DFW - Designing Future Wheat - Work package 2 (WP2) - Added value and resilience

Repository project

Project dates01 Apr 2017 to end of 31 Mar 2022
Researchers
Principal InvestigatorKim Hammond-Kosack
FunderBiotechnology and Biological Sciences Research Council
Project numberI0250
DepartmentPlant Sciences
Research fish codeBBS/E/C/000I0250
Grant IDBBS/E/C/000I0250

Outputs

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Effect of Intake of Food Hydrocolloids of Bacterial Origin on the Glycemic Response in Humans: Systematic Review and Narrative Synthesis.

A - Papers appearing in refereed journals
Alshammari, N. A., Taylor, M. A., Stevenson, R., Gouseti, O., Alyami, J., Muttakin, S., Bakalis, S., Lovegrove, A., Aithal, G. P. and Marciani, L. 2021. Effect of Intake of Food Hydrocolloids of Bacterial Origin on the Glycemic Response in Humans: Systematic Review and Narrative Synthesis. Nutrients. 13 (7), p. 2407. https://doi.org/10.3390/nu13072407

Effect of semolina pudding prepared from starch branching enzyme IIa and b mutant wheat on glycaemic response in vitro and in vivo: a randomised controlled pilot study

A - Papers appearing in refereed journals
Corrado, M., Cherta-Murillo, A., Chambers, E. S., Wood, A., Plummer, A., Lovegrove, A., Edwards, C. H., Frost, G. S. and Hazard, B. A. 2020. Effect of semolina pudding prepared from starch branching enzyme IIa and b mutant wheat on glycaemic response in vitro and in vivo: a randomised controlled pilot study. Food and Function. 11, pp. 617-627. https://doi.org/10.1039/c9fo02460c

Effector-mediated partial and nonhost disease resistance in wheat

A - Papers appearing in refereed journals
Rudd, J. J. 2023. Effector-mediated partial and nonhost disease resistance in wheat. New Phytologist. 238, pp. 1340-1342. https://doi.org/10.1111/nph.18872

Effects of drying methods and temperatures on protein, pasting, and thermal properties of white floury corn

A - Papers appearing in refereed journals
Da Silva Timm, N., Lang, G. H., Ramos, A. H., Ferreira, C. D. and Oliveira, M. 2020. Effects of drying methods and temperatures on protein, pasting, and thermal properties of white floury corn. Journal of food processing and preservation. 2020, p. e14767. https://doi.org/10.1111/jfpp.14767

Effects of Organic and Conventional Crop Nutrition on Profiles of Polar Metabolites in Grain of Wheat

A - Papers appearing in refereed journals
Shewry, P. R., Rakszegi, M., Lovegrove, A., Amos, D., Corol, D. I., Tawfike, A., Miko, P. and Ward, J. L. 2018. Effects of Organic and Conventional Crop Nutrition on Profiles of Polar Metabolites in Grain of Wheat. Journal of Agricultural and Food Chemistry - JAFC. 66 (21), pp. 5346-5351. https://doi.org/10.1021/acs.jafc.8b01593

Elite UK winter wheat cultivars differ in their ability to support the colonisation of beneficial root-infecting fungi

A - Papers appearing in refereed journals
Osborne, S., Mcmillan, V. E., White, R. P. and Hammond-Kosack, K. E. 2018. Elite UK winter wheat cultivars differ in their ability to support the colonisation of beneficial root-infecting fungi. Journal of Experimental Botany. 69 (12), pp. 3103-3115. https://doi.org/10.1093/jxb/ery136

Ensembl Genomes 2018: an integrated omics infrastructure for non-vertebrate species

A - Papers appearing in refereed journals
Kersey, P. J., Allen, J. E., Allot, A., Barba, M., Boddu, S., Bolt, B. J., Carvalho-Silva, D., Christensen, M., Davis, P., Grabmueller, C., Kumar, N., Liu, Z., Maurel, T., Moore, B., Mcdowall, M. D., Maheswari, U., Naamati, G., Newman, V., Ong, C. K., Paulini, M., Pedro, H., Perry, E., Russell, M., Sparrow, H., Tapanari, E., Taylor, K., Vullo, A., Williams, G., Zadissia, A., Olson, A., Stein, J., Wei, S., Tello-Ruiz, M., Ware, D., Luciani, A., Potter, S., Finn, R. D., Urban, M., Hammond-Kosack, K. E., Bolser, D. M., De Silva, N., Howe, K. L., Langridge, N., Maslen, G., Staines, D. M. and Yates, A. 2018. Ensembl Genomes 2018: an integrated omics infrastructure for non-vertebrate species. Nucleic Acids Research. 46 (D1), pp. D802-D808. https://doi.org/10.1093/nar/gkx1011

