Items where Author is "Fraaije, Bart"

Number of items: 173.
  • Learning from fungicide resistance: Evolutionary insights to guide RNAi-based control of fungal crop pathogens. (2025) Alkemade, J. A., Hawkins, Nichola, Baraldi, E., Buddie, A. G., Cockerton, H. M., Corkley, Isabel, Fraaije, Bart, Gaya, E., Gifford, D. R., Hartig, F., Kanyuka, Kostya, Koch, A., Sanchez, J. N., Preston, G. M., Seidl, M. F., Spanu, P. D., Werner, B. T., Lyu, J., Barraclough, Tim
  • Evolution of decreased sensitivity to azole fungicides in western European populations of Plenodomus lingam (cause of Phoma leaf spot / stem canker on oilseed rape). (2024) King, Kevin, Barr, Leo, Bousquet, L., Glaab, A., Canning, Gail, Ritchie, F., Kildea, S., Fraaije, Bart, West, Jon
  • Choice of resistance management tactics: how flexible should we be? (2024) Paveley, N., Young, C., Fraaije, Bart, Vandenbosch, Frank, Kildea, S., Burnett, F., Havis, N., Lees, A., Lynott, J., Bain, R., Corkley, Isabel, Ritchie, F.
  • Modelling resistance management benefits of diversity within a fungicidal mode of action with incomplete cross-resistance: the azoles example. (2024) Corkley, Isabel, Vandenbosch, Frank, Fraaije, Bart, Shaw, M.W, Helps, Joe, Mikaberidze, A., Milne, Alice, Paveley, N.D. picture_as_pdf
  • Aerobiology of the Wheat Blast Pathogen: Inoculum Monitoring and Detection of Fungicide Resistance Alleles. (2023) Vicentini, S. N. C., Hawkins, Nichola, King, Kevin, Moreira, S. I., Custodio, A. A. D. P., Junior, R. P. L., Portalanza, D., Garces-Fiallos, F. R., Krug, L. D., West, Jon, Fraaije, Bart, Junior, W. C. D. J., Ceresini, P. C.
  • Epidemiological studies of pan-azole resistant Aspergillus fumigatus populations sampled during tulip cultivation show clonal expansion with acquisition of multi-fungicide resistance as potential driver. (2021) Fraaije, Bart, Atkins, Sarah, Santos, R. F., Hanley, Steve, West, Jon, Lucas, John
  • Lack of an Intron in Cytochrome b and Overexpression of Sterol 14 alpha-Demethylase Indicate a Potential Risk for QoI and DMI Resistance Development in Neophysopella spp. on Grapes. (2021) Santos, R. F., Amorium, L., Machado Wood, Ana, Bibiano, L. B. J., Fraaije, Bart
  • Monitoring of Brazilian wheat blast field populations reveals resistance to QoI, DMI, and SDHI fungicides. (2021) Vicentini, S. N. C., Casado, P. S., DeCarvalho, G., Moreira, S. I., Dorgian, A. F., Silva, T. C., Silva, A. G., Custodio, A. P. A., Gomes, A. C. S., Maciel, J. L. N., Hawkins, Nichola, McDonald, B. A., Fraaije, Bart, Ceresini, P. C. picture_as_pdf
  • Fungicide resistance management: maximising the effective life of plant protection products. (2021) Corkley, Isabel, Fraaije, Bart, Hawkins, Nichola picture_as_pdf
  • Fungicide resistance status and chemical control options for the brassica pathogen Pyrenopeziza brassicae. (2021) King, Kevin, Bucur, D. E., Hawkins, Nichola, Kaczmarek, A. M., Duan, Y., Kildea, S., West, Jon, Fraaije, Bart picture_as_pdf
  • Remarkable recent changes in genetic diversity of the avirulence gene AvrStb6 in global populations of the wheat pathogen Zymoseptoria tritici. (2021) Stephens, Chris, Olmez, F., Blyth, Hannah, McDonald, M., Bansal, Anu, Turgay, E. B., Hahn, Florian, Saintenac, C., Nekrasov, Vladimir, Solomon, P., Milgate, A., Fraaije, Bart, Rudd, Jason, Kanyuka, Kostya
  • Contrasting levels of genetic predictability in the evolution of resistance to major classes of fungicides. (2021) Hawkins, Nichola, Fraaije, Bart
  • The Multi-Fungicide Resistance Status of Aspergillus fumigatus Populations in Arable Soils and the Wider European Environment. (2020) Fraaije, Bart, Atkins, Sarah, Hanley, Steve, Macdonald, Andy, Lucas, John
  • The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda. (2020) Verweij, P. E., Lucas, John, Arendrup, M. C., Bowyer, P., Brinkmann, A. J. F., Denning, D. W., Dyer, P. S., Fisher, M. C., Geenen, P. L., Gisi, U., Hermann, D., Hoogendijk, A., Kiers, E., Lagrou, K., Melchers, W. J. G., Rhodes, J., Rietveld, A. G., Schoustra, S. E., Stenzel, K., Zwaan, B. J., Fraaije, Bart
  • Widespread distribution of resistance to triazole fungicides in Brazilian populations of the wheat blast pathogen. (2020) Poloni, N. M., Carvalho, G., Vicentini, S. N. C., Dorigan, A. F., Maciel, J. L. N., McDonald, B. A., Moreira, S. I., Hawkins, Nichola, Fraaije, Bart, Kelly, D. E., Kelly, S. L., Ceresini, P. C. picture_as_pdf
  • Novel Multiplex and Loop-Mediated Isothermal Amplification (LAMP) Assays for Rapid Species and Mating-Type Identification of Oculimacula acuformis and O. yallundae (Causal Agents of Cereal Eyespot), and Application for Detection of Ascospore Dispersal and in planta Use. (2020) King, Kevin, Eyres, G. J., West, Jon, Siraf, Clara, Matusinsky, P., Palicova, J., Canning, Gail, Bateman, Geoff, Fraaije, Bart, Dyer, P. S.
