PS: Lipid Metabolic Engineering and Synthetic Biology

TitlePS: Lipid Metabolic Engineering and Synthetic Biology
TypeResearch cluster

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Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent CA 2476041 A1)

H2 - Patents applied for
Napier, J. A. and Sayanova, O. V. 2003. Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent CA 2476041 A1). CA 2476041 A1

Delta 6-desaturases From Primulaceae (Patent GB 2385852 A)

H2 - Patents applied for
Napier, J. A. and Sayanova, O. V. 2003. Delta 6-desaturases From Primulaceae (Patent GB 2385852 A) . GB 2385852 A

Desaturase (Patent US 2003/0152983 A1)

H2 - Patents applied for
Napier, J. A., Michaelson, L. V. and Stobart, K. 2003. Desaturase (Patent US 2003/0152983 A1). US 2003/0152983 A1

Semiochemical (Patent US 2003/0109586 A1)

H2 - Patents applied for
Pickett, J. A., Wadhams, L. J., Hick, A. J. and Napier, J. A. 2003. Semiochemical (Patent US 2003/0109586 A1). US 2003/0109586 A1

Physiological responses of the CAM epiphyte Tillandsia usneoides L. (Bromeliaceae) to variations in light and water supply

A - Papers appearing in refereed journals
Haslam, R. P., Borland, A., Maxwell, K. and Griffiths, H. 2003. Physiological responses of the CAM epiphyte Tillandsia usneoides L. (Bromeliaceae) to variations in light and water supply. Journal of Plant Physiology. 160, pp. 627-634.

Molecular analysis of "stay green" mutants in durum wheat

C2 - Non-edited contributions to conferences
Rampino, P., Spano, G., Trono, D., Di Fonzo, N., Shewry, P. R., Napier, J. A. and Perrotta, C. 2003. Molecular analysis of "stay green" mutants in durum wheat. Proceedings 10th International Wheat Genetics Symposium, Paestum, Italy, 1-6 September 2003. Vol. 2 - Poster Presentations . pp. 905-907

Production of high value chemicals in plants

B - Book chapters etc edited externally
Beale, M. H. and Napier, J. A. 2003. Production of high value chemicals in plants. in: Shewry, P. R., Lenton, J. R. and Anderson, H. M. (ed.) Long Ashton Research Station: one hundred years of science in support of agriculture Institute for Arable Crops Research (IACR) , Long Ashton Research Station (LARS), Bristol. pp. 284-290

Expression of the gamma-zein protein of maize in seeds of transgenic barley: effects on grain composition and properties

A - Papers appearing in refereed journals
Zhang, Y., Darlington, H., Jones, H. D., Halford, N. G., Napier, J. A., Davey, M. R., Lazzeri, P. A. and Shewry, P. R. 2003. Expression of the gamma-zein protein of maize in seeds of transgenic barley: effects on grain composition and properties. Theoretical and Applied Genetics. 106 (6), pp. 1139-1146. https://doi.org/10.1007/s00122-002-1162-3

TaqMan PCR for detection of genetically modified durum wheat

A - Papers appearing in refereed journals
Terzi, V., Ferrari, B., Finocchiaro, F., Di Fonzo, N., Stanca, A. M., Lamacchia, C., Napier, J. A., Shewry, P. R. and Faccioli, P. 2003. TaqMan PCR for detection of genetically modified durum wheat. Journal of Cereal Science. 37, pp. 157-163.

Identification of Primula fatty acid delta6-desaturases with n-3 substrate preferences

A - Papers appearing in refereed journals
Sayanova, O. V., Beaudoin, F., Michaelson, L. V., Shewry, P. R. and Napier, J. A. 2003. Identification of Primula fatty acid delta6-desaturases with n-3 substrate preferences. FEBS Letters. 542 (1-3), pp. 100-104. https://doi.org/10.1016/S0014-5793(03)00358-2

The role of cytochrome b 5 fusion desaturases in the synthesis of polyunsaturated fatty acids

A - Papers appearing in refereed journals
Napier, J. A., Michaelson, L. V. and Sayanova, O. V. 2003. The role of cytochrome b 5 fusion desaturases in the synthesis of polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids. 68 (2), pp. 135-143. https://doi.org/10.1016/S0952-3278(02)00263-6

The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe

A - Papers appearing in refereed journals
Garton, S., Michaelson, L. V., Beaudoin, F., Beale, M. H. and Napier, J. A. 2003. The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe. FEBS Letters. 538, pp. 192-196.

