EDM2 is required for RPP7 -dependent disease resistance in Arabidopsis and affects RPP7 transcript levels

Eulgem, T., Tsuchiya, T., Wang, X-J., Beasley, B., Cuzick, A., Tor, M., Zhu, T., Mcdowell, J. M., Holub, E. and Dangl, J. L. 2007. EDM2 is required for RPP7 -dependent disease resistance in Arabidopsis and affects RPP7 transcript levels. The Plant Journal. 49, pp. 829-839. https://doi.org/10.1111/j.1365-313X.2006.02999.x

Related outputs

PHI-base - The multi-species Pathogen-Host Interaction Database in 2025

A - Papers appearing in refereed journals

Urban, M., Cuzick, A., Seager, J., Nonavinakere, N., Sahu, J., Sahu, P., Iyer, V. L., Khamari, L., Martinez, M. C. and Hammond-Kosack, K. E. 2024. PHI-base - The multi-species Pathogen-Host Interaction Database in 2025. Nucleic Acids Research. https://doi.org/10.1093/nar/gkae1084

The Gene Ontology knowledgebase in 2023

A - Papers appearing in refereed journals

Aleksander, S. A., Balhoff, J., Carbon, S., Cherry, J. M., Drabkin, H. J., Ebert, D., Feuermann, M., Gaudet, P., Harris, N. L., Hill, D. P., Lee, R., Mi, H., Moxon, S., Mungall, C. J., Muruganugan, A., Mushayahama, T., Sternberg, P. W., Thomas, P. D., Auken, K. V., Ramsey, J., Siegele, D. A., Chisholm, R. L., Fey, P., Aspromonte, M. C., Nugnes, M. V., Quaglia, F., Tosatto, S., Giglio, M., Nadendla, S., Antonazzo, G., Attrill, H., Santos, G. D., Marygold, S., Strelets, V., Tabone, C. J., Thurmond, J., Zhou, P., Ahmed, S. H., Asanitthong, P., Buitrago, D. L., Erdol, M. N., Gage, M. C., Kadhum, M. A., Li, K. Y. C., Long, M., Michalak, A., Pesala, A., Pritazahra, A., Saverimuttu, S. C. C., Su, R., Thurlow, K. E., Lovering, R. C., Logie, C., Oliferenko, S., Blake, J., Christie, K., Corbani, L., Dolan, M. E., Drabkin, H. J., Hill, D. P., Ni, L., Sitnikov, D., Smith, C., Cuzick, A., Seager, J., Cooper, L., Elser, J., Jaiswal, P., Gupta, P., Jaiswal, P., Naithani, S., Lera-Ramirez, M., Rutherford, K., Wood, V., Pons, J. L. D., Dwinell, M. R., Hayman, G. T., Kaldunski, M. L., Kwitek, A. E., Laulederkind, S. J. F., Tutaj, M. A., Vedi, M., Wang, S., D'Eustachio, P., Aimo, L., Axelsen, K., Bridge, A., Hyka-Nouspikel, N., Morgat, A., Aleksander, S. A., Cherry, J. M., Engel, S. R., Karra, K., Miyasato, S. R., Nash, R. S., Skrzypek, M. S., Weng, S., Wong, E. D., Bakker, E., Berardini, T. Z., Reiser, L., Auchincloss, A., Axelsen, K., Argoud-Puy, G., Blatter, M., Boutet, E., Breuza, L., Bridge, A., Casals-Casas, C., Coudert, E., Estreicher, A., Famiglietti, M. L., Feuermann, M., Gos, A., Gruaz-Gumowski, N., Hulo, C., Hyka-Nouspikel, N., Jungo, F., Mercier, P. L., Lieberherr, D., Masson, P., Morgat, A., Pedruzzi, I., Pourcel, L., Poux, S., Rivoire, C., Sundaram, S., Bateman, A., Bowler-Barnett, E., Bye-A-Jee, H., Denny, P., Ignatchenko, A., Ishtiaq, R., Lock, A., Lussi, Y., Magrane, M., Martin, M. J., Orchard, S., Raposo, P., Speretta, E., Tyagi, N., Warner, K., Zaru, R., Diehl, A. D., Lee, R., Chan, J., Diamantakis, S., Raciti, D., Zarowiecki, M., Fisher, M., James-Zorn, C., Ponferrada, V., Zorn, A., Ramachandran, S., Ruzicka, L., Westerfield, M. and Gene Ontology Consortium 2023. The Gene Ontology knowledgebase in 2023. Genetics. 244 (1), p. iyad031. https://doi.org/10.1093/genetics/iyad031

A framework for community curation of interspecies interactions literature

A - Papers appearing in refereed journals

Cuzick, A., Seager, J., Wood, V., Urban, M., Rutherford, K. and Hammond-Kosack, K. E. 2023. A framework for community curation of interspecies interactions literature. eLife. 12, p. e84658. https://doi.org/10.7554/eLife.84658

