Ahmed Tawfike

NameAhmed Tawfike
Job titleScientific Specialist - Metabolomics Data Analyst
Email addressahmed.tawfike@rothamsted.ac.uk
DepartmentComputational and Analytical Sciences
Research clusterCAS: Molecular Discovery
OfficeHarpenden

Research outputs

Cytotoxic Activity and Metabolic Profiling of Fifteen Euphorbia Species

El-Hawary, S. S., Mohammed, R., Tawfike, A. F., Lithy, N. M., AbouZid, S. F., Amin, M. N., Abdelmohsen, U. R. and Amin, E. 2021. Cytotoxic Activity and Metabolic Profiling of Fifteen Euphorbia Species. Metabolites. 11 (1), p. 15. https://doi.org/10.3390/metabo11010015

Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides

Eskandari, H., Ghanadian, M., Noleto-Dias, C., Lomax, C., Tawfike, A., Christiansen, G., Sutherland, D. S., Ward, J. L., Mohammad-Beigi, H. and Otzen, D. E. 2020. Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides. ACS Chemical Neuroscience. 11 (19), pp. 3161-3173. https://doi.org/10.1021/acschemneuro.0c00528

Transitions in wheat endosperm metabolism upon transcriptional induction of oil accumulation by oat endosperm WRINKLED1

Grimberg, A., Wilkinson, M. D., Snell, P., De Vos, R. P., Gonzalez-Thuillier, I., Tawfike, A., Ward, J. L., Carlsson, A. S., Shewry, P. R. and Hofvander, P. 2020. Transitions in wheat endosperm metabolism upon transcriptional induction of oil accumulation by oat endosperm WRINKLED1 . BMC Plant Biology. 20, p. 235. https://doi.org/10.1186/s12870-020-02438-9

Metabolomics analysis and biological investigation of three Malvaceae plants

Abdelhafez, O. H., Othman, E. M., Fahim, J. R., Desoukey, S. Y., Pimentel-Elardo, S. M., Nodwell, J. R., Schirmeister, T., Tawfike, A. and Adbelmohsen, U. R. 2019. Metabolomics analysis and biological investigation of three Malvaceae plants. Phytochemical Analysis. https://doi.org/10.1002/pca.2883

Influence of Pickling Process on Allium cepa and Citrus limon Metabolome as Determined via Mass Spectrometry-Based Metabolomics

Tawfike, A. F., Farag, M. A., Donia, M. S., Ehrlich, A. and Wessjohann, L. A. 2019. Influence of Pickling Process on Allium cepa and Citrus limon Metabolome as Determined via Mass Spectrometry-Based Metabolomics. Molecules. 24 (5), p. 928. https://doi.org/10.3390/molecules24050928

Application of metabolomics and molecular networking in investigating the chemical profile and antitrypanosomal activity of British bluebells ( Hyacinthoides non-scripta )

Raheem, D., Tawfike, A. F, Abdulmohsen, U., Edrada-Ebel, R. and Fitzsimmons-Thoss, V. 2019. Application of metabolomics and molecular networking in investigating the chemical profile and antitrypanosomal activity of British bluebells ( Hyacinthoides non-scripta ). Scientific Reports. 9 (1), p. 2547. https://doi.org/10.1038/s41598-019-38940-w

New bioactive metabolites from the elicited marine sponge-derived bacterium Actinokineospora spheciospongiae sp. nov.

Tawfike, A., Attia, E. Z., Desoukey, S. Y., Hajjar, D., Makki, A. A., Schupp, P. J., Edrada-Ebel, R. and Abdelmohsen, U. R. 2019. New bioactive metabolites from the elicited marine sponge-derived bacterium Actinokineospora spheciospongiae sp. nov. AMB Express. 9 (12). https://doi.org/10.1186/s13568-018-0730-0

Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

Mohammed-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A., Shafer, N.P., Amiri-Nowdijeh, A., Eskandari, E., Moller, I.M., Hosseini-Mazinani, M., Christiansen, G., Ward, J. L., Morshedi, D. and Otzen, D.E 2019. Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. Journal of Biological Chemistry. 294, pp. 4215-4232. https://doi.org/10.1074/jbc.RA118.005723

Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics

Tawfike, A. F, Romli, M., Clements, C., Abbott, G., Young, L., Schumacher, M., Diederich, M., Farag, M. and Edrada-Ebel, R. 2019. Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics. Journal Of Chromatography B. 1106-1107 (1 February), pp. 71-83. https://doi.org/10.1016/j.jchromb.2018.12.032

Effects of Organic and Conventional Crop Nutrition on Profiles of Polar Metabolites in Grain of Wheat

Shewry, P. R., Rakszegi, M., Lovegrove, A., Amos, D., Corol, D. I., Tawfike, A., Miko, P. and Ward, J. L. 2018. Effects of Organic and Conventional Crop Nutrition on Profiles of Polar Metabolites in Grain of Wheat. Journal of Agricultural and Food Chemistry - JAFC. 66 (21), pp. 5346-5351. https://doi.org/10.1021/acs.jafc.8b01593

Metabolomic-Guided Isolation of Bioactive Natural Products from Curvularia sp., an Endophytic Fungus of Terminalia laxiflora

Tawfike, A. F., Abbott, G., Young, L. and Edrada-Ebel, R. 2018. Metabolomic-Guided Isolation of Bioactive Natural Products from Curvularia sp., an Endophytic Fungus of Terminalia laxiflora. Planta Medica. 84 (3), pp. 182-190. https://doi.org/10.1055/s-0043-118807

Metabolomic Tools to Assess the Chemistry and Bioactivity of Endophytic Aspergillus Strain

Tawfike, A. F., Tate, R., Abbott, G., Young, L., Viegelmann, C., Schumacher, M., Diederich, M. and Edrada-Ebel, R. 2017. Metabolomic Tools to Assess the Chemistry and Bioactivity of Endophytic Aspergillus Strain. Chemistry & Biodiversity. 14, p. e1700040. https://doi.org/10.1002/cbdv.201700040

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