  • A phylogenetically distinct lineage of Pyrenopeziza brassicae associated with chlorotic leaf spot of Brassicaceae in North America. (2019) Carmody, S., King, Kevin, Ocamb, C., Fraaije, Bart, West, Jon, Du Toit, L.
  • First application of loop-mediated isothermal amplification (LAMP) assays for rapid identification of mating type in the heterothallic fungus Aspergillus fumigatus. (2019) King, Kevin, Hawkins, Nichola, Atkins, Sarah, Dyer, P. S., West, Jon, Fraaije, Bart
  • Dramatic recent changes in the population genetic diversity of avirulence gene AvrStb6 in the pathogenic fungus Zymoseptoria tritici. (2019) Stephens, Chris, Blyth, Hannah, Olmez, F., Turgay, E. B., Chen, Hongxin, McDonald, M., Solomon, P., Milgate, A., Fraaije, Bart, Rudd, Jason, Kanyuka, Kostya
  • Impact of epoxiconazole on Fusarium head blight control, grain yield and deoxynivalenol accumulation in wheat. (2018) Duan, Yabing, Xiao, X., Li, T., Chen, W., Wang, J., Fraaije, Bart, Zhou, M. G. picture_as_pdf
  • Simultaneous detection of multiple benzimidazole resistant β-tubulin variants of Botrytis cinerea using loop mediated isothermal amplification. (2018) Duan, Yabing, Yang, Yi, Wang, J. X., Chen, C. J., Steinberg, G., Fraaije, Bart, Zhou, M. G.
  • Fitness Penalties in the Evolution of Fungicide Resistance. (2018) Hawkins, Nichola, Fraaije, Bart picture_as_pdf
  • Arable Crop Disease Alert System - AHDB Project Report 594. (2018) West, Jon, Canning, Gail, King, Kevin, Fraaije, Bart, Wili, S.
  • Development and application of a simple, rapid and sensitive method for detecting moderately carbendazim‐resistant isolates in Botrytis cinerea. (2018) Duan, Yabing, Yang, Y., Li, M. X., Fraaije, Bart, Zhou, M. G.
  • Dramatic changes in genetic diversity of the avirulence effector AvrStb6 in global populations of the wheat pathogen Zymoseptoria tritici. (2018) Stephens, Chris, Blyth, Hannah, Olmez, F., McDonald, M., Solomon, P., Milgate, A., Chen, Hongxin, Fraaije, Bart, Rudd, Jason, Kanyuka, Kostya desktop_windows
  • Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14 alpha-demethylase. (2017) Sewell, T. R., Hawkins, Nichola, Stotz, H. U., Huang, Y. J., Kelly, S. L., Kelly, D. E., Fraaije, Bart, Fitt, Bruce
  • Non‐target site SDHI resistance is present as standing genetic variation in field populations of Zymoseptoria tritici. (2017) Yamashita, M., Fraaije, Bart
  • Changes in field dose–response curves for demethylation inhibitor (DMI) and quinone outside inhibitor (QoI) fungicides against Zymoseptoria tritici, related to laboratory sensitivity phenotyping and genotyping assays. (2017) Blake, J. J., Gosling, P., Fraaije, Bart, Burnett, F. J., Knight, S. M., Kildea, S., Paveley, N. D. picture_as_pdf
  • Dose-dependent selection drives lineage replacement during the experimental evolution of SDHI fungicide resistance in Zymoseptoria tritici. (2017) Gutierrez-Alonso, O., Hawkins, Nichola, Cools, H. J., Shaw, M. W., Fraaije, Bart
  • Loop-mediated isothermal amplification (LAMP) assays for rapid detection of Pyrenopeziza brassicae (light leaf spot of brassicas). (2017) King, Kevin, Krivova, V., Canning, G. G. M., Hawkins, Nichola, Kaczmarek, A. M., Perryman, Sarah, Dyer, P. S., Fraaije, Bart, West, Jon picture_as_pdf
  • Strategies to delay the development of fungicide resistance : Alternation , mixtures or restricting the number of treatments? (2017) Young, C., Vandenbosch, Frank, Fraaije, Bart, Burnett, F., Knight, S., Gosling, P., Paveley, N.
