Charlotte Lomax

NameCharlotte Lomax
Job titleScientific Specialist - Mass Spectroscopist
Email addresscharlotte.lomax@rothamsted.ac.uk
DepartmentPlant Sciences and the Bioeconomy
Research clusterCAS: Molecular Discovery
OfficeHarpenden

Research outputs

Breeding for novel chemistry in willow: new hetero Diels-Alder cyclodimers based on arbusculoidin and salicortin suggest parallel biosynthetic pathways

Noleto-Dias, C., Lomax, C., Bellisai, A., Ruvo, G., Harflett, C., Macalpine, W. J., Hanley, S. J., Beale, M. H. and Ward, J. L. 2024. Breeding for novel chemistry in willow: new hetero Diels-Alder cyclodimers based on arbusculoidin and salicortin suggest parallel biosynthetic pathways. Plants - Basel. 13 (12), p. 1609. https://doi.org/10.3390/plants13121609

Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds

Menard, G. N., Langdon, M., Bhunia, R., Shankhapal, A., Noleto-Dias, C., Lomax, C., Ward, J. L., Kurup, S. and Eastmond, P. J. 2022. Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds. Metabolic Engineering. 70, pp. 196-205. https://doi.org/10.1016/j.ymben.2022.01.016

A willow UDP-glycosyltransferase involved in salicinoid biosynthesis

Kulasekaran, S., Cerezo-Medina, S., Harflett, C., Lomax, C., DeJong, F., Rendour, A., Ruvo, G., Hanley, S. J., Beale, M. H. and Ward, J. L. 2020. A willow UDP-glycosyltransferase involved in salicinoid biosynthesis. Journal of Experimental Botany. 72 (5), p. 1634–1648. https://doi.org/10.1093/jxb/eraa562

Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides

Eskandari, H., Ghanadian, M., Noleto-Dias, C., Lomax, C., Tawfike, A., Christiansen, G., Sutherland, D. S., Ward, J. L., Mohammad-Beigi, H. and Otzen, D. E. 2020. Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides. ACS Chemical Neuroscience. 11 (19), pp. 3161-3173. https://doi.org/10.1021/acschemneuro.0c00528

Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy.

Ward, J. L., Wu, Y., Harflett, C., Onafuye, H., Corol, D. I., Lomax, C., Macalpine, W. J., Cinatl, J., Wass, M. N., Michaelis, M. and Beale, M. H. 2020. Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy. Scientific Reports. 10, p. 6477. https://doi.org/10.1038/s41598-020-63349-1

Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

Mohammed-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A., Shafer, N.P., Amiri-Nowdijeh, A., Eskandari, E., Moller, I.M., Hosseini-Mazinani, M., Christiansen, G., Ward, J. L., Morshedi, D. and Otzen, D.E 2019. Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. Journal of Biological Chemistry. 294, pp. 4215-4232. https://doi.org/10.1074/jbc.RA118.005723

Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine

Noleto-Dias, C., Ward, J. L., Bellisai, A., Lomax, C. and Beale, M. H. 2018. Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine. Fitoterapia. 127 (June), pp. 166-172. https://doi.org/10.1016/j.fitote.2018.02.009

Investigating the origin and transport of methylated arsenic species in plants

Lomax, C. 2013. Investigating the origin and transport of methylated arsenic species in plants. F - Theses

Methylated arsenic species in plants originate from soil microorganisms

Lomax, C., Liu, W-J., Wu, Liyou, Xue, K., Xiong, J., Zhou, J., McGrath, S. P., Meharg, A. A., Miller, A. J. and Zhao, F-J. 2012. Methylated arsenic species in plants originate from soil microorganisms. New Phytologist. 193 (3), pp. 665-672. https://doi.org/10.1111/j.1469-8137.2011.03956.x

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