Ensembl Genomes 2022: an expanding genome resource for non-vertebrates

A - Papers appearing in refereed journals

Yates, A. D., Allen, J., Amode, R. M., Azov, A. G., Barba, M., Becerra, A., Bhai, J., Campbell, L. I., Carbajo Martinez, M., Chakiachvili, M, Chougule, K., Christensen, M., Contreras-Moreira, B., Cuzick, A., Fioretto, L. D. R., Davis, P., Silva, N. H. D., Diamantakis, S., Dyer, S., Elser, J., Filippi, C. V., Gall, A., Grigoriadis, D., Guijarro-Clarke, C., Gupta, P., Hammond-Kosack, K. E., Howe, K. L., Jaiswal, P., Kaikala, V., Kumar, V., Kumari, S., Langridge, N., Le, T., Luypaert, M., Maslen, G. L., Maurel, T., Moore, B., Muffato, M., Mushtaq, A., Naamati, G., Naithani, S., Olson, A., Parker, A., Paulini, M., Pedro, H., Perry, E., Preece, J., Quinton-Tulloch, M., Rodgers, F., Rosello, M., Ruffier, M., Seager, J., Sitnik, V., Szpak, M., Tate, J., Tello-Ruiz, M. K., Trevanion, S. J., Urban, M., Ware, D., Wei, S., Williams, G., Winterbottom, A., Zarowiecki, M., Finn, R. D. and Flicek, P. 2022. Ensembl Genomes 2022: an expanding genome resource for non-vertebrates. Nucleic Acids Research. 50 (D1), pp. D996-D1003. https://doi.org/10.1093/nar/gkab1007

PHI-base in 2022 a multi-species phenotype database for Pathogen–Host Interactions

A - Papers appearing in refereed journals

Urban, M., Cuzick, A., Seager, J., Wood, V., Rutherford, K., Venkatesh, S. Y., Sahu, J., Iyer, S. V., Khamari, L., De Silva, N., Martinez, M. C., Pedro, H., Yates, A. D. and Hammond-Kosack, K. E. 2021. PHI-base in 2022 a multi-species phenotype database for Pathogen–Host Interactions. Nucleic Acids Research. 50, pp. D837-D847. https://doi.org/10.1093/nar/gkab1037

Ensembl Genomes 2020-enabling non-vertebrate genomic research

A - Papers appearing in refereed journals

Cuzick, A., Howe, K. L., Contreras-Moreira, B., Silva, N. D., Maslen, G., Akanni, W., Allen, J., Alvarez-Jarreta, J., Barba, M., Bolser, D. M., Cambell, L., Carbajo, M., Chakiachvili, M., Christensen, M., Cummins, C., Cuzick, A., Davis, P., Fexova, S., Gall, A., George, N., Gil, L., Gupta, P., Hammond-Kosack, K. E., Haskell, E., Hunt, S. E., Jaiswal, P., Janacek, S. H., Kersey, P. J., Langridge, N., Maheswari, U., Maurel, T., McDowall, M. D., Moore, B., Muffato, M., Naamati, G., Naithani, S., Olson, A., Papatheodorou, I., Patricio, M., Paulini, M., Pedro, H., Perry, E., Preece, J., Rosello, M., Russell, M., Sitnik, V., Staines, D. M., Stein, J., Tello-Ruiz, M. K., Trevanion, S. J., Urban, M., Wei, S., Ware, D., Williams, G., Yates, A. D. and Flicek, P. 2020. Ensembl Genomes 2020-enabling non-vertebrate genomic research. Nucleic Acids Research. 48 (D1), pp. D689-D695. https://doi.org/10.1093/nar/gkz890

The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species.

A - Papers appearing in refereed journals

Shefchek, K. A., Harris, N. L., Gargano, M., Matentzoglu, N., Unni, D., Brush, M., Keith, D., Conlin, T., Vasilevsky, N., Zhang, X. A., Balhoff, J. P., Babb, L., Bello, S. M., Blau, H., Bradford, Y., Carbon, S., Carmody, L., Chan, L. E., Cipriani, V., Cuzick, A., Rocca, M. D., Dunn, N., Essaid, S., Fey, P., Grove, C., Gourdine, J., Hamosh, A., Harris, M., Helbig, I., Hoatlin, M., Joachimiak, M., Jupp, S., Lett, K. B., Lewis, S. E., McNamara, C., Pendlington, Z. M., Pilgrim, C., Putman, T., Ravanmehr, V., Reese, J., Riggs, E., Robb, S., Roncaglia, P., Seager, J., Segerdell, E., Similuk, M., Storm, A. L., Thaxon, C., Thessen, A., Jacobsen, J. O. B., McMurry, J. A., Groza, T., Köhler, S., Smedley, D., Robinson, P. N., Mungall, C. J., Haendel, M. A., Munoz-Torres, M. C. and Osumi-Sutherland, D. 2020. The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species. Nucleic Acids Research. 48 (D1), p. D704–D715. https://doi.org/10.1093/nar/gkz997