Characterisation of the glutathione-dependent formaldehyde detoxification pathway in Arabidopsis, wheat and rice

C2 - Non-edited contributions to conferences
Haslam, R. P., Downie, A. L., John, P., Parry, M. A. J., Cole, D., Pallett, K. and Coleman, J. O. D. 2003. Characterisation of the glutathione-dependent formaldehyde detoxification pathway in Arabidopsis, wheat and rice. Society for Experimental Biology Annual Main Meeting: 31st March–4th April 2002, Southampton, UK  . https://doi.org/10.1016/S1095-6433(03)00034-5

A focus on the fascinating world of one-carbon metabolism

C2 - Non-edited contributions to conferences
Downie, A. L., Haslam, R. P., John, P., Parry, M. A. J., Cole, D., Pallett, K. and Coleman, J. O. D. 2003. A focus on the fascinating world of one-carbon metabolism. Society for Experimental Biology Annual Main Meeting: 31st March–4th April 2002, Southampton, UK . https://doi.org/10.1016/S1095-6433(03)00034-5

New lipid-derived signals in plants and their role in modulating gene expression

C2 - Non-edited contributions to conferences
Matthes, M. C., Michaelson, L. V., Beaudoin, F., Garton, S., Pickett, J. A. and Napier, J. A. 2003. New lipid-derived signals in plants and their role in modulating gene expression.

Global expression profiling of the response of chemically regulated genes in Arabidopsis

C2 - Non-edited contributions to conferences
Downie, A. L., Haslam, R. P., Miyazaki, S., Bohnert, H. J., John, P., Parry, M. A. J. and Coleman, J. O. D. 2003. Global expression profiling of the response of chemically regulated genes in Arabidopsis. Abstracts COST 837 Achievement and Prospects of Phytoremediation in Europe: Final Scientific Workshop and Management Committee Meeting, Vienna, 15-18 October 2003 .

Global expression profiling of the response of chemically regulated genes in Arabidopsis

C2 - Non-edited contributions to conferences
Haslam, R. P., Downie, A. L., Miyazaki, S., Bohnert, H. J., John, P., Coleman, J. O. D. and Parry, M. A. J. 2003. Global expression profiling of the response of chemically regulated genes in Arabidopsis. Abstracts ASPB Annual Meeting Plant Biology 2003, Honolulu, 25-30 July 2003 . pp. Abs 1358

An assessment of enriched apoplastic extracts by proteomic analysis

C2 - Non-edited contributions to conferences
Haslam, R. P., Downie, A. L., Raveton, M., Gallardo, K., Job, D., Pallett, K. E., John, P., Parry, M. A. J. and Coleman, J. O. D. 2003. An assessment of enriched apoplastic extracts by proteomic analysis. Abstracts COST 837 Achievement and Prospects of Phytoremediation in Europe: Final Scientific Workshop and Management Committee Meeting, Vienna, 15-18 October 2003 .

The assessment of enriched apoplastic extracts using proteomic approaches

A - Papers appearing in refereed journals
Haslam, R. P., Downie, A. J., Raveton, M., Gallardo, K., Job, D., Pallett, K. E., John, P., Parry, M. A. J. and Coleman, J. O. D. 2003. The assessment of enriched apoplastic extracts using proteomic approaches. Annals of Applied Biology - AAB. 143 (1), pp. 81-91. https://doi.org/10.1111/j.1744-7348.2003.tb00272.x