  • Genetic analysis of Pyrenopeziza brassicae, cause of light leaf spot of brassicas, in the European Union, Oceania, and North America. (2017) Carmody, S., King, Kevin, Classen, B., Fraaije, Bart, West, Jon, Ocamb, C. M., du Toit, L.
  • Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance. (2016) Hawkins, Nichola, Fraaije, Bart
  • Wheat seed embryo excision enables the creation of axenic seedlings and Koch's postulates testing of putative bacterial endophytes. (2016) Robinson, R. J., Fraaije, Bart, Clark, Ian, Jackson, R. W., Hirsch, Penny, Mauchline, Tim
  • Effector biology of Zymoseptoria tritici during interactions with wheat and with non-host plants. (2016) Kettles, Graeme, King, Robert, Hooper, J., Skinner, W., Hargreaves, J., Kanyuka, Kostya, Fraaije, Bart, Rudd, Jason
  • Endophytic bacterial community composition in wheat (Triticum aestivum) is determined by plant tissue type, developmental stage and soil nutrient availability. (2016) Robinson, R. J., Fraaije, Bart, Clark, Ian, Jackson, R. W., Hirsch, Penny, Mauchline, Tim picture_as_pdf
  • Proposal for a unified nomenclature for target-site mutations associated with resistance to fungicides. (2016) Mair, W., Lopez-Ruiz, F., Stammler, G ., Clark, W., Burnett, F., Hollomon, D., Ishii, H., Thind, T. S., Brown, J. K., Fraaije, Bart, Cools, H. J., Shaw, M., Fillinger, S., Walker, A. S., Mellado, E., Schnabel, G., Mehl, A., Oliver, R. P.
  • Resistance management: we know why but so we know how? (2016) Lucas, J. A.
  • Sigatoka Disease Complex of Banana in Brazil: Management Practices and Future Directions. (2015) Brito Silva Darosci, F., Fraaije, Bart, Miller, R. N. G. picture_as_pdf
  • Airborne sampling and optical sensing methods for macro scale mapping. (2015) West, Jon, Canning, Gail, Heard, S., Fraaije, Bart, Bonants, P., Van Gent-Pelzer, M., Nicolaisen, M., Justesen, A. F., Wili, S. G.
  • Evidence-based resistance management: a review of existing evidence. (2015) Vandenbosch, Frank, Paveley, N., Fraaije, Bart, Van Den Berg, F., Oliver, R.
  • The evolution of fungicide resistance. (2015) Lucas, J. A., Hawkins, Nichola, Fraaije, Bart picture_as_pdf
  • The use of mathematical models to guide fungicide resistance management decisions. (2015) Vandenbosch, Frank, Fraaije, Bart, Oliver, R., Van Den Berg, F., Paveley, N.
  • Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance. (2014) Hawkins, Nichola, Cools, H. J., Sierotzki, H., Shaw, M. W., Knogge, W., Kelly, S. L., Kelly, D. E., Fraaije, Bart
  • Alterations in the predicted regulatory and coding regions of the sterol 14alpha-demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen Pyrenopeziza brassicae. (2014) Carter, H. E., Fraaije, Bart, West, Jon, Kelly, S. L., Mehl, A., Shaw, M. W., Cools, H. J.
  • Evolution and spread of azole-insensitive Zymoseptoria tritici field isolates in the UK. (2014) Fraaije, Bart, Atkins, S., Luo, Jing, Diez De La Fuente, P., Hawkins, Nichola description
  • Sterol biosynthesis inhibitors: modes of resistance and development of CPY51 mutations. (2014) Hawkins, Nichola, Fraaije, Bart
  • Sterol biosynthesis inhibitors: modes of resistance and development of CYP51 mutations. (2014) Hawkins, Nichola, Fraaije, Bart
  • Sustainable crop protection: the storm before the calm? (2014) Lucas, J. A., Fraaije, Bart
  • Use of loop-mediated isothermal amplification assays to detect azole-insensitive CYP51- overexpressing strains of Zymoseptoria tritici. (2014) Fraaije, Bart description
  • The impact of tissue type, growth stage and fertilizers on the community structure of cultured bacterial wheat endophytes in the Broadbalk experiment. (2014) Robinson, R. R., Fraaije, Bart, Clark, Ian, Jackson, R. W., Hirsch, Penny, Mauchline, Tim
  • The role of multiple CYP51 paralogues in intrinsic and acquired azole sensitivity differences. (2014) Hawkins, Nichola, Cools, H. J., Fan, J.
  • Characterization of the sterol 14alpha-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. (2013) Fan, J., Urban, Martin, Parker, J. E., Brewer, H. C., Kelly, S. L., Hammond-Kosack, Kim, Fraaije, Bart, Liu, X., Cools, H. J.
