Keywan Hassani-Pak

NameKeywan Hassani-Pak
Job titleSenior Research Scientist - Head of Bioinformatics
Email addresskeywan.hassani-pak@rothamsted.ac.uk
DepartmentComputational and Analytical Sciences
Research clusterCAS: Genomics and Bioinformatics
ORCIDhttps://orcid.org/0000-0001-9625-0511
OfficeHarpenden

Research outputs

Basic LEUCINE ZIPPER TRANSCRIPTION FACTOR 67 transactivates DELAY OF GERMINATION 1 to establish primary seed dormancy in Arabidopsis

Bryant, F. M., Hughes, D. J., Hassani-Pak, K. and Eastmond, P. J. 2019. Basic LEUCINE ZIPPER TRANSCRIPTION FACTOR 67 transactivates DELAY OF GERMINATION 1 to establish primary seed dormancy in Arabidopsis. The Plant Cell.

Natural variation in acyl editing is a determinant of seed storage oil composition

Menard, G. N., Bryant, F. M., Kelly, A. A., Craddock, C. P., Lavagi, I., Hassani-Pak, K., Kurup, S. and Eastmond, P. J. 2018. Natural variation in acyl editing is a determinant of seed storage oil composition. Scientific Reports. 8, p. 17346.

KnetMaps: a BioJS component to visualize biological knowledge networks

Singh, A., Rawlings, C. J. and Hassani-Pak, K. 2018. KnetMaps: a BioJS component to visualize biological knowledge networks. F1000Research. 7, p. 1651.

Towards FAIRer Biological Knowledge Networks Using a Hybrid Linked Data and Graph Database Approach

Brandizi, M., Singh, A., Rawlings, C. J. and Hassani-Pak, K. 2018. Towards FAIRer Biological Knowledge Networks Using a Hybrid Linked Data and Graph Database Approach. Journal of Integrative Bioinformatics. 15 (3), pp. 1-10.

The Role of Trehalose 6-Phosphate in Crop Yield and Resilience

Paul, M. J., Gonzalez-Uriarte, A., Griffiths, C. A. and Hassani-Pak, K. 2018. The Role of Trehalose 6-Phosphate in Crop Yield and Resilience. Plant Physiology. 177, pp. 12-23.

Transcriptome changes induced by arbuscular mycorrhizal fungi in sunflower (Helianthus annuus L.) roots

Vangelisti, A., Natali, L., Bernardi, R., Sbrana, C., Turrini, A., Hassani-Pak, K., Hughes, D. J., Cavallini, A., Giovannetti, M. and Giordani, T. 2018. Transcriptome changes induced by arbuscular mycorrhizal fungi in sunflower (Helianthus annuus L.) roots. Scientific Reports. 8 (4), pp. 1-14.

Knowledge Discovery in Biological Databases for Revealing Candidate Genes Linked to Complex Phenotypes

Hassani-Pak, K. and Rawlings, C. J. 2017. Knowledge Discovery in Biological Databases for Revealing Candidate Genes Linked to Complex Phenotypes. Journal of Integrative Bioinformatics. 14 (1), pp. 1-9.

Spatiotemporal expression patterns of wheat amino acid transporters reveal their putative roles in nitrogen transport and responses to abiotic stress

Wan, Y., King, R., Mitchell, R. A. C., Hassani-Pak, K. and Hawkesford, M. J. 2017. Spatiotemporal expression patterns of wheat amino acid transporters reveal their putative roles in nitrogen transport and responses to abiotic stress. Scientific Reports. 7 (1), p. 5461.

Genome wide analysis of fatty acid desaturation and its response to temperature

Menard, G. N., Martin-Moreno, J., Bryant, F. M., Munoz-Azcarate, O., Kelly, A. A., Hassani-Pak, K., Kurup, S. and Eastmond, P. J. 2017. Genome wide analysis of fatty acid desaturation and its response to temperature. Plant Physiology. 173 (3), pp. 1594-1605.

KnetMiner - An integrated data platform for gene mining and biological knowledge discovery

Hassani-Pak, K. 2017. KnetMiner - An integrated data platform for gene mining and biological knowledge discovery. F - Theses Rothamsted Research Computational and Analytical Sciences

Developing integrated crop knowledge networks to advance candidate gene discovery

Hassani-Pak, K., Esch, M., Castellote, M., Hindle, M. M., Lysenko, A., Taubert, J. and Rawlings, C. J. 2016. Developing integrated crop knowledge networks to advance candidate gene discovery. Applied & Translational Genomics. 11, pp. 18-26.

Insecticide resistance mediated by an exon skipping event.

Berger, M., Puinean, A. M., Randall, E., Zimmer, C. T., Silva, W. M., Bielza, P., Field, L. M., Hughes, D. J., Mellor, I., Hassani-Pak, K., Siqueira, H. A. A., Williamson, M. S. and Bass, C. 2016. Insecticide resistance mediated by an exon skipping event. Molecular Ecology. 25 (22), pp. 5692-5704.

Mutation scanning in wheat by exon capture and next-generation sequencing

King, R., Bird, N., Ramirez-Gonzalez, R., Coghill, J. A., Patil, A., Hassani-Pak, K., Uauy, C. and Phillips, A. L. 2015. Mutation scanning in wheat by exon capture and next-generation sequencing. PLOS ONE. 10, p. e0137549.

