The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity - a randomised, double-blind, placebo-controlled, international, multicentre study

A - Papers appearing in refereed journals

De Graaf, M. C. G., Lawton, C. L., Croden, F., Smolinska, A., Winkens, B., Hesselink, M. A. M., Van Rooy, G., Weegels, P. L., Shewry, P. R., Houghton, L. A., Witteman, B. J. M., Keszthelyi, D., Brouns, F. J. P. H., Dye, L. and Jonkers, D. M. A. E. 2023. The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity - a randomised, double-blind, placebo-controlled, international, multicentre study. Lancet Gastroenterology and Hepatology. 9 (2), pp. 110-123. https://doi.org/10.1016/S2468-1253(23)00317-5

AuthorsDe Graaf, M. C. G., Lawton, C. L., Croden, F., Smolinska, A., Winkens, B., Hesselink, M. A. M., Van Rooy, G., Weegels, P. L., Shewry, P. R., Houghton, L. A., Witteman, B. J. M., Keszthelyi, D., Brouns, F. J. P. H., Dye, L. and Jonkers, D. M. A. E.
Abstract

Many individuals without coeliac disease or wheat allergy reduce their gluten intake because they believe that gluten causes their gastrointestinal symptoms. Symptoms could be affected by negative expectancy. Therefore, we aimed to investigate the effects of expectancy versus actual gluten intake on symptoms in people with non-coeliac gluten sensitivity (NCGS).

Year of Publication2023
JournalLancet Gastroenterology and Hepatology
Journal citation9 (2), pp. 110-123
Digital Object Identifier (DOI)https://doi.org/10.1016/S2468-1253(23)00317-5
Open accessPublished as non-open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeWell on wheat
Output statusPublished
Publication dates
Online28 Nov 2023
PublisherElsevier Science Inc
Elsevier
ISSN2468-1253

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