PS: Lipid Metabolic Engineering and Synthetic Biology

TitlePS: Lipid Metabolic Engineering and Synthetic Biology
TypeResearch cluster

Outputs

Sort by: Date Title

Nutritional enhancement in plants – green and greener

A - Papers appearing in refereed journals
Napier, J. A. and Sayanova, O. V. 2020. Nutritional enhancement in plants – green and greener. Current Opinion in Biotechnology. 61 (February), pp. 122-127.

Characterisation of Oil Palm Acyl-CoA-Binding Proteins and Correlation of their Gene Expression with Oil Synthesis

A - Papers appearing in refereed journals
Amiruddin, N., Chan, P-K., Azizi, N., Morris, P. E., Cham, K-L., Ong, P. W., Rosli, R., Masura, S. S., Murphy, D. J., Sambanthamurthi, R., Haslam, R. P., Chye, M-L., Harwood, J. L. and Low, E-T. L. 2019. Characterisation of Oil Palm Acyl-CoA-Binding Proteins and Correlation of their Gene Expression with Oil Synthesis. Plant and cell physiology. pcz237.

Arabidopsis cytosolic acyl-CoA-binding proteins function in determining seed oil composition

A - Papers appearing in refereed journals
Guo, Z. H., Ye, Z. W., Haslam, R. P., Michaelson, L. V., Napier, J. A. and Chye, M. L. 2019. Arabidopsis cytosolic acyl-CoA-binding proteins function in determining seed oil composition. Plant Direct. 3 (12), p. e00182.

The overexpression of rice ACYL-CoA-BINDING PROTEIN2 increases grain size and bran oil content in transgenic rice

A - Papers appearing in refereed journals
Guo, Z.-H., Haslam, R. P., Michaelson, L. V., Young, E. C., Lung, S. C., Napier, J. A. and Chye, M.L. 2019. The overexpression of rice ACYL-CoA-BINDING PROTEIN2 increases grain size and bran oil content in transgenic rice. The Plant Journal.

Engineering the stereoisomeric structure of seed oil to mimic human milk fat

A - Papers appearing in refereed journals
Van-Erp, H., Bryant, F. M., Martin-Moreno, J., Michaelson, L. V., Bhutada, G. and Eastmond, P. J. 2019. Engineering the stereoisomeric structure of seed oil to mimic human milk fat. Proceedings of the National Academy of Sciences of the United States of America - PNAS. 116 (42), pp. 20947-20952.

Phosphorus Use Efficiency and Fertilizers: future opportunities for improvements

A - Papers appearing in refereed journals
Blackwell, M. S. A., Darch, T. and Haslam, R. P. 2019. Phosphorus Use Efficiency and Fertilizers: future opportunities for improvements. Frontiers of Agricultural Science and Engineering. 6 (4), pp. 332-340.

Multifunctionalizing the marine diatom Phaeodactylum tricornutum for sustainable co-production of omega-3 long chain polyunsaturated fatty acids and recombinant phytase

A - Papers appearing in refereed journals
Pudney, A., Gandini, C., Economou, C., Smith, Richard T., Goddard, P., Napier, J. A., Spicer, A. and Sayanova, O. V. 2019. Multifunctionalizing the marine diatom Phaeodactylum tricornutum for sustainable co-production of omega-3 long chain polyunsaturated fatty acids and recombinant phytase. Scientific Reports. 9 (1), p. 11444.

Sphingolipids: towards an integrated view of metabolism during the plant stress response

A - Papers appearing in refereed journals
Huby, E., Napier, J. A., Baillieul, F., Michaelson, L. V. and Dhondt-Cordelier, S. 2019. Sphingolipids: towards an integrated view of metabolism during the plant stress response. New Phytologist.

The challenges of delivering genetically modified crops with nutritional enhancement traits

A - Papers appearing in refereed journals
Napier, J. A., Haslam, R. P., Tsalavouta, M. and Sayanova, O. V. 2019. The challenges of delivering genetically modified crops with nutritional enhancement traits. Nature Plants. 5, pp. 563-567.

Postprandial incorporation of EPA and DHA from transgenic Camelina sativa oil into blood lipids is equivalent to that from fish oil in healthy humans

A - Papers appearing in refereed journals
West, A. L., Miles, E.A., Lillycrop K. A., Han, L., Sayanova, O. V., Napier, J. A. and Calder, P. C. 2019. Postprandial incorporation of EPA and DHA from transgenic Camelina sativa oil into blood lipids is equivalent to that from fish oil in healthy humans. British Journal Of Nutrition. pp. 1-27.

Update on GM canola crops as novel sources of omega-3 fish oils

A - Papers appearing in refereed journals
Napier, J. A., Olsen, R-E. and Tocher, D. R. 2019. Update on GM canola crops as novel sources of omega-3 fish oils. Plant Biotechnology Journal. 17 (4), pp. 703-705.

Omega-3 Long-Chain Polyunsaturated Fatty Acids, EPA and DHA: Bridging the Gap between Supply and Demand Nutrients

A - Papers appearing in refereed journals
Tocher, D. R., Betancor, M. B., Sprague, M., Olsen, R. E. and Napier, J. A. 2019. Omega-3 Long-Chain Polyunsaturated Fatty Acids, EPA and DHA: Bridging the Gap between Supply and Demand Nutrients . Nutrients. 11 (1), p. 89.

