Purification and functional characterisation of COMATOSE a peroxisomal ABC transporter from Arabidopsis thaliana
Project (past)
| Project dates | 01 Jun 2008 to end of 30 Jun 2011 |
|---|---|
| Researchers | |
| Principal Investigator | Freddie Theodoulou |
| Project number | S4916 |
| 4916 | |
| Department | Biological Chemistry (BCH) Division |
| Research fish code | BB/F007108/1 |
| Grant ID | BB/F007108/1 |
Outputs
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Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but are both required for activity
A - Papers appearing in refereed journals
Nyathi, Y., Zhang, X., Baldwin, J. M., Bernhardt, K., Johnson, B., Baldwin, S. A., Theodoulou, F. L. and Baker, A. 2012. Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but are both required for activity. FEBS Letters. 586 (16), pp. 2280-2286. https://doi.org/10.1016/j.febslet.2012.05.065
Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance
A - Papers appearing in refereed journals
Kemp, S., Theodoulou, F. L. and Wanders, R. J. A. 2011. Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance. British Journal Of Pharmacology. 164 (7), pp. 1753-1766. https://doi.org/10.1111/j.1476-5381.2011.01435.x
Conservation of targeting but divergence in function and quality control of peroxisomal ABC transporters: an analysis using cross-kingdom expression
A - Papers appearing in refereed journals
Zhang, X., De Marcos Lousa, C., Schutte-Lensink, N., Ofman, R., Wanders, R. J., Baldwin, S. A., Baker, A., Kemp, S. and Theodoulou, F. L. 2011. Conservation of targeting but divergence in function and quality control of peroxisomal ABC transporters: an analysis using cross-kingdom expression. Biochemical Journal. 436, pp. 547-557. https://doi.org/10.1042/BJ20110249
Editorial: The next hundred years
G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2011. Editorial: The next hundred years. Biochemist. 33(1), p. 3.
Peroxisomal transport systems: roles in signaling and metabolism
B - Book chapters etc edited externally
Theodoulou, F. L., Zhang, X., De Marcos Lousa, C., Nyathi, Y. and Baker, A. 2011. Peroxisomal transport systems: roles in signaling and metabolism. in: Geisler, M. and Venema, K. (ed.) Transporters and pumps in plant signaling Springer, Berlin. pp. 327-351
Editorial: The student issue
G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2010. Editorial: The student issue. Biochemist. 32(5), p. 5.
Editorial: Christmas cheer
G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2010. Editorial: Christmas cheer. The Biochemist. 32(6), p. 3.
The Arabidopsis peroxisomal ABC transporter, Comatose, complements the Saccharomyces cerevisiae pxa1 pxa2delta mutant for metabolism of long-chain fatty acids and exhibits fatty acyl-CoA-stimulated ATPase activity
A - Papers appearing in refereed journals
Nyathi, Y., De Marcos Lousa, C., Van Roermund, C. W., Wanders, R. J. A., Johnson, B., Baldwin, S. A., Theodoulou, F. L. and Baker, A. 2010. The Arabidopsis peroxisomal ABC transporter, Comatose, complements the Saccharomyces cerevisiae pxa1 pxa2delta mutant for metabolism of long-chain fatty acids and exhibits fatty acyl-CoA-stimulated ATPase activity. Journal of Biological Chemistry. 285, pp. 29892-29902. https://doi.org/10.1074/jbc.M110.151225
The genome - 10 years on
G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2010. The genome - 10 years on. Biochemist. August 2010, p. 3.
The carbon cost of conferences
G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2010. The carbon cost of conferences. Biochemist. June 2010, p. 3.
The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters
A - Papers appearing in refereed journals
De Marcos Lousa, C., Dietrich, D., Johnson, B., Baldwin, S. A., Holdsworth, M. J., Theodoulou, F. L. and Baker, A. 2009. The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters. Communicative and Integrative Biology. 2 (2), pp. 97-99. https://doi.org/10.4161/cib.7621
Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series
A - Papers appearing in refereed journals
Dietrich, D., Schmuths, H., De Marcos Lousa, C., Baldwin, J. M., Baldwin, S. A., Baker, A., Theodoulou, F. L. and Holdsworth, M. J. 2009. Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series. Molecular Biology Of The Cell. 20, pp. 530-543. https://doi.org/10.1091/mbc.E08-07-0745