Physiological characterization of 'stay green' mutants in durum wheat

A - Papers appearing in refereed journals
Spano, G., Di Fonzo, N., Perrotta, C., Platani, C., Ronga, G., Lawlor, D. W., Napier, J. A. and Shewry, P. R. 2003. Physiological characterization of 'stay green' mutants in durum wheat. Journal of Experimental Botany. 54, pp. 1415-1420. https://doi.org/10.1093/jxb/erg150

Functional characterisation of two cytochrome b 5-fusion desaturases from Anemone leveillei : the unexpected identification of a fatty acid delta6-desaturase

A - Papers appearing in refereed journals
Whitney, H. M., Michaelson, L. V., Sayanova, O. V., Pickett, J. A. and Napier, J. A. 2003. Functional characterisation of two cytochrome b 5-fusion desaturases from Anemone leveillei : the unexpected identification of a fatty acid delta6-desaturase. Planta. 217 (6), pp. 983-992. https://doi.org/10.1007/s00425-003-1069-5

New chemical signals in plant protection against herbivores and weeds

C1 - Edited contributions to conferences/learned societies
Matthes, M. C., Napier, J. A., Pickett, J. A. and Woodcock, C. M. 2003. New chemical signals in plant protection against herbivores and weeds. Proceedings BCPC International Congress - Crop Science and Technology, Glasgow, 10-12 November 2003 . pp. 1227-1236

Plant stress signalling: understanding and exploiting plant-plant interactions

A - Papers appearing in refereed journals
Pickett, J. A., Rasmussen, H. B., Woodcock, C. M., Matthes, M. C. and Napier, J. A. 2003. Plant stress signalling: understanding and exploiting plant-plant interactions. Biochemical Society Transactions. 31 (1), pp. 123-127. https://doi.org/10.1042/bst0310123

New Elongase Gene And Production Of Δ9-polyunsaturated Fatty Acids (Patent WO 2002/077213 A2)

H2 - Patents applied for
Napier, J. A., Lazarus, C. M., Qi, B. and Lerchl, J. 2002. New Elongase Gene And Production Of Δ9-polyunsaturated Fatty Acids (Patent WO 2002/077213 A2). WO 2002/077213 A2

New Elongase Gene And Production Of Delta 9-polyunsaturated Fatty Acids (Patent CA 2442010 A1)

H2 - Patents applied for
Qi, B, Lerchl, J., Lazarus, C. M. and Napier, J. A. 2002. New Elongase Gene And Production Of Delta 9-polyunsaturated Fatty Acids (Patent CA 2442010 A1). CA 2442010 A1

Cis-jasmone As Semiochemical (Patent EP 1235483 A2)

H1 - Patents granted
Hick, A. J., Pickett, J. A., Wadhams, L. J. and Napier, J. A. 2002. Cis-jasmone As Semiochemical (Patent EP 1235483 A2). EP 1235483 A2

Polysaturated Fatty Acid (pufa) Elongase From Caenorhabditis Elegans (Patent WO 2000/055330 A9)

H2 - Patents applied for
Napier, J. A. 2002. Polysaturated Fatty Acid (pufa) Elongase From Caenorhabditis Elegans (Patent WO 2000/055330 A9). WO 2000/055330 A9

Identification of a cDNA encoding a novel C18-delta9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana

A - Papers appearing in refereed journals
Qi, B., Beaudoin, F., Fraser, T., Stobart, A. K., Napier, J. A. and Lazarus, C. M. 2002. Identification of a cDNA encoding a novel C18-delta9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana. FEBS Letters. 510 (3), pp. 159-165. https://doi.org/10.1016/S0014-5793(01)03247-1

The production of polyunsaturated fatty acids in transgenic plants

A - Papers appearing in refereed journals
Napier, J. A. 2002. The production of polyunsaturated fatty acids in transgenic plants. Inform - International News on Fats, Oils and Related Materials. 13, pp. 769-772.

A new class of lipid desaturase central to sphingolipid biosynthesis and signalling

A - Papers appearing in refereed journals
Napier, J. A., Michaelson, L. V. and Dunn, T. M. 2002. A new class of lipid desaturase central to sphingolipid biosynthesis and signalling. Trends in Plant Science. 7, pp. 475-478.