  • Bacterial endophytes in wheat (Triticum aestivum): isolation, characterisation and bio-prospecting. (2013) Robinson, R., Mauchline, Tim, Hirsch, Penny, Jackson, R., Frost, H., Fraaije, Bart
  • CPY51 paralogues and azole sensitivity in Rhynchosporium commune. (2013) Hawkins, Nichola, Cools, H. J., Fraaije, Bart
  • CYP51 paralogues and azole sensitivity in Rhynchosporium commune. (2013) Hawkins, Nichola, Cools, H. J., Fraaije, Bart
  • Constraints on the evolution of azole resistance in plant pathogenic fungi. (2013) Cools, H. J., Hawkins, Nichola, Fraaije, Bart
  • Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates. (2013) Carter, H. E., Cools, H. J., West, Jon, Shaw, M. W., Fraaije, Bart picture_as_pdf
  • Detection of azole insensitive CYP51 over-expressing strains of Mycosphaerella graminicola using loop-mediated isothermal amplification (LAMP) assays. (2013) Fraaije, Bart, Cools, H. J.
  • Evolution and spread of Mycosphaerella graminicola isolates overexpressing CYP51 or carrying different CYP51 variants in response to azole fungicide applications. (2013) Fraaije, Bart, Atkins, S., Luo, Jing, De La Fuente, P. D., Hawkins, Nichola, Cools, H. J.
  • Genus-specific CYP51C of Fusarium graminearum identified as a novel CYP51 rather than azole fungicide target sterol 14alpha-demethylases. (2013) Fan, J., Urban, Martin, Parker, J. E., Brewer, H. C., Kelly, S. L., Hammond-Kosack, Kim, Fraaije, Bart, Liu, X., Cools, H. J.
  • Mapping the adaptive landscape of Mycosphaerella graminicola CYP51 under selection by azole fungicides. (2013) Hawkins, Nichola, Cools, H. J., Fraaije, Bart
  • New developments in identification and quantification of airborne inoculum. (2013) West, Jon, Heard, S., Canning, Gail, Fraaije, Bart, Hammond-Kosack, Kim
  • One step ahead? The evolution of fungicide resistance in Septoria leaf blotch of wheat. (2013) Lucas, J. A., Cools, H. J., Fraaije, Bart
  • Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-alpha-demethylase. (2013) Parker, J. E., Warrilow, A. G. S., Cools, H. J., Fraaije, Bart, Lucas, J. A., Rigdova, K., Griffiths, W. J., Kelly, D. E., Kelly, S. L. picture_as_pdf
  • Risk assessment on the impact of environmental usage of triazoles on the development and spread of resistance to medical triazoles in Aspergillus species (ECDC Technical Report). (2013) Kleinkauf, N., Verweij, P. E., Arendrup, M. C., Donnelly, P. J., Cuenca-Estrella, M., Fraaije, Bart, Melchers, W. J. G., Adriaenssens, N., Kema, G. H. J., Ullmann, A., Bowyer, P., Denning, D. W.
  • Simultaneous real-time PCR detection of Fusarium asiaticum, F. ussurianum and F. vorosii, representing the Asian clade of the F. graminearum species complex. (2013) Fernandez-Ortuno, D., Waalwijk, C., Van Der Lee, T., Fan, J., Atkins, S., West, Jon, Fraaije, Bart picture_as_pdf
  • Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control. (2013) Cools, H. J., Fraaije, Bart picture_as_pdf
  • Update on the evolution and selection for azole and Succinate DeHydrogenase Inhibitor (SDHI) fungicide insensitivity in UK Mycosphaerella graminicola populations. (2013) Fraaije, Bart
  • Overexpression of the sterol 14α-demethylase gene (MgCYP51) in Mycosphaerella graminicola isolates confers a novel azole fungicide sensitivity phenotype. (2012) Cools, H. J., Bayon, Carlos, Atkins, S., Lucas, J. A., Fraaije, Bart picture_as_pdf
  • Detection and quantification of airborne inoculum of Pyrenopeziza brassicae in Polish and UK winter oilseed rape crops by real-time PCR assays. (2012) Karolewski, Z., Kaczmarek, J., Jedryczka, M., Cools, H. J., Fraaije, Bart, Lucas, J. A., Latunde-Dada, A. O. picture_as_pdf
  • Genetic basis of control of Rynchosporium secalis infection and symptom expression in barley. (2012) Looseley, M. E., Newton, A. C., Atkins, S. D., Fitt, Bruce, Fraaije, Bart, Thomas, W. T. B., Keith, R., Macaulay, M., Lynott, J., Harrap, D. picture_as_pdf
  • Investigations into the molecular mechanisms responsible for the decline in sensitivity to DMI fungicides in Mycosphaerella graminicola populations. (2012) Fraaije, Bart, Cools, H. J.
  • Reduced azole sensitivity in the oilseed rape pathogen Pyrenopziza brassicae. (2012) Carter, H. E., Cools, H. J., West, Jon, Shaw, M., Mehl, A., Fraaije, Bart
  • Resistance to azole fungicides in Mycosphaerella graminicola: mechanisms and management. (2012) Cools, H. J., Fraaije, Bart
  • Risk assessment studies on succinate dehydrogenase inhibitors, the new weapons in the battle to control Septoria leaf blotch in wheat. (2012) Fraaije, Bart, Bayon, Carlos, Atkins, S., Cools, H. J., Lucas, J. A., Fraaije, M. W.
  • Role of inoculum sources in Rhynchosporium population dynamics and epidemics on barley. (2012) Fitt, Bruce, Atkins, S. D., Fraaije, Bart, Lucas, J. A., Newton, A. C., Looseley, M., Werner, P., Harrap, D., Ashworth, M., Southgate, J., Phillips, H., Gilchrist, A.
  • Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola. (2011) Mullins, J. G. L., Parker, J. E., Cools, H. J., Togawa, R. C., Lucas, J. A., Fraaije, Bart, Kelly, D. E., Kelly, S. L.
  • The CYP51C gene, a novel and useful phylogenetic marker to distinguish different Fusarium species on cereals. (2011) Fernandez-Ortuno, D., Loza-Reyes, E., Rogers, S. L., Fraaije, Bart
  • Derivation and testing of a model to predict selection for fungicide resistance. (2011) Hobbelen, P. H. F., Paveley, N. D., Fraaije, Bart, Lucas, J. A., Vandenbosch, Frank
  • Development of QoI resistance in Ramularia collo-cygni populations. (2011) Fountaine, J. M., Burnett, F. J., Fraaije, Bart
  • Functional characterisation of Mycosphaerella graminicola sterol 14alpha-demethylase variants resistant to azole fungicides. (2011) Cools, H. J., Parker, J. E., Kelly, D. E., Lucas, J. A., Kelly, S. L., Fraaije, Bart
  • Impact of recently emerged sterol 14alpha-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity. (2011) Cools, H. J., Mullins, J. G. L., Fraaije, Bart, Parker, J. E., Kelly, D. E., Lucas, J. A., Kelly, S. L. picture_as_pdf
  • Impacts of changing air composition on severity of arable crop disease epidemics. (2011) Fitt, Bruce, Fraaije, Bart, Chandramohan, P., Shaw, M. W.
  • Mechanism of binding of prothioconazole to Mycosphaerella graminicola CYP51 differs from that of other azole antifungals. (2011) Parker, J. E., Warrilow, A. G. S., Cools, H. J., Martel, C. M., Nes, W. D., Fraaije, Bart, Lucas, J. A., Kelly, D. E., Kelly, S. L. picture_as_pdf
  • Molecular mechanisms of altered triazole sensitivity in Rhynchosporium secalis. (2011) Hawkins, Nichola, Cools, H. J., Shaw, M. W., Sierotzki, H., Fraaije, Bart
  • The use of a CYP51C gene based on PCR-RFLP assay for simultaneous detection and identification of Fusarium avenaceum and F. tricinctum in wheat. (2011) Fernandez-Ortuno, D., Atkins, Sarah, Fraaije, Bart picture_as_pdf
  • CYP51 paralogues and azole fungicide sensitivity in Rhynchosporium secalis. (2010) Hawkins, Nichola, Cools, H. J., Sierotzki, H., Shaw, M., Fraaije, Bart
  • The CYP51C gene, a novel and useful phylogenetic marker to distinguish different Fusarium species on cereals. (2010) Fernandez-Ortuno, D., Loza-Reyes, E., Rogers, S. L., Fraaije, Bart
  • The CYP51C gene, a novel marker for phylogenetic analysis of Fusarium species. (2010) Fernandez-Ortuno, D., Loza-Reyes, E., Rogers, S. L., Fraaije, Bart
  • The CYP51C gene, a reliable marker to resolve interspecific phylogenetic relationships within the Fusarium species complex and a novel target for species-specific PCR. (2010) Fernandez-Ortuno, D., Loza-Reyes, E., Atkins, Sarah, Fraaije, Bart picture_as_pdf
  • Derivation and validation of a model to predict selection for fungicide resistance. (2010) Hobbelen, P. H., Paveley, N. D., Fraaije, Bart, Lucas, J. A., Vandenbosch, Frank
  • Development of QO1 resistance in Ramularia collocygni populations. (2010) Fountaine, J. M., Burnett, F. J., Fraaije, Bart
  • Effects of DMI fungicides on selection of CYP51 variants in UK populations of Mycosphaerella graminicola. (2010) Fraaije, Bart, Rogers, S., Bayon, Carlos, Cools, H. J., Lucas, J. A.
  • Evolutionary bi-stability in pathogen transmission mode. (2010) Vandenbosch, Frank, Fraaije, Bart, Van Den Berg, F., Shaw, M. W. picture_as_pdf
  • Functional characterisation of Mycosphaerella graminicola sterol 14alpha-demethylase (MgCYP51) variants resistant to azole fungicides. (2010) Cools, H. J., Parker, J. E., Motteram, J., Kelly, D. E., Lucas, J. A., Rudd, Jason, Kelly, S. L., Fraaije, Bart
  • Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function. (2010) Cools, H. J., Parker, J. E., Kelly, D. E., Lucas, J. A., Fraaije, Bart, Kelly, S. L. picture_as_pdf
  • Identification and characterisation of Mycosphaerella graminicola secreted or surface-associated proteins with variable intragenic coding repeats. (2010) Rudd, Jason, Antoniw, John, Marshall, R., Motteram, J., Fraaije, Bart, Hammond-Kosack, Kim picture_as_pdf
  • Investigating altered triazole sensitivity in Rhynchosporium secalis. (2010) Hawkins, N. D., Cools, H. J., Shaw, M. W., Sierotzki, H., Fraaije, Bart
  • Molecular mechanisms of altered fungicide sensitivity in Rhynchosporium secalis. (2010) Hawkins, N. D., Cools, H. J., Shaw, M. W., Sierotzki, H., Fraaije, Bart
  • Prothioconazole binds to Mycosphaerella graminicola CYP51 by a different mechanism compared to other azole antifungals. (2010) Parker, J. E., Warrilow, A., Cools, H. J., Martel, C. M., Nes, W. D., Fraaije, Bart, Lucas, J. A., Kelly, D. E., Kelly, S. L.
