Plant Sciences and the Bioeconomy

TitlePlant Sciences and the Bioeconomy
TypeScience Department
InstituteRothamsted Research
HeadFreddie Theodoulou
Executive AssistantSue Steele

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Floral monsters and murderous mirror images

G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2013. Floral monsters and murderous mirror images. Biochemist. 35(2), p. 3.

Peroxisome membrane proteins: multiple trafficking routes and multiple functions?

A - Papers appearing in refereed journals
Theodoulou, F. L., Bernhardt, K., Linka, N. and Baker, A. 2013. Peroxisome membrane proteins: multiple trafficking routes and multiple functions? Biochemical Journal. 451, pp. 345-352. https://doi.org/10.1042/BJ20130078

Natural variation in grain composition of wheat and related cereals

A - Papers appearing in refereed journals
Shewry, P. R., Hawkesford, M. J., Piironen, V., Lampi, A-M., Gebruers, K., Boros, D., Andresson, A. A. M., Aman, P., Rakszegi, M., Bedo, Z. and Ward, J. L. 2013. Natural variation in grain composition of wheat and related cereals. Journal of Agricultural and Food Chemistry. 61, pp. 8295-8303. https://doi.org/10.1021/jf3054092

Differential defence response due to jasmonate seed treatment in cowpea and tomato against root-knot and potato cyst nematodes

A - Papers appearing in refereed journals
Pankaj, Muttucumaru, N., Powers, S. J., Gaur, H. S., Kurup, S. and Curtis, R. H. C. 2013. Differential defence response due to jasmonate seed treatment in cowpea and tomato against root-knot and potato cyst nematodes. Nematology. 15, pp. 15-21. https://doi.org/10.1163/156854112X641754

Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape (Brassica napus L.)

A - Papers appearing in refereed journals
Kelly, A. A., Shaw, E., Powers, S. J., Kurup, S. and Eastmond, P. J. 2013. Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape (Brassica napus L.). Plant Biotechnology Journal. 11 (3), pp. 355-361. https://doi.org/10.1111/pbi.12021

The modification of plant oil composition via metabolic engineering - better nutrition by design

A - Papers appearing in refereed journals
Haslam, R. P., Ruiz-Lopez, N., Eastmond, P. J., Moloney, M., Sayanova, O. V. and Napier, J. A. 2013. The modification of plant oil composition via metabolic engineering - better nutrition by design. Plant Biotechnology Journal. 11 (2), pp. 157-168. https://doi.org/10.1111/pbi.12012

Diversity of sequences encoded by the Gsp-1 genes in wheat and other grass species

A - Papers appearing in refereed journals
Wilkinson, M. D., Castells-Brooke, N. I. D. and Shewry, P. R. 2013. Diversity of sequences encoded by the Gsp-1 genes in wheat and other grass species. Journal of Cereal Science. 57, pp. 1-9. https://doi.org/10.1016/j.jcs.2012.09.005

The impact agenda: when Gladstone met Faraday

G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2013. The impact agenda: when Gladstone met Faraday. Biochemist. 35(1), p. 3.

Molecular characterization of the fatty alcohol oxidation pathway for wax-ester mobilization in germinated jojoba seeds

A - Papers appearing in refereed journals
Rajangam, A. S., Gidda, S. K., Craddock, C., Mullen, R. T., Dyer, J. M. and Eastmond, P. J. 2013. Molecular characterization of the fatty alcohol oxidation pathway for wax-ester mobilization in germinated jojoba seeds. Plant Physiology. 161, pp. 72-80. https://doi.org/10.1104/pp.112.208264

Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density

A - Papers appearing in refereed journals
Hodge, S., Ward, J. L., Beale, M. H., Bennett, M., Mansfield, J. W. and Powell, G. 2013. Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density. Planta. 237, pp. 1057-1064. https://doi.org/10.1007/s00425-012-1826-4

Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids

A - Papers appearing in refereed journals
De Marcos Lousa, C., Van Roermund, C. W. T., Postis, V. L. G., Dietrich, D., Kerr, I. D., Wanders, R. J. A., Baldwin, S. A., Baker, A. and Theodoulou, F. L. 2013. Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 110, pp. 1279-1284. https://doi.org/10.1073/pnas.1218034110

A SNaPshot assay for the rapid and simple detection of known point mutations conferring resistance to ACCase-inhibiting herbicides in Lolium spp.

