Can oils derived from genetically-modified plants replace fish oil as a source of long chain n-3 polyunsaturated fatty acids in the human diet?

Repository project

Project dates01 Jul 2016 to end of 31 Mar 2020
Researchers
Principal InvestigatorJohnathan Napier
FunderBiotechnology and Biological Sciences Research Council
Project numberS5517
5517
DepartmentPlant Sciences
Research fish codeBB/N01412X/1
Grant IDBB/N01412X/1

Outputs

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Genetically modified plants are an alternative to oily fish for providing n-3 polyunsaturated fatty acids in the human diet: A summary of the findings of a Biotechnology and Biological Sciences Research Council funded project

A - Papers appearing in refereed journals
West, A. L., Miles, E. A., Lillicrop, K. A., Napier, J. A., Calder, P. C. and Burdge, G. C. 2020. Genetically modified plants are an alternative to oily fish for providing n-3 polyunsaturated fatty acids in the human diet: A summary of the findings of a Biotechnology and Biological Sciences Research Council funded project. Nutrition Bulletin. 46 (1), pp. 60-68. https://doi.org/10.1111/nbu.12478

Dietary supplementation with seed oil from transgenic Camelina sativa induces similar increments in plasma and erythrocyte DHA and EPA to fish oil in healthy humans

A - Papers appearing in refereed journals
West, A. L., Miles, E. A., Lillycrop, K. A., Han, L., Napier, J. A., Clader, P. C. and Burdge, G. C. 2020. Dietary supplementation with seed oil from transgenic Camelina sativa induces similar increments in plasma and erythrocyte DHA and EPA to fish oil in healthy humans. British Journal Of Nutrition. https://doi.org/10.1017/S0007114520002044

Differential postprandial incorporation of 20:5n-3 and 22:6n-3 into individual plasma triacylglycerol and phosphatidylcholine molecular species in humans

A - Papers appearing in refereed journals
West, A. L., Michaelson, L. V., Miles, E. A., Haslam, R. P., Lillycrop K. A., Georgescu, R., Han, L., Sayanova, O. V., Napier, J. A., Calder, P. C. and Burdge, G. C. 2020. Differential postprandial incorporation of 20:5n-3 and 22:6n-3 into individual plasma triacylglycerol and phosphatidylcholine molecular species in humans. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1865 (8), p. 158710. https://doi.org/10.1016/j.bbalip.2020.158710

Postprandial incorporation of EPA and DHA from transgenic Camelina sativa oil into blood lipids is equivalent to that from fish oil in healthy humans

A - Papers appearing in refereed journals
West, A. L., Miles, E.A., Lillycrop K. A., Han, L., Sayanova, O. V., Napier, J. A. and Calder, P. C. 2019. Postprandial incorporation of EPA and DHA from transgenic Camelina sativa oil into blood lipids is equivalent to that from fish oil in healthy humans. British Journal Of Nutrition. pp. 1-27. https://doi.org/10.1017/S0007114519000825

Nutritional Evaluation of an EPA-DHA Oil from Transgenic Camelina sativa in Feeds for Post-Smolt Atlantic Salmon (Salmo salar L.)

A - Papers appearing in refereed journals
Betancor, M. B., Sprague, M., Sayanova, O. V., Usher, S., Metochis, C., Campbell, P. J., Napier, J. A. and Tocher, D. R. 2016. Nutritional Evaluation of an EPA-DHA Oil from Transgenic Camelina sativa in Feeds for Post-Smolt Atlantic Salmon (Salmo salar L.). PLOS ONE. 11 (7). https://doi.org/10.1371/journal.pone.0159934