  • Rynchosporium secalis: a historical perspective. (2010) Atkins, S. D., King, Kevin, Fraaije, Bart, Newton, A. C.
  • Succinate dehydrogenase inhibitor resistance risk assessment studies on Mycosphaerella graminicola the causal agent of septoria leaf blotch. (2010) Bayon, Carlos, Fraaije, M. W., Cools, H. J., Rogers, S. L., Lucas, J. A., Fraaije, Bart
  • The epidemiological importance of asymptomatic infection of winter barley by Rhynchosporium secalis and its consequences for crop protection and breeding. (2010) Atkins, S. D., Fitt, Bruce, Fraaije, Bart, Harvey, Steve, Lynott, J., Newton, A. C.
  • The role of seeds and airborne inoculum in the initiation of leaf blotch (Rhynchosporium secalis) epidemics in winter barley. (2010) Fountaine, J. M., Shaw, M. W., Ward, E., Fraaije, Bart
  • Impact of proquinazid on appressorial development of the barley powdery mildew fungus Blumeria graminis f.sp hordei. (2009) Gilbert, S. R., Cools, H. J., Fraaije, Bart, Bailey, A. M., Lucas, J. A. picture_as_pdf
  • Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides. (2009) Bean, T. P., Cools, H. J., Lucas, J. A., Hawkins, N. D., Ward, Jane, Shaw, M. W., Fraaije, Bart
  • Are azole fungicides losing ground against Septoria wheat disease? Resistance mechanisms in Mycosphaerella graminicola. (2008) Cools, H. J., Fraaije, Bart picture_as_pdf
  • Adaptation of Mycosphaerella graminicola populations to azole fungicides in the UK. (2008) Fraaije, Bart, Cools, H. J., Motteram, J., Gilbert, S. R., Kim, S-H., Lucas, J. A.
  • Asymptomatic infection of winter and spring barley by Rhynchosporium secalis: effects and implications for epidemiology and host resistance. (2008) Atkins, S. D., Stonard, J. F., Fraaije, Bart, Lucas, J. A., Fitt, Bruce, Newton, A. C.
  • Characterisation of mechanisms correlated with reduced azole sensitivity in Mycosphaerella graminicola. (2008) Cools, H. J., Fraaije, Bart, Bean, T. P., Lucas, J. A.
  • Confidential report to Makhteshim Agan (UK) Ltd. (2008) Fraaije, Bart
  • Controlling Septoria: can azole fungicides be relied upon? (2008) Fraaije, Bart, Cools, H. J., Clark, B., Lucas, J. A.
  • Demethylation inhibitor resistance in cereal pathogens and consequences of resistance management. (2008) Fraaije, Bart, Cools, H. J., Motteram, J., Lucas, J. A.
  • Dispersal of airborne spores from plant pahtogenic fungi in cereals. (2008) Havis, N., Fraaije, Bart, Oxley, S.
  • Expression of genes encoding efflux proteins in Mycosphaerella graminicola isolates with sensitive or reduced triazole sensitivity phenotypes. (2008) Bean, T. P., Cools, H. J., Lucas, J. A., Fraaije, Bart
  • Impact of mutations in the CYP51 gene of Mycosphaerella graminicola on azole fungicide sensitivity and intrinsic protein function. (2008) Cools, H. J., Fraaije, Bart, Fernandez-Ortuno, D., Bean, T. P., Lucas, J. A.
  • Long-term dynamics in wheat of Phaeosphaeria nodorum and Mycosphaerella graminicola. (2008) Shaw, M. W., Bearchell, Sarah, Fitt, Bruce, Fraaije, Bart
  • Long-term relationships between environment and abundance of wheat of Phaeosphaeria nodorum and Mycosphaerella graminicola. (2008) Shaw, M. W., Bearchell, Sarah, Fitt, Bruce, Fraaije, Bart
  • Quantitative measurements of CYP51 alterations in populations of Mycosphaerella graminicola using pyrosequencing. (2008) Motteram, J., Cools, H. J., Gilbert, S., Fraaije, Bart
  • Re-contructing evolution of fungicide resistance and disease dynamics of cereal pathogens from crop archives. (2008) Fraaije, Bart
  • Testing of fungicide activity enhancers using Septoria leaf blotch as model. Confidential report to industrial sponsor. (2008) Bean, T. P., Fraaije, Bart
  • Understanding fungicide mixtures to control Rhynchosporium in barley and minimise resistance shifts. HGCA Project Report No. 436. (2008) Oxley, S. J. P., Burnett, F., Hunter, E, Fraaije, Bart, Cooke, L. R., Mercer, P. C., Gilchrist, A.
