Computational and Analytical Sciences

TitleComputational and Analytical Sciences
TypeScience Department
InstituteRothamsted Research
HeadChris Rawlings
Executive AssistantSally Murdoch

Outputs

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Functional QTL mapping and genomic prediction of canopy height in wheat measured using a robotic field phenotyping platform

A - Papers appearing in refereed journals
Lyra, D. H., Virlet, N., Sadeghi-Tehran, P., Hassall, K. L., Wingen, L. U., Orford, S., Griffiths, S., Hawkesford, M. J. and Slavov, G. 2020. Functional QTL mapping and genomic prediction of canopy height in wheat measured using a robotic field phenotyping platform . Journal of Experimental Botany. p. erz545. https://doi.org/10.1093/jxb/erz545

Population genetic structure and predominance of cyclical parthenogenesis in the bird cherry–oat aphid Rhopalosiphum padi in England

A - Papers appearing in refereed journals
Morales-Hojas, R., Gonzalez-Uriarte, A., Alvira-Iraizoz, F., Jenkins, T., Alderson, L. J., Kruger, T., Hall, M. J., Greenslade, A. F. C., Shortall, C. R. and Bell, J. R. 2020. Population genetic structure and predominance of cyclical parthenogenesis in the bird cherry–oat aphid Rhopalosiphum padi in England. Evolutionary Applications. https://doi.org/10.1111/eva.12917

Linking small-scale flight manoeuvers and density profiles to the vertical movement of insects in the nocturnal stable boundary layer

A - Papers appearing in refereed journals
Wainwright, C. E., Reynolds, D. R. and Reynolds, A. M. 2020. Linking small-scale flight manoeuvers and density profiles to the vertical movement of insects in the nocturnal stable boundary layer. Scientific Reports. 10, p. 1019. https://doi.org/10.1038/s41598-020-57779-0

Soil organic carbon, extracellular polymeric substances (EPS), and soil structural stability as affected by previous and current land-use

A - Papers appearing in refereed journals
Redmile-Gordon, M. A., Watts, C. W., Gregory, A. S. and White, R. P. 2020. Soil organic carbon, extracellular polymeric substances (EPS), and soil structural stability as affected by previous and current land-use. Geoderma. 363 (1st April), p. 114143. https://doi.org/10.1016/j.geoderma.2019.114143

Epigenetic patterns within the haplotype phased fig (Ficus carica L.) genome

A - Papers appearing in refereed journals
Usai, G., Mascagni, F., Giordani, T., Vangelisti, A., Bose, E., Zuccolo, A., Ceccarelli, M., King, R., Hassani-Pak, K., Zambrano, L. S., Cavallini, A. and Natali, L. 2020. Epigenetic patterns within the haplotype phased fig (Ficus carica L.) genome. The Plant Journal. https://doi.org/10.1111/tpj.14635

Additive and heterozygous (dis)advantage GWAS models reveal candidate genes involved in the genotypic variation of maize hybrids to Azospirillum brasilense

A - Papers appearing in refereed journals
Vidotti, M. S., Lyra, D. H., Morosini, J. S., Granato, I. S. C., Quecine, M. C., Azevedo, J. L. and Fritsche-Neto, R. 2019. Additive and heterozygous (dis)advantage GWAS models reveal candidate genes involved in the genotypic variation of maize hybrids to Azospirillum brasilense . PLOS ONE. 14 (9), p. e0222788. https://doi.org/10.1371/journal.pone.0222788

Foliar N Application at Anthesis Stimulates Gene Expression of Grain Protein Fractions and Alters Protein Body Distribution in Winter Wheat (Triticum aestivum L.)

