A - Papers appearing in refereed journals
Chamberlain, K., Evans, A. A. and Bromilow, R. H. 1996. 1-Octanol/water partition coefficient (Kow) and pKa for ionisable pesticides measured by a pH-metric method. Pesticide Science. 47 (3), pp. 265-271.
|Authors||Chamberlain, K., Evans, A. A. and Bromilow, R. H.|
pK(a) values for a wide range of commonly used ionisable pesticides, together with the log K-ow values of the most lipophilic form of each, have been measured using ps-metric techniques. Examples of acids, bases and multiprotic compounds from the major classes of herbicides, and a number of insecticides and fungicides that contain ionisable groups, are included. The pK(a) and log K-ow values so obtained were generally in good agreement with values taken from the literature that were measured by other methods. The lower limit of log K-ow that could be measured by the pH-metric method lay below the -0.97 obtained for amitrole, but the method could not be applied to glyphosate for which shake-flask measurements indicated log K-ow below -3. The highest log K-ow obtained in this study was 5.12 for pentachlorophenol. The pH-metric technique offers a rapid and convenient method to determine pK(a) and log K-ow for ionisable compounds, especially when utilising an automatic titration system linked to a dedicated computer.
|Year of Publication||1996|
|Journal citation||47 (3), pp. 265-271|
|Digital Object Identifier (DOI)||doi:10.1002/(SICI)1096-9063(199607)47:3<265::AID-PS416>3.0.CO;2-F|
|Open access||Published as non-open access|
|Funder project or code||233|
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