Excretion of avenanthramides, phenolic acids and their major metabolites following intake of oat bran

A - Papers appearing in refereed journals
Schar, M. Y., Corona, G., Soycan, G., Dine, C., Kristek, A., Alsahrif, S. N. S., Behrends, V., Lovegrove, A., Shewry, P. R. and Spencer, J. P. E. 2018. Excretion of avenanthramides, phenolic acids and their major metabolites following intake of oat bran. Molecular Nutrition & Food Research. 62 (2), p. 1700499. https://doi.org/10.1002/mnfr.201700499

Exploiting natural and induced variation to improve the content and composition of dietary fibre in wheat grain

Conference paper
Lovegrove, A., Plummer, A., Wood, A., Passmore, D., Kosik, O., Reynolds, S., Freeman, J., Pellny, T. K., Mitchell, R. A. C., Ulker, M., Rakszegi, M., Bedo, Z, Perretant, M. R., Charmete, G, Wingen, L., Leverington, M., Mondal, S., Singh, R., Guzman, C., Griffiths, S. and Shewry, P. R. 2018. Exploiting natural and induced variation to improve the content and composition of dietary fibre in wheat grain. 13th International Gluten Workshop. CIMMYT, Mexico 14 Mar 2018

Exploring the role of cereal dietary fiber in digestion

A - Papers appearing in refereed journals
Gouseti, O., Lovegrove, A., Kosik, O., Fryer, P. J., Mills, E. C. N., Gates, F. K., Tucker, G., Latty, C., Shewry, P. R. and Bakalis, S. 2019. Exploring the role of cereal dietary fiber in digestion. Journal of Agricultural and Food Chemistry - JAFC. 67 (30), pp. 8419-8424. https://doi.org/10.1021/acs.jafc.9b01847

Fluidized‐bed drying of black rice grains: Impact on cooking properties, in vitro starch digestibility, and bioaccessibility of phenolic compounds

A - Papers appearing in refereed journals
Lang, G. H., Da Silva Lindemann, I., Goebel, J. T., Ferriera, C. D., Dos Santos Acunha, T. and Oliveira, M. 2020. Fluidized‐bed drying of black rice grains: Impact on cooking properties, in vitro starch digestibility, and bioaccessibility of phenolic compounds . Journal of Food Science. 85 (6), pp. 1717-1724. https://doi.org/10.1111/1750-3841.15145

FODMAPs in Wheat

B - Book chapters etc edited externally
Grausgruber, H., Lovegrove, A., Shewry, P. R. and Bekes, F. 2020. FODMAPs in Wheat. in: Igrejas, G., Ikeda, T. M. and Guzman, C. (ed.) Wheat Quality For Improving Processing And Human Health Switzerland Springer. pp. 517-534

Foxtail mosaic virus: a new viral vector for protein expression in cereals

A - Papers appearing in refereed journals
Bouton, C., King, R., Chen, H., Azhakanandam, K., Bieri, S., Hammond-Kosack, K. E. and Kanyuka, K. 2018. Foxtail mosaic virus: a new viral vector for protein expression in cereals. Plant Physiology. 177 (4), pp. 1352-1367. https://doi.org/10.1104/pp.17.01679

Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

A - Papers appearing in refereed journals
Brown, N. A., Schrevens, S., Van Dijck, P. and Goldman, G. H. 2018. Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control. Nature Microbiology. 3 (4), pp. 402-414. https://doi.org/10.1038/s41564-018-0127-5

Fungal plant pathogen "mutagenomics" reveals tagged and untagged mutations in Zymoseptoria tritici and identifies SSK2 as key morphogenesis and stress-responsive virulence factor

