conserved fungal glycosyltransferase facilitates pathogenesis of plants by enabling hyphal growth on solid surfaces

King, R., Urban, M., Lauder, R. P., Hawkins, N. J., Evans, M., Plummer, A., Halsey, K., Lovegrove, A., Hammond-Kosack, K. E. and Rudd, J. J. 2017. A conserved fungal glycosyltransferase facilitates pathogenesis of plants by enabling hyphal growth on solid surfaces. PLOS Pathogens. 13 (10), p. e1006672.

Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance

Hawkins, N. J. and Fraaije, B. A. 2016. Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance. Frontiers in Microbiology. 7.

The unique contribution of Rothamsted to ecological research at large temporal scales

Storkey, J., Macdonald, A. J., Bell, J. R., Clark, I. M., Gregory, A. S., Hawkins, N. J., Hirsch, P. R., Todman, L. C. and Whitmore, A. P. 2016. The unique contribution of Rothamsted to ecological research at large temporal scales. in: Dumbrell, A. J., Kordas, R. L. and Woodward, G. (ed.) Advances in Ecological Research 55: Large-Scale Ecology: Model Systems to Global Perspectives Academic Press, Oxford. pp. 3-42

The Rothamsted Long-term Experiments

Macdonald, A. J., Powlson, D. S., Poulton, P. R., Watts, C. W., Clark, I. M., Storkey, J., Hawkins, N. J., Glendining, M. J., Goulding, K. W. T. and McGrath, S. P. 2015. The Rothamsted Long-term Experiments. Valuing Long-term Sites and Experiments for Agriculture and Ecology. Aspects of Applied Biology 128 . Association of Applied Biologists (AAB) Wellesbourne Warwick . pp. 1-10

The evolution of fungicide resistance

Lucas, J. A., Hawkins, N. J. and Fraaije, B. A. 2015. The evolution of fungicide resistance. in: Sariaslani, S. and Gadd, G. M. (ed.) Advances in Applied Microbiology Vol.90 Elsevier. pp. 29-92

Sterol biosynthesis inhibitors: modes of resistance and development of CYP51 mutations

Hawkins, N. J. and Fraaije, B. A. 2014. Sterol biosynthesis inhibitors: modes of resistance and development of CYP51 mutations. 248th National Meeting of the Amercian Chemical Society (ACS) 10-14 August , San Francisco, CA, 2014. American Chemical Society (ACS). pp. 914-AGRO

Evolution and spread of azole-insensitive Zymoseptoria tritici field isolates in the UK

Fraaije, B. A., Atkins, S., Luo, J., Diez De La Fuente, P. and Hawkins, N. J. 2014. Evolution and spread of azole-insensitive Zymoseptoria tritici field isolates in the UK. American Phytopathological Society (APS). pp. S3.41

The role of multiple CYP51 paralogues in intrinsic and acquired azole sensitivity differences

Hawkins, N. J., Cools, H. J. and Fan, J. 2014. The role of multiple CYP51 paralogues in intrinsic and acquired azole sensitivity differences. in: Fraaije, B. A., Deising, H. B. and Dehne, H. W. (ed.) Modern fungicides and antifungal compounds. Vol. 7 Deutsche Phytomedizinische Gesellschaft, Braunschweig. pp. 97-102

Sterol biosynthesis inhibitors: modes of resistance and development of CPY51 mutations

Hawkins, N. J. and Fraaije, B. A. 2014. Sterol biosynthesis inhibitors: modes of resistance and development of CPY51 mutations. Abstracts 13th IUPAC International Congress of Pesticide Chemistry, San Francisco, 10-14 August 2014 . pp. 234

Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance

Hawkins, N. J., Cools, H. J., Sierotzki, H., Shaw, M. W., Knogge, W., Kelly, S. L., Kelly, D. E. and Fraaije, B. A. 2014. Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance. Molecular Biology And Evolution. 31 (7), pp. 1793-1802.

CPY51 paralogues and azole sensitivity in Rhynchosporium commune

Hawkins, N. J., Cools, H. J. and Fraaije, B. A. 2013. CPY51 paralogues and azole sensitivity in Rhynchosporium commune. Abstracts 14th Congress of the European Society for Evolutionary Biology, Lisbon, 19-24 August 2013 . pp. 859

Mapping the adaptive landscape of Mycosphaerella graminicola CYP51 under selection by azole fungicides

Hawkins, N. J., Cools, H. J. and Fraaije, B. A. 2013. Mapping the adaptive landscape of Mycosphaerella graminicola CYP51 under selection by azole fungicides. Abstracts 14th Congress of the European Society for Evolutionary Biology, Lisbon, 19-24 August 2013 . pp. 19

Constraints on the evolution of azole resistance in plant pathogenic fungi

Cools, H. J., Hawkins, N. J. and Fraaije, B. A. 2013. Constraints on the evolution of azole resistance in plant pathogenic fungi. Plant Pathology. 62 (Suppl. 1), pp. 36-42.

CYP51 paralogues and azole sensitivity in Rhynchosporium commune

Hawkins, N. J., Cools, H. J. and Fraaije, B. A. 2013. CYP51 paralogues and azole sensitivity in Rhynchosporium commune. Chinese Society for Plant Pathology. pp. 143-144

Evolution and spread of Mycosphaerella graminicola isolates overexpressing CYP51 or carrying different CYP51 variants in response to azole fungicide applications

Fraaije, B. A., Atkins, S., Luo, J., De La Fuente, P. D., Hawkins, N. J. and Cools, H. J. 2013. Evolution and spread of Mycosphaerella graminicola isolates overexpressing CYP51 or carrying different CYP51 variants in response to azole fungicide applications. Chinese Society for Plant Pathology. pp. 144

Recent evolution of Rhynchosporium secalis populations in response to selection by triazoles. PhD thesis, University of Reading

Hawkins, N. J. 2012. Recent evolution of Rhynchosporium secalis populations in response to selection by triazoles. PhD thesis, University of Reading. F - Theses

Molecular mechanisms of altered triazole sensitivity in Rhynchosporium secalis

Hawkins, N. J., Cools, H. J., Shaw, M. W., Sierotzki, H. and Fraaije, B. A. 2011. Molecular mechanisms of altered triazole sensitivity in Rhynchosporium secalis. Dehne, H. W. (ed.) Modern fungicides and antifungal compounds VI . DPG, Braunschwieg. pp. 129-134

CYP51 paralogues and azole fungicide sensitivity in Rhynchosporium secalis

Hawkins, N. J., Cools, H. J., Sierotzki, H., Shaw, M. and Fraaije, B. A. 2010. CYP51 paralogues and azole fungicide sensitivity in Rhynchosporium secalis. Abstracts 10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology, Woods Hole, 3-7 October 2010 .