  • The dynamics of Rynchosporium secalis in winter and spring barley and the role of inoculum sources. (2008) Atkins, S. D., Fraaije, Bart, Lucas, J. A., Fitt, Bruce
  • The final straw: crop archives and the recent history of cereal pathosystems. (2008) Lucas, J. A., Fraaije, Bart
  • A novel substitution 1381V in the sterol 14alpha-demethylase (CYP51) of Mycosphaerella graminicola is differentially selected by azole fungicides. (2007) Fraaije, Bart, Cools, H. J., Kim, S-H., Motteram, J., Clark, W. S., Lucas, J. A.
  • Application of real-time and multiplex polymerase chain reaction assays to study leaf blotch epidemics in barley. (2007) Fountaine, J. M., Shaw, M. W., Napier, B., Ward, E., Fraaije, Bart
  • Dynamics of fungicide resistant alleles in field populations of Mycosphaerella graminicola. (2007) Fraaije, Bart
  • Effects of a strobilurin-based spray programme on disease control, green leaf area, yield and development of fungicide-resistance in Mycosphaerella graminicola in Northern Ireland. (2007) Mccartney, C., Mercer, P. C., Cooke, L. R., Fraaije, Bart
  • Evolution of fungicide resistance in UK populations of Mycosphaerella graminicola. (2007) Fraaije, Bart
  • Molecular mechanisms associated with altered azole sensitivity in Mycosphaerella graminicola. (2007) Cools, H. J., Bean, T. P., Motteram, J., Gilbert, S. R., Fraaije, Bart
  • Sterol content analysis of Mycosphaerella graminicola isolates with reduced sensitivity to triazole fungicides. (2007) Bean, T. P., Cools, H. J., Fraaije, Bart, Lucas, J. A.
  • Transcriptome profiling of the response of Mycosphaerella graminicola isolates to an azole fungicide using cDNA microarrays. (2007) Cools, H. J., Fraaije, Bart, Bean, T. P., Antoniw, John, Lucas, J. A.
  • Application of quantitative real-time PCR to monitor Rynchosporium secalis in barley cultivars. (2006) Atkins, S. D., Fountaine, J. M., Fitt, Bruce, Fraaije, Bart
  • DMI resistance: an overview. (2006) Fraaije, Bart
  • Development and field testing of fungicide anti-resistance strategies, with particular reference to strobilurin QoI group of fungicides. (HGCA Project Report No. 392). (2006) Fraaije, Bart, Burnett, F. J., Clark, W. S., Lucas, J. A.
  • Effects of Strobilurin fungicides on control of Septoria tritici blotch, green leaf area and yield of winter wheat in the light of fungicide resistance in Northern Ireland. (2006) Mccartney, C., Mercer, P. C., Cooke, L. R., Fraaije, Bart
  • Evolution of azole resistance mechanisms in UK populations of Mycosphaerella graminicola. (2006) Cools, H. J., Fraaije, Bart
  • Exploring appressorial formation in the cereal biotroph powdery mildew. (2006) Gilbert, S. R., Fraaije, Bart, Bailey, A., Cools, H. J., Lucas, J. A.
  • Fungicide resistance management strategies, using barley mildew as a model. (2006) Burnett, F. J., Clark, W. S., Fraaije, Bart, Lucas, J. A.
  • Impact of changes in the target P450 CYP51 enzyme associated with altered triazole-sensitivity in fungal pathogens of cereal crops. (2006) Cools, H. J., Fraaije, Bart, Kim, S. H., Lucas, J. A. picture_as_pdf
  • In planta expression analysis in Mycosphaerella graminicola of genes encoding efflux proteins. (2006) Bean, T. P., Cools, H. J., Fraaije, Bart, Lucas, J. A.
  • Integration of molecular diagnostics and air sampling to study plant pathogens. (2006) West, Jon, Fraaije, Bart, Motteram, J., Rogers, S. L., Lacey, M. E., Lucas, J. A.
  • Methods to detect fungicide resistance: from broth dilution to real-time PCR. (2006) Fraaije, Bart, Cools, H. J.
  • Transcriptome profiling of the response of Mycosphaerella graminicola isolates to triazole fungicides using cDNA microarrays. (2006) Cools, H. J., Antoniw, John, Bean, T. P., Fraaije, Bart
  • Transcriptome profiling of the response of Mycosphaerella graminicola isolates to triazole fungicides using cDNA microarrays. (2006) Cools, H. J., Antoniw, John, Fraaije, Bart
  • Wheat archive links long-term fungal pathogen population dynamics to air pollution. (2005) Bearchell, Sarah, Fraaije, Bart, Shaw, M. W., Fitt, Bruce
  • The role of ascospores in further spread of QoI-resistant cytochrome b alleles (G143A) in field populations of Mycosphaerella graminicola. (2005) Fraaije, Bart, Cools, H. J., Fountaine, J., Lovell, D. J., Motteram, J., West, Jon, Lucas, J. A.
  • Exploring appressorial formation in the biotrophic cereal fungus powdery mildew. (2005) Gilbert, S., Cools, H. J., Fraaije, Bart, Bailey, A., Lucas, J. A.