A - Papers appearing in refereed journals
Rossmann, A., Buchner, P. H., Savill, G. P., Powers, S. J., Hawkesford, M. J. and Muhling, K. H. 2019. Foliar N Application at Anthesis Stimulates Gene Expression of Grain Protein Fractions and Alters Protein Body Distribution in Winter Wheat (Triticum aestivum L.) . Journal of Agricultural and Food Chemistry - JAFC. 67 (46), pp. 12709-12719. https://doi.org/10.1021/acs.jafc.9b04634

Genetic structure at national and regional scale in a long-distance dispersing pest organism, the bird cherry–oat aphid Rhopalosiphum padi

A - Papers appearing in refereed journals
Morales-Hojas, R., Gonzalez-Uriarte, A., Alvira-Iraizoz, F., Jenkins, T., Alderson, L. J., Kruger, T., Hall, M. J., Greenslade, A. F. C., Shortall, C. R. and Bell, J. R. 2019. Genetic structure at national and regional scale in a long-distance dispersing pest organism, the bird cherry–oat aphid Rhopalosiphum padi. bioRxiv. https://doi.org/10.1101/829986

Investigating vertical motion of small insects in the atmospheric boundary layer using millimetre-wavelength radar and Doppler LIDAR

Conference paper
Wainwright, C. E., Stepanian, P. M., Reynolds, D. R. and Reynolds, A. M. 2019. Investigating vertical motion of small insects in the atmospheric boundary layer using millimetre-wavelength radar and Doppler LIDAR. Institution of Engineering and Technology. https://doi.org/10.1049/joe.2019.0596

Transcriptome sequencing, molecular markers, and transcription factor discovery of Platanus acerifolia in the presence of Corythucha ciliata

A - Papers appearing in refereed journals
Li, F., Wu, C., Gao, M., Jiao, M., Qu, C., Gonzalez-Uriarte, A. and Luo, C. 2019. Transcriptome sequencing, molecular markers, and transcription factor discovery of Platanus acerifolia in the presence of Corythucha ciliata. Scientific Data. 6 (128). https://doi.org/10.1038/s41597-019-0111-9

Metabolomics analysis and biological investigation of three Malvaceae plants

A - Papers appearing in refereed journals
Abdelhafez, O. H., Othman, E. M., Fahim, J. R., Desoukey, S. Y., Pimentel-Elardo, S. M., Nodwell, J. R., Schirmeister, T., Tawfike, A. and Adbelmohsen, U. R. 2019. Metabolomics analysis and biological investigation of three Malvaceae plants. Phytochemical Analysis. https://doi.org/10.1002/pca.2883

Mass Seasonal Migrations of Hoverflies Provide Extensive Pollination and Crop Protection Services

A - Papers appearing in refereed journals
Wotton, K. R., Gao, B., Menz, M. H. M., Morris, R. K. A., Ball, S. G., Lim, K. S., Reynolds, D. R., Hu, G. and Chapman, J. W. 2019. Mass Seasonal Migrations of Hoverflies Provide Extensive Pollination and Crop Protection Services. Current Biology. 29 (13), pp. 2167-2173.e5. https://doi.org/10.1016/j.cub.2019.05.036

Contrasting gene expression patterns in grain of high and low asparagine wheat genotypes in response to sulphur supply

A - Papers appearing in refereed journals
Curtis, T., Raffan, S., Wan, Y., King, R., Gonzalez-Uriarte, A. and Halford, N. G. 2019. Contrasting gene expression patterns in grain of high and low asparagine wheat genotypes in response to sulphur supply. BMC Genomics. 20, p. 628. https://doi.org/10.1186/s12864-019-5991-8

Screening of locally available organic materials as substrates for production of Pochonia chlamydosporia in Kenya

A - Papers appearing in refereed journals
Luambano, N, Manzanilla-Lopez, R. H. and Powers, S. J. 2019. Screening of locally available organic materials as substrates for production of Pochonia chlamydosporia in Kenya. Biological Control. 133, pp. 18-25. https://doi.org/10.1016/j.biocontrol.2019.03.001

Molecular quantification of Plasmodium parasite density from the blood retained in used RDTs