A - Papers appearing in refereed journals
Blyth, H., Smith, D., King, R., Bayon, C., Ashfield, T., Walpole, H., Venter, E., Kanyuka, K. and Rudd, J. J. 2023. Fungal plant pathogen "mutagenomics" reveals tagged and untagged mutations in Zymoseptoria tritici and identifies SSK2 as key morphogenesis and stress-responsive virulence factor. Frontiers in Plant Science. 14, p. 1140824. https://doi.org/10.3389/fpls.2023.1140824

GCR1 and GPA1 coupling regulates nitrate, cell wall, immunity and light responses in Arabidopsis

A - Papers appearing in refereed journals
Chakraborty, N., Kanyuka, K., Kumar Jaiswal, D., Kumar, A., Arora, V., Malik, A., Gupta, N., Hooley, R. and Raghuram, N. 2019. GCR1 and GPA1 coupling regulates nitrate, cell wall, immunity and light responses in Arabidopsis. Scientific Reports. 9, p. 5838. https://doi.org/10.1038/s41598-019-42084-2

Genetic variation in wheat grain quality is associated with differences in the galactolipid content of flour and the gas bubble properties of dough liquor

A - Papers appearing in refereed journals
Min, B., Salt, L., Wilde, P., Kosik, O., Hassall, K. L., Przewieslik-Allen, A., Burridge, A. J., Poole, M., Snape, J., Wingen, L., Haslam, R. P., Griffiths, S. and Shewry, P. R. 2020. Genetic variation in wheat grain quality is associated with differences in the galactolipid content of flour and the gas bubble properties of dough liquor. Food Chemistry. 60, p. 100093. https://doi.org/10.1016/j.fochx.2020.100093

Gradients in compositions in the starchy endosperm of wheat have implications for milling and processing

A - Papers appearing in refereed journals
Tosi, P., He, J., Lovegrove, A., Gonzalez-Thuillier, I., Penson, S. and Shewry, P. R. 2018. Gradients in compositions in the starchy endosperm of wheat have implications for milling and processing. Trends In Food Science & Technology. 82, pp. 1-7. https://doi.org/10.1016/j.tifs.2018.09.027

Health Hazards Associated with Wheat and Gluten Consumption in Susceptible Individuals and Status of Research on Dietary Therapies

B - Book chapters etc edited externally
Rustgi, S., Shewry, P. R. and Brouns, F. 2020. Health Hazards Associated with Wheat and Gluten Consumption in Susceptible Individuals and Status of Research on Dietary Therapies. in: Igrejas, G., Ikeda, T. M. and Guzmán, C. (ed.) Wheat Quality For Improving Processing And Human Health Switzerland Springer. pp. 471-515

Historical changes in the contents and compositions of fibre components and polar metabolites in white wheat flour

A - Papers appearing in refereed journals
Lovegrove, A., Pellny, T. K., Hassall, K. L., Plummer, A., Wood, A., Bellisai, A., Przewieslik-Allen, A., Burridge, A. J., Ward, J. L. and Shewry, P. R. 2020. Historical changes in the contents and compositions of fibre components and polar metabolites in white wheat flour. Scientific Reports. 10, p. 5920. https://doi.org/10.1038/s41598-020-62777-3

ICC Handbook of 21st Century Cereal Science and Technology 1st Edition

E - Books edited/written by staff member, alone/with others
Shewry, P. R. Shewry, P. R., Koshel, H. and Taylor, J. R. N. (ed.) 2023. ICC Handbook of 21st Century Cereal Science and Technology 1st Edition. Elsevier.

Identification and functional characterisation of a locus for target site integration in Fusarium graminearum

A - Papers appearing in refereed journals
Darino, M., Urban, M., Kaur, N., Wood, A. K. M., Smith, D., Grimwade-Mann, M., Beacham, A. and Hammond-Kosack, K. E. 2024. Identification and functional characterisation of a locus for target site integration in Fusarium graminearum. Fungal Biology and Biotechnology. 11 (2), pp. 1-21. https://doi.org/10.1186/s40694-024-00171-8

Identification of a major QTL and associated molecular marker for high arabinoxylan fibre in white wheat flour

