A - Papers appearing in refereed journals
Saintennac, C., Lee, W. S., Cambon, F., Rudd, J. J., King, R., Marande, W., Powers, S. J., Berges, H., Phillips, A. L., Uauy, C., Hammond-Kosack, K. E., Langin, T. and Kanyuka, K. 2018. Wheat receptor-kinase-like protein Stb6 controls gene-for-gene resistance to fungal pathogen Zymoseptoria tritici. Nature Genetics. 50, pp. 368-374. https://doi.org/10.1038/s41588-018-0051-x
Authors | Saintennac, C., Lee, W. S., Cambon, F., Rudd, J. J., King, R., Marande, W., Powers, S. J., Berges, H., Phillips, A. L., Uauy, C., Hammond-Kosack, K. E., Langin, T. and Kanyuka, K. |
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Abstract | Deployment of fast-evolving disease-resistance genes is one of the most successful strategies used by plants to fend off pathogens. In gene-for-gene relationships, most cloned disease-resistance genes encode intracellular nucleotide-binding leucine-rich-repeat proteins (NLRs) recognizing pathogensecreted isolate-specific avirulence (Avr) effectors delivered to the host cytoplasm. This process often triggers a localized hypersensitive response, which halts further disease development. Here we report the map-based cloning of the wheat Stb6 gene and demonstrate that it encodes a conserved wallassociated receptor kinase (WAK)-like protein, which detects the presence of a matching apoplastic effector and confers pathogen resistance without a hypersensitive response. This report demonstrates gene-for-gene disease resistance controlled by this class of proteins in plants. Moreover, Stb6 is, to our knowledge, the first cloned gene specifying resistance to Zymoseptoria tritici, an important foliar fungal pathogen affecting wheat and causing economically damaging septoria tritici blotch (STB) disease. |
Year of Publication | 2018 |
Journal | Nature Genetics |
Journal citation | 50, pp. 368-374 |
Digital Object Identifier (DOI) | https://doi.org/10.1038/s41588-018-0051-x |
Open access | Published as ‘gold’ (paid) open access |
Funder | Biotechnology and Biological Sciences Research Council |
Funder project or code | Designing Future Wheat (DFW) [ISPG] |
DFW - Designing Future Wheat - Work package 2 (WP2) - Added value and resilience | |
20:20 Wheat [ISPG] | |
[20:20 Wheat] Maximising yield potential of wheat | |
[20:20 Wheat] Protecting yield potential of wheat | |
Publisher's version | Copyright license CC BY |
Supplemental file | Copyright license CC BY |
Supplemental file | Copyright license Publisher copyright |
Output status | Published |
Publication dates | |
Online | 12 Feb 2018 |
Publication process dates | |
Accepted | 02 Jan 2018 |
Publisher | Nature Publishing Group |
ISSN | 1061-4036 |
Permalink - https://repository.rothamsted.ac.uk/item/84675/wheat-receptor-kinase-like-protein-stb6-controls-gene-for-gene-resistance-to-fungal-pathogen-zymoseptoria-tritici