Characterization of the Anopheles funestus group, including Anopheles funestus-like, from Northern Malawi

A - Papers appearing in refereed journals

Vezenegho, S. B., Chiphwanya, J., Hunt, R. H., Coetzee, M., Bass, C. and Koekemoer, L. L. 2013. Characterization of the Anopheles funestus group, including Anopheles funestus-like, from Northern Malawi. Transactions Of The Royal Society Of Tropical Medicine And Hygiene. 107 (12), pp. 753-762.

AuthorsVezenegho, S. B., Chiphwanya, J., Hunt, R. H., Coetzee, M., Bass, C. and Koekemoer, L. L.
Abstract

Background
Limited information is available on malaria vector composition, feeding habits and malaria transmission in northern Malawi. Evidence of mosquito species diversity in this area was established in 2009, when Anopheles funestus-like, a new member of the An. funestus group was described. Additional biological information is needed to identify this species and to understand its role in malaria transmission.

Methods
Anopheline mosquitoes were collected in northern Malawi and analyzed for Plasmodium species infection, blood meal source and susceptibility to insecticides. A new hydrolysis probe assay was designed to identify An. funestus-like.

Results
Anopheles funestus and An. rivulorum predominated in the indoor collections. Most An. funestus-like were collected indoors, mainly fed on animals and were uninfected with P. falciparum. Anopheles funestus showed insecticide resistance to deltamethrin and bendiocarb. A high-precision hydrolysis probe assay was successfully developed to identify An. funestus-like.

Discussion
Four species in the An. funestus group were collected in Karonga. Resistance to deltamethrin and bendiocarb was observed in An. funestus and further investigation is needed on the insecticide resistance mechanisms. Anopheles funestus-like, while collected indoors, is mainly zoophilic and most likely not a malaria vector.

Accession numbers
An. funestus (GenBank accession no. KC771136), An. funestus-like (GenBank accession no. KC771137), An. parensis GenBank accession no. KC771138) and An. vaneedeni GenBank accession no. KC771139).

KeywordsAfrican malaria vector; Identification; Insecticide resistance
Year of Publication2013
JournalTransactions Of The Royal Society Of Tropical Medicine And Hygiene
Journal citation107 (12), pp. 753-762
Digital Object Identifier (DOI)doi:10.1093/trstmh/trt089
Open accessPublished as non-open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeDelivering Sustainable Systems (SS) [ISPG]
BBSRC Institute Career Path Fellowship: A genomic approach to understanding insecticide resistance in crop pests
Output statusPublished
Publication dates
Online01 Dec 2013
Publication process dates
Accepted22 Aug 2013
Copyright licensePublisher copyright
PublisherOxford University Press (OUP)
ISSN0035-9203

Permalink - https://repository.rothamsted.ac.uk/item/8qyvy/characterization-of-the-anopheles-funestus-group-including-anopheles-funestus-like-from-northern-malawi

Restricted files

Publisher's version

Under embargo indefinitely

8 total views
1 total downloads
0 views this month
0 downloads this month