Paralysis of the honey bee, Apis mellifera Linnaeus

Chronic bee paralysis virus (CBPV) was differentiated from acute bee paralysis virus (ABPV) by the symptoms it caused when injected into normal bees and by histological and serological means. It was isolated from naturally paralyzed bees from various parts of Britain and from Hong Kong, and, in one instance, from normal bees. Overt disease disappeared when the queens of naturally diseased colonies were replaced with others from normal colonies. Normal bees in colonies or cages were resistant to chronic paralysis when sprayed or fed with CBPV. Bees injected with CBPV transmitted it in the food they passed to normal bees.