A - Papers appearing in refereed journals
Robinson, A., Busula, A., Muwanguzi, J., Powers, S. J., Masiga, D., Bousema, T., Takken, W., de Boer, J., Logan, J., Beshir, K. and Sutherland, C. 2019. Molecular quantification of Plasmodium parasite density from the blood retained in used RDTs. Scientific Reports. 9 (5107). https://doi.org/10.1038/s41598-019-41438-0

Bayesian analysis and prediction of hybrid performance

A - Papers appearing in refereed journals
Alves, F. C., Granato, I. S. C., Galli, g, Lyra, D. H., Fritsche-Neto, R. and De los Campos, G. 2019. Bayesian analysis and prediction of hybrid performance. Plant Methods. 15, p. 14. https://doi.org/10.1186/s13007-019-0388-x

Modeling copy number variation in the genomic prediction of maize hybrids

A - Papers appearing in refereed journals
Lyra, D. H., Galli, G., Alves, F. C., Granato, I. S. C., Vidotti, M. S., Sousa, M. B., Morosini, J. S., Crossa, J. and Fritsche-Neto, R. 2019. Modeling copy number variation in the genomic prediction of maize hybrids. Theoretical and Applied Genetics. 132, pp. 273-288. https://doi.org/10.1007/s00122-018-3215-2

Influence of Pickling Process on Allium cepa and Citrus limon Metabolome as Determined via Mass Spectrometry-Based Metabolomics

A - Papers appearing in refereed journals
Tawfike, A. F., Farag, M. A., Donia, M. S., Ehrlich, A. and Wessjohann, L. A. 2019. Influence of Pickling Process on Allium cepa and Citrus limon Metabolome as Determined via Mass Spectrometry-Based Metabolomics. Molecules. 24 (5), p. 928. https://doi.org/10.3390/molecules24050928

Identification of a non-host semiochemical from tick-resistant donkeys (Equus asinus) against Amblyomma sculptum ticks

A - Papers appearing in refereed journals
Ferreira, L. L., Sarria, A. L. F., De Olivera Filho, J. G., De Olivera de Silva, F., Powers, S. J., Caulfield, J. C., Pickett, J. A., Birkett, M. A. and Borges, L. M. F. 2019. Identification of a non-host semiochemical from tick-resistant donkeys (Equus asinus) against Amblyomma sculptum ticks. Ticks and Tick-Borne Diseases. 10 (3), pp. 621-627. https://doi.org/10.1016/j.ttbdis.2019.02.006

Application of metabolomics and molecular networking in investigating the chemical profile and antitrypanosomal activity of British bluebells ( Hyacinthoides non-scripta )

A - Papers appearing in refereed journals
Raheem, D., Tawfike, A. F, Abdulmohsen, U., Edrada-Ebel, R. and Fitzsimmons-Thoss, V. 2019. Application of metabolomics and molecular networking in investigating the chemical profile and antitrypanosomal activity of British bluebells ( Hyacinthoides non-scripta ). Scientific Reports. 9 (1), p. 2547. https://doi.org/10.1038/s41598-019-38940-w

Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

A - Papers appearing in refereed journals
Mohammed-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A., Shafer, N.P., Amiri-Nowdijeh, A., Eskandari, E., Moller, I.M., Hosseini-Mazinani, M., Christiansen, G., Ward, J. L., Morshedi, D. and Otzen, D.E 2019. Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. Journal of Biological Chemistry. 294, pp. 4215-4232. https://doi.org/10.1074/jbc.RA118.005723

New bioactive metabolites from the elicited marine sponge-derived bacterium Actinokineospora spheciospongiae sp. nov.

