Increased bioavailability of phenolic acids and enhanced vascular function following intake of feruloyl esterase-processed high fibre bread: A randomized, controlled, single blind, crossover human intervention trial
Turner, A. L., Michaelson, Louise, Shewry, Peter, Lovegrove, Alison and Spencer, J. P. E.
(2020)
Increased bioavailability of phenolic acids and enhanced vascular function following intake of feruloyl esterase-processed high fibre bread: A randomized, controlled, single blind, crossover human intervention trial.
Clinical Nutrition, 40.
pp. 788-795.
10.1016/j.clnu.2020.07.026
Clinical trial data have indicated an association between wholegrain consumption and a reduction in surrogate markers of cardiovascular disease. Phenolics present in wholegrain bound to arabinoxylan fibre may contribute these effects, particularly when released enzymatically from the fiber prior to ingestion. The aim of the present study was therefore to determine whether the intake of high fibre bread containing higher free ferulic acid (FA) levels (enzymatically released during processing) enhances human endothelium-dependent vascular function.
| Item Type | Article |
|---|---|
| Open Access | Not Open Access |
| Keywords | Bioavailability, Ferulic acid, Vascular function, High fibre bread, Human intervention, Feruloyl esterase |
| Project | Designing Future Wheat WP2.2 |
| Date Deposited | 05 Dec 2025 10:26 |
| Last Modified | 19 Dec 2025 14:53 |
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