PHI-base - the Pathogen–Host Interactions database

A - Papers appearing in refereed journals

Urban, M., Cuzick, A., Seager, J., Wood, V., Rutherford, K., De Silva, N., Venkatesh, S. Y, Martinez, M. C., Pedro, H., Yates, A. D., Hassani-Pak, K. and Hammond-Kosack, K. E. 2020. PHI-base - the Pathogen–Host Interactions database . Nucleic Acids Research. 48 (Database issue D1), pp. D613-D620. https://doi.org/10.1093/nar/gkz904

The Arabidopsis RRM domain protein EDM3 mediates race-specific disease resistance by controlling H3K9me2-dependent alternative polyadenylation of RPP7 immune receptor transcripts.

A - Papers appearing in refereed journals

Lai, Y., Cuzick, A., Lu, X., Wang, J., Katiyar, N., Tsuchiya, T., Le Roch, K., McDowell, J., Holub, E. and Eulgem, T. 2019. The Arabidopsis RRM domain protein EDM3 mediates race-specific disease resistance by controlling H3K9me2-dependent alternative polyadenylation of RPP7 immune receptor transcripts. The Plant Journal. 97 (4), pp. 646-660. https://doi.org/10.1111/tpj.14148

PHI-base: a new interface and further additions for the multi-species pathogen–host interactions database

A - Papers appearing in refereed journals

Urban, M., Cuzick, A., Rutherford, K., Irvine, A. G., Pedro, H., Pant, R., Sadanadan, V., Khamari, L., Billal, S., Mohanty, Sagar and Hammond-Kosack, K. E. 2017. PHI-base: a new interface and further additions for the multi-species pathogen–host interactions database. Nucleic Acids Research. 45 (D1), pp. D604-D610. https://doi.org/10.1093/nar/gkw1089

Using the phenotypic information in the pathogen-host interactions database (PHI-BASE) to explore Fusarium and Magnaporthe genomes, transcriptomes and proteomes

C1 - Edited contributions to conferences/learned societies

Urban, M., Irvine, A., Cuzick, A. and Hammond-Kosack, K. E. 2016. Using the phenotypic information in the pathogen-host interactions database (PHI-BASE) to explore Fusarium and Magnaporthe genomes, transcriptomes and proteomes. Proceedings 5th ISFHB - 2nd IWWB Symposium, 5-10, Florianopolis, Brasil.

PhytoPath: an integrative resource for plant pathogen genomics

A - Papers appearing in refereed journals

Pedro, H., Maheswari, U., Urban, M., Irvine, A. G., Cuzick, A., Mcdowall, M. D., Staines, D. M., Kulesha, E., Hammond-Kosack, K. E. and Kersey, P. J. 2016. PhytoPath: an integrative resource for plant pathogen genomics. Nucleic Acids Research. 44 (D1), pp. D688-D693. https://doi.org/10.1093/nar/gkv1052

Using the pathogen-host interactions database (PHI-base) to investigate plant pathogen genomes and genes implicated in virulence

A - Papers appearing in refereed journals

Urban, M., Irvine, A. G., Cuzick, A. and Hammond-Kosack, K. E. 2015. Using the pathogen-host interactions database (PHI-base) to investigate plant pathogen genomes and genes implicated in virulence. Frontiers in Plant Science. 6, p. 605. https://doi.org/10.3389/fpls.2015.00605

Functional evaluation of plant defence signalling against Fusarium graminearum and F. culmorum in Arabidopsis floral tissue

C2 - Non-edited contributions to conferences

Hammond-Kosack, K. E., Freeman, A., Desmouceaux, N., Urban, M. and Cuzick, A. 2009. Functional evaluation of plant defence signalling against Fusarium graminearum and F. culmorum in Arabidopsis floral tissue. Abstracts 14th International Congress on Molecular Plant-Microbe Interactions, Quebec, 19-23 July 2009 .

Molecular and genetic studies on Fusarium Ear Blight disease of wheat

C2 - Non-edited contributions to conferences

Hammond-Kosack, K. E., Kanyuka, K., Brown, N. A., Beacham, A. M., Cuzick, A., Antoniw, J. F. and Urban, M. 2009. Molecular and genetic studies on Fusarium Ear Blight disease of wheat. Abstracts 2009 National Fusarium Head Blight Forum, Orlando, 7-9 December 2009 .