A - Papers appearing in refereed journals
Lovegrove, A., Wingen, L. U., Plummer, A., Wood, A., Passmore, D., Kosik, O., Freeman, J., Mitchell, R. A. C., Hassall, K. L., Ulker, M., Tremmel-Bede, K., Rakszegi, M., Bedo, Z., Perretant, M-R., Charmet, G., Pont, C., Salse, J., Leverington Waite, M., Orford, S., Burridge, A., Pellny, T. K., Shewry, P. R. and Griffiths, S. 2020. Identification of a major QTL and associated molecular marker for high arabinoxylan fibre in white wheat flour. PLOS ONE. 15 (2), p. e0227826. https://doi.org/10.1371/journal.pone.0227826

Identification of Traits Underpinning Good Breadmaking Performance of Wheat Grown with Reduced Nitrogen Fertilisation

A - Papers appearing in refereed journals
Shewry, P. R., Wood, A., Hassall, K. L., Pellny, T. K., Riche, A. B., Hussain, A., Shi, Z., Mosleth, E. F., Charlton, M., Poole, M., Jones, S., Newton, K., Penson, S., Tucker, G., Griffiths, S. and Hawkesford, M. J. 2023. Identification of Traits Underpinning Good Breadmaking Performance of Wheat Grown with Reduced Nitrogen Fertilisation. Journal of the Science of Food and Agriculture. 103 (15), pp. 7664-7672. https://doi.org/10.1002/jsfa.12848

Identifying aphid resistance in the ancestral wheat Triticum monococcum under field conditions.

A - Papers appearing in refereed journals
Simon, A. L., Caulfield, J. C., Hammond-Kosack, K. E., Field, L. M. and Aradottir, G. I. 2021. Identifying aphid resistance in the ancestral wheat Triticum monococcum under field conditions. Scientific Reports. 11, p. 13495. https://doi.org/10.1038/s41598-021-92883-9

Improving starch and fibre in wheat grain for human health

A - Papers appearing in refereed journals
Shewry, P. R., Hazard, B., Lovegrove, A. and Uauy, C. 2020. Improving starch and fibre in wheat grain for human health. The Biochemist. 42 (4), pp. 40-45. https://doi.org/10.1042/BIO20200051

Improving wheat as a source of iron and zinc for global nutrition

A - Papers appearing in refereed journals
Balk, J., Connorton J. M., Wan, Y., Lovegrove, A., Moore, K. L., Uauy, C., Sharp, P. A. and Shewry, P. R. 2019. Improving wheat as a source of iron and zinc for global nutrition. Nutrition Bulletin. 44 (1), pp. 53-59. https://doi.org/10.1111/nbu.12361

Improving wheat protein quality for breadmaking: The role of biotechnology

B - Book chapters etc edited externally
Shewry, P. R. and Jones, H. D. 2020. Improving wheat protein quality for breadmaking: The role of biotechnology. in: Breadmaking Improving Quality 3rd Edition UK Elsevier. pp. 261-288

Inter-genome comparison of the Quorn fungus Fusarium venenatum and the closely related plant infecting pathogen Fusarium graminearum

A - Papers appearing in refereed journals
King, R., Brown, N. A., Urban, M. and Hammond-Kosack, K. E. 2018. Inter-genome comparison of the Quorn fungus Fusarium venenatum and the closely related plant infecting pathogen Fusarium graminearum. BMC Genomics. 19, p. 269. https://doi.org/10.1186/s12864-018-4612-2

International collaboration on wheat quality and safety

C2 - Non-edited contributions to conferences
Ikeda, T. M., Juhasz, A., Rogers, J., Shewry, P. R., Lullien-Pellerin, V., Chulze, S., Giraldo, P., Igrjas, G., Ahmed, R., Pena, R. J. and Guzman, C. 2018. International collaboration on wheat quality and safety. 13th International Gluten Workshop. CIMMYT, Mexico 14 Mar 2018

Is bread bad for health?

