Plant proteostasis-a proven and promising target for crop improvement - Editorial

A - Papers appearing in refereed journals

Theodoulou, F. L., Orosa-Puente, B., Trujillo, M. and Rubio V. 2022. Plant proteostasis-a proven and promising target for crop improvement - Editorial. Essays in Biochemistry. 66 (2), pp. 75-85.

AuthorsTheodoulou, F. L., Orosa-Puente, B., Trujillo, M. and Rubio V.

The Green Revolution of the 1960s accomplished dramatic increases in crop yields through genetic improvement, chemical fertilisers, irrigation, and mechanisation. However, the current trajectory of population growth, against a backdrop of climate change and geopolitical unrest, predicts that agricultural production will be insufficient to ensure global food security in the next three decades. Improvements to crops that go beyond incremental gains are urgently needed. Plant biology has also undergone a revolution in recent years, through the development and application of powerful technologies including genome sequencing, a pantheon of ‘omics techniques, precise genome editing, and step changes in structural biology and microscopy. Proteostasis- the collective processes that control the protein complement of the cell, comprising synthesis, modification, localisation, and degradation- is a field that has benefitted from these advances. This special issue presents a selection of the latest research in this vibrant field, with a particular focus on protein degradation. In the current article, we highlight the diverse and widespread contributions of plant proteostasis to agronomic traits, suggest opportunities and strategies to manipulate different elements of proteostatic mechanisms for crop improvement, and discuss the challenges involved in bringing these ideas into practice.

KeywordsAutophagy; Ubiquitin proteasome system; Genome editing; Crop improvement; Proteostasis
Year of Publication2022
JournalEssays in Biochemistry
Journal citation66 (2), pp. 75-85
Digital Object Identifier (DOI)
Open accessPublished as bronze (free) open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeTPM - Tailoring Plant Metabolism - Work package 1 (WP1) - High value lipids for health and industry
Publisher's version
Accepted author manuscript
Supplemental file
Output statusPublished
Publication dates
Online05 Aug 2022
Publication process dates
Accepted02 Aug 2022
PublisherPortland Press Ltd

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