A - Papers appearing in refereed journals
Tawfike, A., Attia, E. Z., Desoukey, S. Y., Hajjar, D., Makki, A. A., Schupp, P. J., Edrada-Ebel, R. and Abdelmohsen, U. R. 2019. New bioactive metabolites from the elicited marine sponge-derived bacterium Actinokineospora spheciospongiae sp. nov. AMB Express. 9 (12). https://doi.org/10.1186/s13568-018-0730-0

Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics

A - Papers appearing in refereed journals
Tawfike, A. F, Romli, M., Clements, C., Abbott, G., Young, L., Schumacher, M., Diederich, M., Farag, M. and Edrada-Ebel, R. 2019. Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics. Journal Of Chromatography B. 1106-1107 (1 February), pp. 71-83. https://doi.org/10.1016/j.jchromb.2018.12.032

Determination of the prebiotic activity of wheat arabinogalactan peptide (AGP) using batch culture fermentation

A - Papers appearing in refereed journals
Harris, S., Powers, S. J., Monteagudo-Mera, A., Kosik, O., Lovegrove, A., Shewry, P. R. and Charalampopoulos, D. 2019. Determination of the prebiotic activity of wheat arabinogalactan peptide (AGP) using batch culture fermentation. European Journal Of Nutrition. https://doi.org/10.1007/s00394-019-01908-7

4 Per Mille – Is It Feasible to sequester

C2 - Non-edited contributions to conferences
Powlson, D. S., Poulton, P. R., Macdonald, A. J., Johnston, A. E., White, R. P. and Goulding, K. W. T. 2018. 4 Per Mille – Is It Feasible to sequester .

Migratory Insect Multifrequency Radar Cross Sections for Morphological Parameter Estimation

A - Papers appearing in refereed journals
Wang, R., Hu, C., Liu, C., Long, T., Kong, S., Lang, T., Gould, P. J. L., Lim, J. and Wu, K. 2018. Migratory Insect Multifrequency Radar Cross Sections for Morphological Parameter Estimation. IEEE Transactions on Geoscience and Remote Sensing. 57 (6), pp. 3450-3461. https://doi.org/10.1109/TGRS.2018.2884926

Controlling population structure in the genomic prediction of tropical maize hybrids

A - Papers appearing in refereed journals
Lyra, D. H., Granato, Morais, P. P. P., Alves, F. C., Santos, A. R. M., Yu, X., Guo, T., Yu, J. and Fritsche-Neto, R. 2018. Controlling population structure in the genomic prediction of tropical maize hybrids. Molecular Breeding. 38 (126). https://doi.org/10.1007/s11032-018-0882-2

Metabolomic-Guided Isolation of Bioactive Natural Products from Curvularia sp., an Endophytic Fungus of Terminalia laxiflora

A - Papers appearing in refereed journals
Tawfike, A. F., Abbott, G., Young, L. and Edrada-Ebel, R. 2018. Metabolomic-Guided Isolation of Bioactive Natural Products from Curvularia sp., an Endophytic Fungus of Terminalia laxiflora. Planta Medica. 84 (3), pp. 182-190. https://doi.org/10.1055/s-0043-118807

Final grain weight is not limited by the activity of key starch-synthesising enzymes during grain filling in wheat

A - Papers appearing in refereed journals
Fahy, B., Siddiqui, H., David, L., Powers, S. J., Borrill, P., Uauy, C. and Smith, A. 2018. Final grain weight is not limited by the activity of key starch-synthesising enzymes during grain filling in wheat. Journal of Experimental Botany. 69 (22), p. 5461–5475. https://doi.org/10.1093/jxb/ery314

Occurrence of Puccinia spp. spores in Madeira Island and their phytopathological importance

A - Papers appearing in refereed journals
Camacho, I., Leça, R., Sardinha, D., Camacho, R. and Sadys, M. 2018. Occurrence of Puccinia spp. spores in Madeira Island and their phytopathological importance. European Journal of Plant Pathology. 150 (4), pp. 955-969. https://doi.org/10.1007/s10658-017-1335-1

Dew point temperature affects ascospore release of allergenic genus Leptosphaeria

A - Papers appearing in refereed journals
Sadys, M., Kaczmarek, J., Grinn-Gofron, A., Rodinkova, V., Prikhodko, A., Bilous, E., Strzelczak, A., Herbert, R. J. and Jedryczka, M. 2018. Dew point temperature affects ascospore release of allergenic genus Leptosphaeria. International Journal Of Biometeorology. 62 (6), pp. 979-990. https://doi.org/10.1007/s00484-018-1500-z