A - Papers appearing in refereed journals
Brouns, F., Geisslitz, S. and Shewry, P. R. 2022. Is bread bad for health? Journal of Cereal Science. 105, p. 103447. https://doi.org/10.1016/j.jcs.2022.103447

Loss of AvrSr50 by somatic exchange in stem rust leads to virulence for Sr50 resistance in wheat

A - Papers appearing in refereed journals
Chen, J., Upadhyaya, N. M., Ortiz, D., Sperschneider, J., Li, F., Bouton, C., Breen, S., Dong, C., Xu, B., Zhang, X., Mago, R., Newell, K., Xia, X., Bernoux, M., Taylor, J. M., Steffenson, B., Jin, Y., Zhang, P., Kanyuka, K., Figueroa, M., Ellis, J. G., Park, R. F. and Dodds, P. N. 2017. Loss of AvrSr50 by somatic exchange in stem rust leads to virulence for Sr50 resistance in wheat. Science - AAAS. 358 (6370), pp. 1607-1610. https://doi.org/10.1126/science.aao4810

Loss of starch synthase IIIa changes starch molecular structure and granule morphology in grains of hexaploid bread wheat.

A - Papers appearing in refereed journals
Fahy, B., Gonzalez, O., Savva, G. M., Ahn-Jarvis, J. H., Warren, F. J., Dunn, J., Lovegrove, A. and Hazard, B. A 2022. Loss of starch synthase IIIa changes starch molecular structure and granule morphology in grains of hexaploid bread wheat. Scientific Reports. 12, p. 10806. https://doi.org/10.1038/s41598-022-14995-0

Loss of TaIRX9b gene function in wheat decreases chain length and amount of arabinoxylan in grain but increases cross-linking

A - Papers appearing in refereed journals
Pellny, T. K., Wood, A., Freeman, J., Halsey, K., Plummer, A., Kosik, O., Shewry, P. R., Lovegrove, A., Phillips, A. L. and Mitchell, R. A. C. 2020. Loss of TaIRX9b gene function in wheat decreases chain length and amount of arabinoxylan in grain but increases cross-linking. Plant Biotechnology Journal. pp. 1-12. https://doi.org/10.1111/pbi.13393

Mapping Coeliac Toxic Motifs in the Prolamin Seed Storage Proteins of Barley, Rye, and Oats Using a Curated Sequence Database

A - Papers appearing in refereed journals
Daly, M., Bromilow, S. N., Nitride, C., Shewry, P. R., Gethings, L. A. and Mills, E. N. C 2020. Mapping Coeliac Toxic Motifs in the Prolamin Seed Storage Proteins of Barley, Rye, and Oats Using a Curated Sequence Database. Frontiers in Nutrition. 7, p. 87. https://doi.org/10.3389/fnut.2020.00087

Modern Wheat

G - Articles in popular magazines and other technical publications
Shewry, P. R. and Lovegrove, A. 2020. Modern Wheat. Milling and Grain. 131 (6), pp. 50-52.

Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota

A - Papers appearing in refereed journals
Kristek, A., Wiese, M., Heuer, P., Kosik, O., Schar, M. Y., Soycan, G., Alsharif, S., Kuhnle, G. G. C., Walton, G. and Spencer, J. P. E. 2019. Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota. British Journal Of Nutrition. 121 (5), pp. 549-559. https://doi.org/10.1017/S0007114518003501

Phenotypic, comparative genomic and transcriptomic analysis of recently collected European Zymoseptoria tritici strains

C2 - Non-edited contributions to conferences
Chen, H., Bayon, C., King, R., Torriani, S. F. F., Bieri, S., Kanyuka, K., Hammond-Kosack, K. E. and Rudd, J. J. 2017. Phenotypic, comparative genomic and transcriptomic analysis of recently collected European Zymoseptoria tritici strains. Zymoseptoria Meeting, 2017, Kiel, Germany.

Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophore or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat

A - Papers appearing in refereed journals
Derbyshire, M. C., Gohari, A. M., Mehrabi, R., Kilaru, S., Steinberg, G., Ali, S., Bailey, A., Hammond-Kosack, K. E., Kema, G. H. J. and Rudd, J. J. 2018. Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophore or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat. Scientific Reports. 8 (17069). https://doi.org/10.1038/s41598-018-35223-8

Plant pathogen effector proteins as manipulators of host microbiomes?

A - Papers appearing in refereed journals
Snelder, N. C., Kettles, G. J., Rudd, J. J. and Thomma, B. P. H. J. 2018. Plant pathogen effector proteins as manipulators of host microbiomes? Molecular Plant Pathology. 19 (2), pp. 257-259. https://doi.org/10.1111/mpp.12628