  • Integration of spore trapping with molecular techniques to enhance epidemiological studies. (2005) West, Jon, McCartney, H. A., Fountaine, J., Fraaije, Bart, Lee, I. K., Lucas, J. A.
  • Molecular examination of Septoria tritici isolates with reduced sensitivities to triazoles. (2005) Cools, H. J., Fraaije, Bart, Lucas, J. A.
  • Molecular mechanisms correlated with changes in triazole sensitivity in isolates of Mycosphaerella graminicola. (2005) Cools, H. J., Fraaije, Bart, Lucas, J. A.
  • QoI resistance in Mycosphaerella graminicola : role of inoculum, effect of different anti-resistance strategies and current status in the UK. (2005) Fraaije, Bart, Burnett, F., Clark, W., Motteram, J., Lucas, J. A.
  • Resistance development to QoI inhibitors in populations of Mycosphaerella graminicola in the UK. (2005) Fraaije, Bart, Burnett, F. J., Clark, W. S., Motteram, J., Lucas, J. A.
  • Strobilurin resistance in Septoria tritici in the UK. (HGCA topic sheet No. 69). (2005) Clark, W., Fraaije, Bart
  • Testing an experimental fungicide for in vitro activity against Mycosphaerella graminicola (anamorph Septoria tritici ) (Confidential report for Cropsolution Inc). (2005) Lucas, J. A., Bean, T., Cools, H. J., Fraaije, Bart
  • Using cDNA microarrays to profile the response of Mycosphaerella graminicola to triazole fungicides. (2005) Cools, H. J., Fraaije, Bart, Keon, J. P. R., Antoniw, John, Lucas, J. A.
  • Evolution of QoI resistance in populations of Mycosphaerella graminocola. (2004) Fraaije, Bart, Lucas, J. A.
  • Molecular mechanisms conferring reduced sensitivities to triazoles in UK isolates of Septoria tritici. (2004) Cools, H. J., Fraaije, Bart, Lucas, J. A.
  • Plant pathogen diagnostics: immunological and nucleic acid-based approaches. (2004) Ward, E., Foster, S. J., Fraaije, Bart, McCartney, H. A. picture_as_pdf
  • Molecular diagnostics for fungal plant pathogens. (2003) McCartney, H. A., Foster, S. J., Fraaije, Bart, Ward, E. picture_as_pdf
  • Peduncle rot of dwarf wheat caused by Rhizoctonia cerealis. (2003) Lovell, D. J., Parker, S. R., Baldwin, S., Fraaije, Bart
  • QoI resistance development in populations of cereal pathogens in the UK. (2003) Fraaije, Bart, Lucas, J. A., Clark, W. S., Burnett, F. J.
  • Following the dynamics of strobilurin resistance in Blumeria graminis f.sp. tritici using quantitative allele-specific real-time PCR measurements with the fluorescent dye SYBR Green 1. (2002) Fraaije, Bart, Butters, J. A., Coelho, J. M., Jones, D. R., Hollomon, D. W.
  • Quantitative PCR monitoring of the effect of azoxystrobin treatments on Mycosphaerella graminicola epidemics in the field. (2002) Rohel, E. A., Laurent, P., Fraaije, Bart, Cavelier, N., Hollomon, D. W. picture_as_pdf
  • Resistance in wheat powdery mildew to strobilurin fungicides: effects of dose rate, frequency and mixtures (Final report to Defra on project PT0226). (2002) Fraaije, Bart
  • Septoria epidemics on wheat: combined use of visual assessment and PCR-based diagnostics to identify mechanisms of disease escape. (2002) Fraaije, Bart, Lovell, D. J., Baldwin, S.
  • Exploring infection of wheat and carbohydrate metabolism in Mycosphaerella graminocola transformants with differentially regulated green fluorescent protein expression. (2001) Rohel, E. A., Payne, A. C., Fraaije, Bart, Hollomon, D. W.
  • Novel DNA diagnostic technology in plant disease control using Septoria tritici as a model. (HGCA Project Report No. 245). (2001) Fraaije, Bart, Hollomon, D. W.
  • Occurrence and molecular characterization of strobilurin resistance in cucumber powdery mildew and downy mildew. (2001) Ishii, H., Fraaije, Bart, Sugiyama, T., Noguchi, K., Nishimura, K., Takeda, T., Amano, T., Hollomon, D. W.
  • PCR-based assays to assess wheat varietal resistance to blotch (Septoria tritici and Stagonospora nododrum ) and rust (Puccinia striiformis and Puccinia recondita) diseases. (2001) Fraaije, Bart, Lovell, D. J., Coelho, J. M., Baldwin, S., Hollomon, D. W. picture_as_pdf
  • In planta genotyping of Erysiphe graminis f. sp. tritici isolates for strobilurin-resistance using a fluorometric allele-specific PCR assay. (2000) Fraaije, Bart, Butters, J. A., Hollomon, D. W.
  • In planta genotyping of Erysiphe graminis f. sp. tritici isolates for strobilurin-resistance using a fluorometric allele-specific PCR assay. (2000) Fraaije, Bart, Butters, J. A., Hollomon, D. W.