TPM - Tailoring Plant Metabolism - Work package 2 (WP2) - Designer Willows: high value phenolic glycosides for health and industry
Repository project
| Project dates | 01 Apr 2017 to end of 31 Mar 2022 |
|---|---|
| Researchers | |
| Principal Investigator | Freddie Theodoulou |
| Funder | Biotechnology and Biological Sciences Research Council |
| Project number | I0410 |
| Department | Computational and Analytical Sciences |
| Research fish code | BBS/E/C/000I0410 |
| Grant ID | BBS/E/C/000I0410 |
Outputs
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Targeted and untargeted metabolomics for the evaluation of plant metabolites in response to the environment - editorial
A - Papers appearing in refereed journals
Han, W., Ward, J. L., Kong, Y. and Li, X. 2023. Targeted and untargeted metabolomics for the evaluation of plant metabolites in response to the environment - editorial. Frontiers in Plant Science. 14, p. 1167513. https://doi.org/10.3389/fpls.2023.1167513
Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds
A - Papers appearing in refereed journals
Menard, G. N., Langdon, M., Bhunia, R., Shankhapal, A., Noleto-Dias, C., Lomax, C., Ward, J. L., Kurup, S. and Eastmond, P. J. 2022. Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds. Metabolic Engineering. 70, pp. 196-205. https://doi.org/10.1016/j.ymben.2022.01.016
Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides
A - Papers appearing in refereed journals
Eskandari, H., Ghanadian, M., Noleto-Dias, C., Lomax, C., Tawfike, A., Christiansen, G., Sutherland, D. S., Ward, J. L., Mohammad-Beigi, H. and Otzen, D. E. 2020. Inhibitors of α-Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides. ACS Chemical Neuroscience. 11 (19), pp. 3161-3173. https://doi.org/10.1021/acschemneuro.0c00528
A willow UDP-glycosyltransferase involved in salicinoid biosynthesis
A - Papers appearing in refereed journals
Kulasekaran, S., Cerezo-Medina, S., Harflett, C., Lomax, C., DeJong, F., Rendour, A., Ruvo, G., Hanley, S. J., Beale, M. H. and Ward, J. L. 2020. A willow UDP-glycosyltransferase involved in salicinoid biosynthesis. Journal of Experimental Botany. 72 (5), p. 1634–1648. https://doi.org/10.1093/jxb/eraa562
Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy.
A - Papers appearing in refereed journals
Ward, J. L., Wu, Y., Harflett, C., Onafuye, H., Corol, D. I., Lomax, C., Macalpine, W. J., Cinatl, J., Wass, M. N., Michaelis, M. and Beale, M. H. 2020. Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy. Scientific Reports. 10, p. 6477. https://doi.org/10.1038/s41598-020-63349-1
Sulfated flavanones and dihydroflavonols from willow
A - Papers appearing in refereed journals
Noleto-Dias, C., Harflett, C., Beale, M. H. and Ward, J. L. 2020. Sulfated flavanones and dihydroflavonols from willow. Phytochemistry Letters. 35 (February), pp. 88-93. https://doi.org/10.1016/j.phytol.2019.11.008
Phenylalkanoid glycosides (non-salicinoids) from wood chips of Salix triandra × dasyclados hybrid willow
A - Papers appearing in refereed journals
Noleto-Dias, C., Wu, Y., Bellisai, A., Macalpine, W. J., Beale, M. H. and Ward, J. L. 2019. Phenylalkanoid glycosides (non-salicinoids) from wood chips of Salix triandra × dasyclados hybrid willow. Molecules. 24 (6), p. 1152. https://doi.org/10.3390/molecules24061152
A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants
A - Papers appearing in refereed journals
Mohammed-Beigi, H., Kjaer, L., Eskandari, H., Aliakbari, F., Christiansen, G., Ruvo, G., Ward, J. L. and Otzen, D.E. 2019. A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants. Frontiers in Plant Science. 10, p. 148. https://doi.org/10.3389/fpls.2019.00148
Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
A - Papers appearing in refereed journals
Mohammed-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A., Shafer, N.P., Amiri-Nowdijeh, A., Eskandari, E., Moller, I.M., Hosseini-Mazinani, M., Christiansen, G., Ward, J. L., Morshedi, D. and Otzen, D.E 2019. Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. Journal of Biological Chemistry. 294, pp. 4215-4232. https://doi.org/10.1074/jbc.RA118.005723
Genomic index selection provides a pragmatic framework for setting and refining multi-objective breeding targets in Miscanthus
A - Papers appearing in refereed journals
Slavov, G. T., Davey, C. L., Bosch, M., Robson, P. R. H., Donnison, I. S. and MacKay, I. J. 2018. Genomic index selection provides a pragmatic framework for setting and refining multi-objective breeding targets in Miscanthus. Annals of Botany. pp. 1-9. https://doi.org/10.1093/aob/mcy187
Breeding progress and preparedness for mass-scale deployment of perennial lignocellulosic biomass crops switchgrass, miscanthus, willow, and poplar
A - Papers appearing in refereed journals
Clifton-Brown, J., Harfouche, A., Casler, M. D., Jones, H. D., Macalpine, W. J., Murphy-Bokern, D., Smart, L. B., Adler, A., Ashman, C., Awty-Carroll, D., Bastien, C., Bopper, S., Botnari, V., Brancourt-Hulmel, M., Chen, Z., Clark, L. V., Cosentino, S., Dalton, S., Davey, C., Dolstra, O., Donnison, I., Flavell, R., Greef, J., Hanley, S. J., Hastings, A., Hertzberg, M., Hsu, T., Huang, L., Iurato, A., Jensen, E., Jin, X., Jørgensen, U., Kiesel, A., Kim, D., Liu, J., McCalmont, J. P., McMahon, B. G., Mos, M., Robson, P., Sacks, E. J., Sandu, A., Scalici, G., Schwarz, K., Scordia, D., Shafiei, R., Shield, I. F., Slavov, G., Stanton, B. J., Swaminathan, K., Taylor, G., Torres, A. F., Trindade, L. M., Tschaplinski, T., Tuskan, J., Yamada, T., Yu, C. Y., Zalesny, R., Zong, J. and Lewandowski, I. 2018. Breeding progress and preparedness for mass-scale deployment of perennial lignocellulosic biomass crops switchgrass, miscanthus, willow, and poplar. Global Change Biology. Bioenergy. https://doi.org/10.1111/gcbb.12566
Species and Genotype Effects of Bioenergy Crops on Root Production, Carbon and Nitrogen in Temperate Agricultural Soil
A - Papers appearing in refereed journals
Gregory, A. S., Dungait, J. A. J., Shield, I. F., Macalpine, W. J., Cunniff, J., Durenkamp, M., White, R. P., Joynes, A. and Richter, G. M. 2018. Species and Genotype Effects of Bioenergy Crops on Root Production, Carbon and Nitrogen in Temperate Agricultural Soil. BioEnergy Research. 11 (2), pp. 382-397. https://doi.org/10.1007/s12155-018-9903-6
Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine
A - Papers appearing in refereed journals
Noleto-Dias, C., Ward, J. L., Bellisai, A., Lomax, C. and Beale, M. H. 2018. Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine. Fitoterapia. 127 (June), pp. 166-172. https://doi.org/10.1016/j.fitote.2018.02.009