Optimal weighting of information in marker-assisted selection

A - Papers appearing in refereed journals

Whittaker, J. C., Haley, C. S. and Thompson, R. 1997. Optimal weighting of information in marker-assisted selection. Genetics Research. 69 (2), pp. 137-144.

AuthorsWhittaker, J. C., Haley, C. S. and Thompson, R.

In crosses between inbred lines linear regression can be used to estimate marker effects; these marker effects then allow marker-assisted selection (MAS) for quantitative traits. Weighting of marker and phenotypic information in MAS requires estimation of genetic variance associated with the markers: the usual estimators are biased, resulting in too much weight being placed on marker information relative to phenotypic information. In this paper we develop a cross-validation method to remove this bias, and show by simulation that response to selection using this method is almost as high as that achieved using optimal weighting of marker and phenotypic information.

Year of Publication1997
JournalGenetics Research
Journal citation69 (2), pp. 137-144
Digital Object Identifier (DOI)doi:10.1017/S0016672397002711
Open accessPublished as non-open access
Funder project or code207
Project: 141673
Output statusPublished
Publication dates
Print01 Apr 1997
Publication process dates
Accepted20 Jan 1997
Copyright licensePublisher copyright
PublisherCambridge University Press (CUP)

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