Chlorotoluron metabolism in resistant and susceptible biotypes of the grass weed Alopecurus mysuroides

A - Papers appearing in refereed journals

Hyde, R. J., Hallahan, D. L. and Bowyer, J. R. 1996. Chlorotoluron metabolism in resistant and susceptible biotypes of the grass weed Alopecurus mysuroides. Pesticide Science. 47 (2), pp. 185-190.

AuthorsHyde, R. J., Hallahan, D. L. and Bowyer, J. R.
Abstract

The metabolism of the herbicide chlorotoluron by susceptible and resistant biotypes of the grass weed, Alopecurus myosuroides, was examined. After administration of radiolabelled herbicide to leaves, metabolites were extracted and analysed. The metabolites identified consisted of mono-demethylated-, di-demethylated- and ring methyl-hydroxylated chlorotoluron. Metabolism was more extensive in the resistant biotype, yielding principally the non-phytotoxic ring methyl-hydroxylated metabolite. The metabolites observed are characteristic of the activity of cytochrome P450 mixed-function oxygenase action. The specific cytochrome P450 inhibitor, 1-aminobenzotriazole, reduced accumulation of the ring methyl-hydroxylated metabolite in the resistant biotype.

KeywordsAgronomy; Entomology
Year of Publication1996
JournalPesticide Science
Journal citation47 (2), pp. 185-190
Open accessPublished as non-open access
Funder project or code215
432
Project: 011528
ISSN0031613X
PublisherWiley

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