Lack of the plant signalling component SGT1b enhances disease resistance to Fusarium culmorum in Arabidopsis buds and flowers

A - Papers appearing in refereed journals

Cuzick, A., Maguire, K. and Hammond-Kosack, K. E. 2009. Lack of the plant signalling component SGT1b enhances disease resistance to Fusarium culmorum in Arabidopsis buds and flowers. New Phytologist. 181, pp. 901-912. https://doi.org/10.1111/j.1469-8137.2008.02712.x

NPR1 and EDS11 contribute to host resistance against Fusarium culmorum in Arabidopsis buds and flowers

A - Papers appearing in refereed journals

Cuzick, A., Lee, S., Gezan, S. and Hammond-Kosack, K. E. 2008. NPR1 and EDS11 contribute to host resistance against Fusarium culmorum in Arabidopsis buds and flowers. Molecular Plant Pathology. 9 (5), pp. 697-704. https://doi.org/10.1111/J.1364-3703.2008.00488.X

Fusarium graminearum gene deletion mutants map1 and tri5 reveal similarities and differences in the pathogenicity requirements to cause disease on Arabidopsis and wheat floral tissue

A - Papers appearing in refereed journals

Cuzick, A., Urban, M. and Hammond-Kosack, K. E. 2008. Fusarium graminearum gene deletion mutants map1 and tri5 reveal similarities and differences in the pathogenicity requirements to cause disease on Arabidopsis and wheat floral tissue. New Phytologist. 177 (4), pp. 990-1000. https://doi.org/10.1111/j.1469-8137.2007.02333.x

Functional evaluation of plant defence signalling against Fusarium ear blight disease in Arabidopsis

C2 - Non-edited contributions to conferences

Cuzick, A., Urban, M., Maguire, K., Lee, S. and Hammond-Kosack, K. E. 2007. Functional evaluation of plant defence signalling against Fusarium ear blight disease in Arabidopsis. Abstracts BSPP Presidential Meeting 2007: Attack and Defence in Plant Disease, Bath, 12-14 September 2007 . pp. 52

Functional evaluation of plant defence signalling against Fusarium graminearum and F. culmorum in Arabidopsis floral and wheat floral and leaf tissue

C2 - Non-edited contributions to conferences

Hammond-Kosack, K. E., Cuzick, A., Lee, S., Daudi, A., Bass, C. G., Maguire, K. and Urban, M. 2007. Functional evaluation of plant defence signalling against Fusarium graminearum and F. culmorum in Arabidopsis floral and wheat floral and leaf tissue. Abstracts 13th International Congress on Molecular Plant-Microbe Interactions, Sorrento, 21-27 July 2007 . pp. 107-108

The type III pseudomonal exotoxin U activates the c-Jun NH2-terminal kinase pathway and increases human epithelial interleukin-8 production

A - Papers appearing in refereed journals

Cuzick, A., Stirling, F. R., Lindsay, S. L. and Evans, T. J. 2006. The type III pseudomonal exotoxin U activates the c-Jun NH2-terminal kinase pathway and increases human epithelial interleukin-8 production. Infection And Immunity. 74, pp. 4104-4113. https://doi.org/10.1128/IAI.02045-05

Functional evaluation of plant defence signalling against Fusarium ear blight disease in Arabidopsis

C2 - Non-edited contributions to conferences

Cuzick, A., Maguire, K., Lee, S. and Hammond-Kosack, K. E. 2006. Functional evaluation of plant defence signalling against Fusarium ear blight disease in Arabidopsis. Abstracts 17th International Conference on Arabidopsis Research, Madison, 28 June-2 July 2006 .

Segmental duplications and intragenic expansion mould the RPP7 resistance gene cluster

C2 - Non-edited contributions to conferences

Cuzick, A., Wang, X-J., Funderberg, N., Loux, R., Dangl, J., Holub, E. and Mcdowell, J. 2005. Segmental duplications and intragenic expansion mould the RPP7 resistance gene cluster. Abstracts 12th International Congress of Molecular Plant-Microbe Interactions, Cancun, Mexico, 14-18 December 2005 .

Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis

C2 - Non-edited contributions to conferences

Cuzick, A., Lee, S., Urban, M. and Hammond-Kosack, K. E. 2005. Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis. Abstracts LAMP (London Area Molecular Plant Sciences) Meeting, Wye, 5 October 2005 .

Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis

C2 - Non-edited contributions to conferences

Cuzick, A., Lee, S., Urban, M. and Hammond-Kosack, K. E. 2005. Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis. Abstracts 4th Plant Genomics European Meetings (Plant-GEMs 4), Amsterdam, 20-23 September 2005 .

Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis

C2 - Non-edited contributions to conferences

Cuzick, A., Lee, S., Urban, M. and Hammond-Kosack, K. E. 2005. Functional evaluation of plant defence signalling against fusarium ear blight disease in arabidopsis. Abstracts 16th International Conference on Arabidopsis Research, Madison, 15-19 June 2005 . pp. No 530