A - Papers appearing in refereed journals
Reverte, R. A., Hanley, S. J., Kaundun, S. S., Karp, A. and Moss, S. R. 2013. A SNaPshot assay for the rapid and simple detection of known point mutations conferring resistance to ACCase-inhibiting herbicides in Lolium spp. Weed Research. 53 (1), pp. 12-20. https://doi.org/10.1111/wre.12002

Contents of dietary fibre components and their relation to associated bioactive components in whole grain wheat samples from the HEALTHGRAIN diversity screen

A - Papers appearing in refereed journals
Andersson, A. A. M., Andersson, R., Piironen, V., Lampi, A-M., Nystrom, L., Boros, D., Fras, A., Gebruers, K., Courtin, C. M., Delcour, J. A., Rakszegi, M., Bedo, Z., Ward, J. L., Shewry, P. R. and Aman, P. 2013. Contents of dietary fibre components and their relation to associated bioactive components in whole grain wheat samples from the HEALTHGRAIN diversity screen. Food Chemistry. 136 (3-4), pp. 1243-1248. https://doi.org/10.1016/j.foodchem.2012.09.074

Delta 6 Desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 8329993 B2)

H1 - Patents granted
Napier, J. A. and Sayanova, O. V. 2012. Delta 6 Desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 8329993 B2). US 8329993 B2

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8273958 B2)

H1 - Patents granted
Napier, J. A. and Sayanova, O. V. 2012. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8273958 B2) . US 8273958 B2

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8258371 B2)

H1 - Patents granted
Napier, J. A. and Sayanova, O. V. 2012. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8258371 B2) . US 8258371 B2

Semiochemical (Patent US 8221736 B2)

H1 - Patents granted
Hick, J. A., Pickett, J. A., Wadhams, L. J. and Napier, J. A. 2012. Semiochemical (Patent US 8221736 B2). US 8221736 B2

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent EP 2454278 A1)

H2 - Patents applied for
Bauer, J., Napier, J. A. and Sayanova, O. V. 2012. Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent EP 2454278 A1). EP 2454278 A1

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2012/0124705 A1)

H2 - Patents applied for
Napier, J. A., Bauer , J. and Sayanova, O. V. 2012. Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2012/0124705 A1). US 2012/0124705 A1

Novel Fatty Acid Elongation Components And Uses Thereof (Patent US 2012/0084889 A1)

H2 - Patents applied for
Napier, J. A., Sayanova, O. V. and Beaudoin, F. 2012. Novel Fatty Acid Elongation Components And Uses Thereof (Patent US 2012/0084889 A1) . US 2012/0084889 A1

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent EP 1937805 B1)

H1 - Patents granted
Napier, J. A. and Sayanova, O. V. 2012. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent EP 1937805 B1). EP 1937805 B1

Elongase And Uses Thereof (Patent US 8119861 B2)

H1 - Patents granted
Napier, J. A., Sayanova, O. V. and Venegas, C. M. 2012. Elongase And Uses Thereof (Patent US 8119861 B2) . US 8119861 B2

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 2012/0017332 A1)

H2 - Patents applied for
Napier, J. A. and Sayanova, O. V. 2012. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 2012/0017332 A1) . US 2012/0017332 A1

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 2012/0011618 A1)

H2 - Patents applied for
Napier, J. A. and Sayanova, O. V. 2012. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 2012/0011618 A1) . US 2012/0011618 A1

Draft genome sequence of the Coccolithovirus Emiliania huxleyi virus 202

A - Papers appearing in refereed journals
Nissimov, J. I., Worthy, C. A., Rooks, P., Napier, J. A., Kimmance, S. A., Henn, M. R., Ogata, H. and Allen, M. J. 2012. Draft genome sequence of the Coccolithovirus Emiliania huxleyi virus 202. Journal of Virology. 86 (4), pp. 2380-2381. https://doi.org/10.1128/jvi.06863-11

Draft genome sequence of four Coccolithoviruses: Emiliania huxleyi Virus EhV-88, EhV-201, EhV-207, and EhV-208

A - Papers appearing in refereed journals
Nissimov, J. I., Worthy, C. A., Rooks, P., Napier, J. A., Kimmance, S. A., Henn, M. R., Ogata, H. and Allen, M. J. 2012. Draft genome sequence of four Coccolithoviruses: Emiliania huxleyi Virus EhV-88, EhV-201, EhV-207, and EhV-208. Journal of Virology. 86 (5), pp. 2896-2897. https://doi.org/10.1128/jvi.07046-11

High levels of genetic diversity in Salix viminalis of the Czech Republic as revealed by microsatellite markers

A - Papers appearing in refereed journals
Trybush, S. O., Jahodova, S., Cizkova, L., Karp, A. and Hanley, S. J. 2012. High levels of genetic diversity in Salix viminalis of the Czech Republic as revealed by microsatellite markers. BioEnergy Research. 5 (4), pp. 969-977. https://doi.org/10.1007/s12155-012-9212-4

Metabolic engineering of plant-derived (E)-beta-farnesene synthase genes for a novel type of aphid-resistant genetically modified crop plants

A - Papers appearing in refereed journals
Yu, X-D., Pickett, J. A., Ma, Y-Z., Bruce, T. J. A., Napier, J. A., Jones, H. D. and Xia, L-Q. 2012. Metabolic engineering of plant-derived (E)-beta-farnesene synthase genes for a novel type of aphid-resistant genetically modified crop plants. Journal of Integrative Plant Biology. 54 (5), pp. 282-299. https://doi.org/10.1111/j.1744-7909.2012.01107.x

Science under siege

G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2012. Science under siege. The Biochemist. 34 (5), p. 3.