Plumbing the depths of PUFA biosynthesis: a novel polyketide synthase-like pathway from marine organisms

A - Papers appearing in refereed journals
Napier, J. A. 2002. Plumbing the depths of PUFA biosynthesis: a novel polyketide synthase-like pathway from marine organisms. Trends in Plant Science. 7, pp. 51-54.

Altering specifity of a Ricinus communis cytochrome b5 fusion desaturase

A - Papers appearing in refereed journals
Michaelson, L. V. and Napier, J. A. 2002. Altering specifity of a Ricinus communis cytochrome b5 fusion desaturase. Biochemical Society Transactions. 30 (5), p. A123. https://doi.org/10.1042/bst030a123a

Isolation and characterization of a cDNA encoding a delta8 sphingolipid desaturase from Aquilegia vulgaris

A - Papers appearing in refereed journals
Michaelson, L. V., Longman, A. J., Sayanova, O. V., Stobart, A. K. and Napier, J. A. 2002. Isolation and characterization of a cDNA encoding a delta8 sphingolipid desaturase from Aquilegia vulgaris. Biochemical Society Transactions. 30 (6), pp. 1073-1075. https://doi.org/10.1042/bst0301073

The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase

A - Papers appearing in refereed journals
Han, G., Gable, K., Kohlwein, S. D., Beaudoin, F., Napier, J. A. and Dunn, T. M. 2002. The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. Journal of Biological Chemistry. 277, pp. 35440-35449. https://doi.org/10.1074/jbc.M205620200

Insertional tagging of regulatory sequences in tritordeum; a hexaploid cereal species

A - Papers appearing in refereed journals
Salgueiro, S., Matthes, M. C., Gil, J., Steele, S. H., Savazzini, F., Riley, A. E., Jones, H. D., Lazzeri, P. A. and Barcelo, P. 2002. Insertional tagging of regulatory sequences in tritordeum; a hexaploid cereal species. Theoretical and Applied Genetics. 104, pp. 916-925.

A new class of lipid desaturases: identification of the delta4 sphingoid base desaturase

A - Papers appearing in refereed journals
Garton, S., Michaelson, L. V., Beaudoin, F. and Napier, J. A. 2002. A new class of lipid desaturases: identification of the delta4 sphingoid base desaturase. Biochemical Society Transactions. 30 (6), p. A122. https://doi.org/10.1042/bst030a122c

Targeting and membrane-insertion of a sunflower oleosin in vitro and in Saccharomyces cerevisiae : the central hydrophobic domain contains more than one signal sequence, and directs oleosin insertion into the endoplasmic reticulum membrane using a signal anchor sequence mechanism

A - Papers appearing in refereed journals
Beaudoin, F. and Napier, J. A. 2002. Targeting and membrane-insertion of a sunflower oleosin in vitro and in Saccharomyces cerevisiae : the central hydrophobic domain contains more than one signal sequence, and directs oleosin insertion into the endoplasmic reticulum membrane using a signal anchor sequence mechanism. Planta. 215, pp. 293-303.

A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase

A - Papers appearing in refereed journals
Beaudoin, F., Gable, K., Sayanova, O. V., Dunn, T. and Napier, J. A. 2002. A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. Journal of Biological Chemistry. 277, pp. 11481-11488.

Characterization and modelling of the hydrophobic domain of a sunflower oleosin

A - Papers appearing in refereed journals
Alexander, L. G., Sessions, R. B., Clarke, A. R., Tatham, A. S., Shewry, P. R. and Napier, J. A. 2002. Characterization and modelling of the hydrophobic domain of a sunflower oleosin. Planta. 214, pp. 546-551.

Plant protein families and their relationships to food allergy

A - Papers appearing in refereed journals
Shewry, P. R., Beaudoin, F., Jenkins, J., Griffiths-Jones, S. and Mills, E. N. C. 2002. Plant protein families and their relationships to food allergy. Biochemical Society Transactions. 30 (6), pp. 906-910. https://doi.org/10.1042/bst0300906

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