Dry matter losses and quality changes during short rotation coppice willow storage in chip or rod form

A - Papers appearing in refereed journals
Whittaker, C., Yates, N. E., Powers, S. J., Misselbrook, T. H. and Shield, I. F. 2018. Dry matter losses and quality changes during short rotation coppice willow storage in chip or rod form. Biomass & Bioenergy. 112, pp. 29-36. https://doi.org/10.1016/j.biombioe.2018.02.005

The tethered flight technique as a tool for studying life‐history strategies associated with migration in insects

A - Papers appearing in refereed journals
Minter, M., Pearson, A. J., Lim, K. S., Wilson, K., Chapman, J. W. and Jones, C. M. 2018. The tethered flight technique as a tool for studying life‐history strategies associated with migration in insects. Ecological Entomology. 43 (4). https://doi.org/10.1111/een.12521

Ongoing changes in migration phenology and winter residency at Bracken Bat Cave

A - Papers appearing in refereed journals
Stepanian, P. M. and Wainwright, C. E. 2018. Ongoing changes in migration phenology and winter residency at Bracken Bat Cave. Global Change Biology. 24 (7), pp. 3266-3275. https://doi.org/10.1111/gcb.14051

Effects of variety, year of cultivation and sulphur supply on the accumulation of free asparagine in the grain of commercial wheat varieties

A - Papers appearing in refereed journals
Curtis, T., Powers, S. J., Wang, R. and Halford, N. G. 2018. Effects of variety, year of cultivation and sulphur supply on the accumulation of free asparagine in the grain of commercial wheat varieties. Food Chemistry. 239 (15 January), pp. 304-313. https://doi.org/10.1016/j.foodchem.2017.06.113

Host shift induces changes in mate choice of the seed predator Acanthoscelides obtectus via altered chemical signalling

A - Papers appearing in refereed journals
Vuts, J., Woodcock, C. M., Koenig, L., Powers, S. J., Pickett, J. A., Szentesi, A. and Birkett, M. A. 2018. Host shift induces changes in mate choice of the seed predator Acanthoscelides obtectus via altered chemical signalling. PLOS ONE. 13 (11), p. e0206144. https://doi.org/10.1371/journal.pone.0206144

KnetMaps: a BioJS component to visualize biological knowledge networks

A - Papers appearing in refereed journals
Singh, A., Rawlings, C. J. and Hassani-Pak, K. 2018. KnetMaps: a BioJS component to visualize biological knowledge networks. F1000Research. 7, p. 1651. https://doi.org/10.12688/f1000research.16605.1

4 per mille – is it feasible to sequester soil carbon at this rate annually in agricultural soils?

C2 - Non-edited contributions to conferences
Powlson, D. S., Poulton, P. R., Macdonald, A. J., Johnston, A. E., White, R. P. and Goulding, K. W. T. 2018. 4 per mille – is it feasible to sequester soil carbon at this rate annually in agricultural soils?

Impact of Phenotypic Correction Method and Missing Phenotypic Data on Genomic Prediction of Maize Hybrids

A - Papers appearing in refereed journals
Galli, G, Lyra, D. H., Alves, F. C, Granato, I. S. C., Bandeira-Sousa, M. and Fritsche-Neto, R 2018. Impact of Phenotypic Correction Method and Missing Phenotypic Data on Genomic Prediction of Maize Hybrids. Crop Science. 58 (4), pp. 1481-1491. https://doi.org/10.2135/cropsci2017.07.0459

Characterizing animal anatomy and internal composition for electromagnetic modelling in radar entomology

A - Papers appearing in refereed journals
Mirkovic, D., Stepanian, P. M., Wainwright, C. E., Reynolds, D. R. and Menz, M. H. M. 2018. Characterizing animal anatomy and internal composition for electromagnetic modelling in radar entomology. Remote Sensing in Ecology and Conservation. https://doi.org/10.1002/rse2.94

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