Guillaume Menard

NameGuillaume Menard
Job titleMetabolic Engineer
Email addressguillaume.menard@rothamsted.ac.uk
DepartmentPlant Sciences and the Bioeconomy
Research clusterPS: Oilseed Metabolism and Development
Preferred citationMenard, G. N.
OfficeHarpenden

Research outputs

Burden tests can be used to map causal genes for a simple metabolic trait in an exome-sequenced polyploid mutant population

Menard, G. N. and Eastmond, P. J. 2022. Burden tests can be used to map causal genes for a simple metabolic trait in an exome-sequenced polyploid mutant population. Plant Biotechnology Journal. https://doi.org/10.1111/pbi.13890

A native promoter–gene fusion created by CRISPR/Cas9-mediated genomic deletion offers a transgene-free method to drive oil accumulation in leaves

Bhunia, R. K., Menard, G. N. and Eastmond, P. J. 2022. A native promoter–gene fusion created by CRISPR/Cas9-mediated genomic deletion offers a transgene-free method to drive oil accumulation in leaves. FEBS Letters. https://doi.org/10.1002/1873-3468.14365

Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds

Menard, G. N., Langdon, M., Bhunia, R., Shankhapal, A., Noleto-Dias, C., Lomax, C., Ward, J. L., Kurup, S. and Eastmond, P. J. 2022. Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds. Metabolic Engineering. 70, pp. 196-205. https://doi.org/10.1016/j.ymben.2022.01.016

Production of human milk fat substitute by engineered strains of Yarrowia lipolytica

Bhutada, G., Menard, G. N., Bhunia, R. K., Hapeta, P. P., Ledesma-Amaro, R. and Eastmond, P. J. 2022. Production of human milk fat substitute by engineered strains of Yarrowia lipolytica. Metabolic Engineering Communications. 14 (June), p. e00192. https://doi.org/10.1016/j.mec.2022.e00192

Laboratory phenomics predicts field performance and identifies superior indica haplotypes for early seedling vigour in dry direct-seeded rice

Menard, G. N., Sandhu, N., Anderson, D., Catolos, M., Hassall, K. L., Eastmond, P. J., Kumar, A. and Kurup, S. 2021. Laboratory phenomics predicts field performance and identifies superior indica haplotypes for early seedling vigour in dry direct-seeded rice. Genomics. 113 (6), pp. 4227-4236. https://doi.org/10.1016/j.ygeno.2021.11.006

Natural variation in acyl editing is a determinant of seed storage oil composition

Menard, G. N., Bryant, F. M., Kelly, A. A., Craddock, C. P., Lavagi, I., Hassani-Pak, K., Kurup, S. and Eastmond, P. J. 2018. Natural variation in acyl editing is a determinant of seed storage oil composition. Scientific Reports. 8, p. 17346. https://doi.org/10.1038/s41598-018-35136-6

Engineering of tomato for the sustainable production of ketocarotenoids and its evaluation in aquaculture feed

Nogueira, M., Enfissi, E. M. A., Martínez Valenzuela, M. E., Menard, G. N., Driller, R. L., Eastmond, P. J., Schuch, W., Sandmann, G. and Fraser, P. D. 2017. Engineering of tomato for the sustainable production of ketocarotenoids and its evaluation in aquaculture feed. Proceedings of the National Academy of Sciences. 114 (41), pp. 10876-10881. https://doi.org/10.1073/pnas.1708349114

Fatty acids in arbuscular mycorrhizal fungi are synthesized by the host plant

Luginbuehl, L. H., Menard, G. N., Kurup, S., Van-Erp, H., Radhakrishnan, G. V., Breakspear, A., Oldroyd, G. E. D. and Eastmond, P. J. 2017. Fatty acids in arbuscular mycorrhizal fungi are synthesized by the host plant. Science - AAAS. 356 (6343), pp. 1175-1178. https://doi.org/10.1126/science.aan0081

Genome wide analysis of fatty acid desaturation and its response to temperature

Menard, G. N., Martin-Moreno, J., Bryant, F. M., Munoz-Azcarate, O., Kelly, A. A., Hassani-Pak, K., Kurup, S. and Eastmond, P. J. 2017. Genome wide analysis of fatty acid desaturation and its response to temperature. Plant Physiology. 173 (3), pp. 1594-1605. https://doi.org/10.1104/pp.16.01907

Arabidopsis uses two gluconeogenic gateways for organic acids to fuel seedling establishment

Eastmond, P. J., Astley, H. M., Parsley, K., Aubry, S., Williams, B. P., Menard, G. N., Craddock, C. P., Nunes-Nesi, A., Fernie, A. R. and Hibberd, J. M. 2015. Arabidopsis uses two gluconeogenic gateways for organic acids to fuel seedling establishment. Nature Communications. 6, p. 6659. https://doi.org/10.1038/ncomms7659

Multigene engineering of triacylglycerol metabolism boosts seed oil content in Arabidopsis

Van-Erp, H., Kelly, A. A., Menard, G. N. and Eastmond, P. J. 2014. Multigene engineering of triacylglycerol metabolism boosts seed oil content in Arabidopsis. Plant Physiology. 165, pp. 30-36. https://doi.org/10.1104/pp.114.236430

The SUGAR-DEPENDENT1 lipase limits triacyglycerol accumulation in vegetative tissues of Arabidopsis

Kelly, A. A., Van-Erp, H., Quettier, A-L., Shaw, E., Menard, G. N., Kurup, S. and Eastmond, P. J. 2013. The SUGAR-DEPENDENT1 lipase limits triacyglycerol accumulation in vegetative tissues of Arabidopsis. Plant Physiology. 162, pp. 1282-1289. https://doi.org/10.1104/pp.113.219840

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