The completed genome sequence of the pathogenic ascomycete fungus Fusarium graminearum

King, R., Urban, M., Hammond-Kosack, M. C. U., Hassani-Pak, K. and Hammond-Kosack, K. E. 2015. The completed genome sequence of the pathogenic ascomycete fungus Fusarium graminearum. BMC Genomics. 16, p. 544.

Whole-genome analysis of Fusarium graminearum insertional mutants identifies virulence associated genes and unmasks untagged chromosomal deletions

Urban, M., King, R., Hassani-Pak, K. and Hammond-Kosack, K. E. 2015. Whole-genome analysis of Fusarium graminearum insertional mutants identifies virulence associated genes and unmasks untagged chromosomal deletions. BMC Genomics. 16, p. 261.

Transcriptome and metabolite profiling of the infection cycle of Zymoseptoria tritici on wheat reveals a biphasic interaction with plant immunity involving differential pathogen chromosomal contributions and a variation on the hemibiotrophic lifestyle definition

Rudd, J. J., Kanyuka, K., Hassani-Pak, K., Derbyshire, M., Andongabo, A. E., Devonshire, J., Lysenko, A., Saqi, M., Desai, N. M., Powers, S. J., Hooper, J., Ambroso, L., Bharti, A., Farmer, A., Hammond-Kosack, K. E., Dietrich, R. A. and Courbot, M. 2015. Transcriptome and metabolite profiling of the infection cycle of Zymoseptoria tritici on wheat reveals a biphasic interaction with plant immunity involving differential pathogen chromosomal contributions and a variation on the hemibiotrophic lifestyle definition. Plant Physiology. 167, pp. 1158-1185.

A tale of one fungal pathogen of wheat: how it evades host surveillance and then hijacks host defences

Kanyuka, K., Lysenko, A., Saqi, M., Derbyshire, M., Andongabo, A. E., Hassani-Pak, K., Hammond-Kosack, K. E., Courbot, M. and Rudd, J. J. 2014. A tale of one fungal pathogen of wheat: how it evades host surveillance and then hijacks host defences. Abstracts 16th International Congress on Molecular Plant-Microbe Interactions (IS-MPMI 2014), Rhodes, 6-10 July 2014 . pp. P069

Identification and analysis of differentially expressed genes in the wheat- Zymoseptoria tritici interaction

Kanyuka, K., Andongabo, A. E., Hassani-Pak, K., Powers, S. J., Lysenko, A., Saqi, M., Derbyshire, M., Lee, W-S., Hammond-Kosack, K. E., Courbot, M. and Rudd, J. J. 2014. Identification and analysis of differentially expressed genes in the wheat- Zymoseptoria tritici interaction. Abstracts Plant Genomics Congress, London, 12-13 May 2014 .

A query suggestion workflow for life science IR-systems

Esch, M., Chen, J., Weise, S., Hassani-Pak, K., Scholz, U. and Lange, M. 2014. A query suggestion workflow for life science IR-systems. Journal of Integrative Bioinformatics. 11, p. 237.

Secondary cell wall composition and candidate gene expression in developing willow (Salix purpurea) stems

Wan, Y., Gritsch, C., Tryfona, T., Ray, M. J., Andongabo, A. E., Hassani-Pak, K., Jones, H. D., Dupree, P., Karp, A., Shewry, P. R. and Mitchell, R. A. C. 2014. Secondary cell wall composition and candidate gene expression in developing willow (Salix purpurea) stems. Planta. 239, pp. 1041-1053.

Ondex Web: web-based visualization and exploration of heterogeneous biological networks

Taubert, J., Hassani-Pak, K., Castells-Brooke, N. I. D. and Rawlings, C. J. 2014. Ondex Web: web-based visualization and exploration of heterogeneous biological networks. Bioinformatics. 30, pp. 1034-1035.

Gaining confidence in cross-species annotation transfer: from simple molecular function to complex phenotypic traits

Defoin-Platel, M., Hassani-Pak, K. and Rawlings, C. J. 2011. Gaining confidence in cross-species annotation transfer: from simple molecular function to complex phenotypic traits. Systems Approaches to Crop Improvement. Aspects of Applied Biology 107 . Association of Applied Biologists (AAB) Wellesbourne Warwick . pp. 79-87

Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis

Lysenko, A., Defoin-Platel, M., Hassani-Pak, K., Taubert, J., Hodgman, C., Rawlings, C. J. and Saqi, M. 2011. Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis. BMC Bioinformatics. 12, p. 203 (14pp).

Enhancing data integration with text analysis to find proteins implicated in plant stress response

Hassani-Pak, K., Legaie, R., Canevet, C., Van Den Berg, H. A., Moore, J. D. and Rawlings, C. J. 2010. Enhancing data integration with text analysis to find proteins implicated in plant stress response. Journal of Integrative Bioinformatics. 7, p. 121 (13pp).

Graph-based sequence annotation using a data integration approach

Pesch, R., Lysenko, A., Hindle, M. M., Hassani-Pak, K., Thiele, R., Rawlings, C. J., Kohler, J. and Taubert, J. 2008. Graph-based sequence annotation using a data integration approach. Journal of Integrative Bioinformatics. 5(2):94, p. 15pp.

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