Reinventing the polytechnic?

G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2012. Reinventing the polytechnic? Biologist. 34(4), p. 3.

Metabolic engineering of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway into transgenic plants

A - Papers appearing in refereed journals
Ruiz-Lopez, N., Sayanova, O. V., Napier, J. A. and Haslam, R. P. 2012. Metabolic engineering of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway into transgenic plants. Journal of Experimental Botany. 63, pp. 2397-2410. https://doi.org/10.1093/jxb/err454

Enhancing the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Arabidopsis thaliana via iterative metabolic engineering and genetic crossing

A - Papers appearing in refereed journals
Ruiz-Lopez, N., Haslam, R. P., Venegas-Caleron, M., Li, T., Bauer, J., Napier, J. A. and Sayanova, O. V. 2012. Enhancing the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Arabidopsis thaliana via iterative metabolic engineering and genetic crossing. Transgenic Research. 21, pp. 1233-1243. https://doi.org/10.1007/s11248-012-9596-0

Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis ECERIFERUM1 and ECERIFERUM3 are core components of a very-long-chain alkane synthesis complex

A - Papers appearing in refereed journals
Bernard, A., Domergue, F., Pascal, S., Jetter, R., Renne, C., Faure, J-D., Haslam, R. P., Napier, J. A., Lessire, R. and Joubes, J. 2012. Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis ECERIFERUM1 and ECERIFERUM3 are core components of a very-long-chain alkane synthesis complex. The Plant Cell. 24, pp. 3106-3118. https://doi.org/10.1105/tpc.112.099796

Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus

A - Papers appearing in refereed journals
Andre, C., Haslam, R. P. and Shanklin, J. 2012. Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus. Proceedings of the National Academy of Sciences of the United States of America. 109, pp. 10107-10112. https://doi.org/10.1073/pnas.1204604109

Promoter variation and transcript divergence in Brassicaceae lineages of FLOWERING LOCUST T

A - Papers appearing in refereed journals
Wang, J., Hopkins, C. J., Hou, J., Zou, X., Wang, C., Long, Y., Kurup, S., King, G. J. and Meng, J. 2012. Promoter variation and transcript divergence in Brassicaceae lineages of FLOWERING LOCUST T. PLOS ONE. 7, p. e47127. https://doi.org/10.1371/journal.pone.0047127

Parental genome imbalance in Brassica oleracea causes asymmetric triploid block

A - Papers appearing in refereed journals
Stoute, A. I., Varenko, V., King, G. J., Scott, R. J. and Kurup, S. 2012. Parental genome imbalance in Brassica oleracea causes asymmetric triploid block. The Plant Journal. 71 (3), pp. 503-516. https://doi.org/10.1111/j.1365-313X.2012.05015.x

A hypomethylated population of Brassica rapa for forward and reverse epi-genetics

A - Papers appearing in refereed journals
Amoah, S., Kurup, S., Rodriguez Lopez, C. M., Welham, S. J., Powers, S. J., Hopkins, C. J., Wilkinson, M. J. and King, G. J. 2012. A hypomethylated population of Brassica rapa for forward and reverse epi-genetics. BMC Plant Biology. 12, p. 193 (17pp). https://doi.org/10.1186/1471-2229-12-193

Could Jurassic Park ever come true?

G - Articles in popular magazines and other technical publications
Theodoulou, F. L. 2012. Could Jurassic Park ever come true? Biochemist. 34(6), p. 3.

A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase

A - Papers appearing in refereed journals
Criswell, J., Potter, K., Shephard, F., Beale, M. H. and Peters, R. J. 2012. A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase. Organic Letters. 14, pp. 5828-5831. https://doi.org/10.1021/ol3026022

SLO2, a mitochondrial pentatricopeptide repeat protein affecting several RNA editing sites, is required for energy metabolism

A - Papers appearing in refereed journals
Zhu, Q., Dugardeyn, J., Zhang, C., Takenaka, M., Kuhn, K., Craddock, C., Smalle, J., Karampelias, M., Denecke, J., Peters, J., Gerats, T., Brennicke, A., Eastmond, P. J., Meyer, E. H. and Van Der Straeten, D. 2012. SLO2, a mitochondrial pentatricopeptide repeat protein affecting several RNA editing sites, is required for energy metabolism. The Plant Journal. 71 (5), pp. 836-849. https://doi.org/10.1111/j.1365-313X.2012.05036.x