Oat and lipolysis: Food matrix effect

A - Papers appearing in refereed journals
Wilde, P. J., Garcia-Llatas, G., Lagarda, M. J, Haslam, R. P. and Grundy, M. M. L. 2019. Oat and lipolysis: Food matrix effect. Food Chemistry. 278 (25 April), pp. 683-691.

Impact of heat processing on the nutritional content of Gryllus bimaculatus (black cricket)

A - Papers appearing in refereed journals
Dobermann, D., Field, L. M. and Michaelson, L. V. 2019. Impact of heat processing on the nutritional content of Gryllus bimaculatus (black cricket). Nutrition Bulletin. pp. 1-7.

Ectomycorrhizal inoculation with Pisolithus tinctorius reduces stress induced by drought in cork oak

A - Papers appearing in refereed journals
Sebastiana, M., Bernardes da Silva, A, Alcantara, A., Silvestre, S. and Malhó, R. 2018. Ectomycorrhizal inoculation with Pisolithus tinctorius reduces stress induced by drought in cork oak. Mycorrhiza. 28 (3), pp. 247-258.

Transgenic Microalgae With Increased Production Of At Least One Omega-3 Long Chain Polyunsaturated Fatty Acid (Patent US 2018/0312888 A1)

H2 - Patents applied for
Napier, J. A., Sayanova, O. V., Hamilton, M. L. and Vaezi, R. 2018. Transgenic Microalgae With Increased Production Of At Least One Omega-3 Long Chain Polyunsaturated Fatty Acid (Patent US 2018/0312888 A1) . US 2018/0312888 A1

Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent) CA 2744930 C

H2 - Patents applied for
Napier, J. A., Senger, T. and Bauer, J. 2018. Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent) CA 2744930 C. CA 2744930 C

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent CA 2621214 C)

H1 - Patents granted
Napier, J. A. and Sayanova, O. V. 2018. Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent CA 2621214 C). CA 2621214 C

Analysis of Metals in Whole Cells, Thylakoids and Photosynthetic Protein Complexes in Synechocystis sp. PCC6803

A - Papers appearing in refereed journals
Gandini, C., Husted, S. and Schmidt, S. B. 2018. Analysis of Metals in Whole Cells, Thylakoids and Photosynthetic Protein Complexes in Synechocystis sp. PCC6803 . Bio-protocol. 8 (12).

Europe’s first and last field trial of gene-edited plants?

A - Papers appearing in refereed journals
Faure, J-D. and Napier, J. A. 2018. Europe’s first and last field trial of gene-edited plants? eLife. 7 (e42379).

Using Hermetia illucens to process Ugandan waragi waste

A - Papers appearing in refereed journals
Dobermann, D., Field, L. M. and Michaelson, L. V. 2018. Using Hermetia illucens to process Ugandan waragi waste . Journal of Cleaner Production. 211 (20 February), pp. 303-308.

The effect of an initial high-quality feeding regime on the survival of Gryllus bimaculatus (black cricket) on bio-waste

A - Papers appearing in refereed journals
Dobermann, D., Michaelson, L. V. and Field, L. M. 2018. The effect of an initial high-quality feeding regime on the survival of Gryllus bimaculatus (black cricket) on bio-waste. Journal of Insects as Food and Feed. 5 (2), pp. 117-123.

Response of cell wall composition and RNA-seq transcriptome to methyl-jasmonate in Brachypodium distachyon callus

A - Papers appearing in refereed journals
Hyde, L. S., Pellny, T. K., Freeman, J., Michaelson, L. V., Simister, R., McQueen-Mason, S. J. and Mitchell, R. A. C. 2018. Response of cell wall composition and RNA-seq transcriptome to methyl-jasmonate in Brachypodium distachyon callus . Planta. 248 (5), pp. 1213-1229.

Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar)

A - Papers appearing in refereed journals
Betancor, M. B., Li, K., Bucerzan, V. S., Sprague, M., Sayanova, O. V., Usher, S. L., Han, L., Norambuena, F., Torrissen, O., Napier, J. A., Tocher, D. R. and Olsen, R. E. 2018. Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar). British Journal Of Nutrition. 119 (12), pp. 1378-1392.

New insights in the composition of wax and sterol esters in common and mutant sunflower oils revealed by ESI-MS/MS

A - Papers appearing in refereed journals
Broughton, R., Ruíz-Lopez, N., Hassall, K. L., Martínez-Force, E., Garcés, R., Salas, J. J. and Beaudoin, F. 2018. New insights in the composition of wax and sterol esters in common and mutant sunflower oils revealed by ESI-MS/MS. Food Chemistry. 269, pp. 70-79.

Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications

A - Papers appearing in refereed journals
Valegård, K., Andralojc, P. J., Haslam, R. P., Pearce, F. G., Erikson, G. K., Madgwick P. J., Kristoffersen A. K., van Lun, M., Klein, U., Eilertsen H. C., Parry, M. A. J. and Andersson, I. 2018. Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications. Journal of Biological Chemistry.

Overexpression of acetyl-CoA synthetase (ACS) enhances the biosynthesis of neutral lipids and starch in the green microalga Chlamydomonas reinhardtii

A - Papers appearing in refereed journals
Rengel, R., Smith, R. T., Haslam, R. P., Sayanova, O. V., Vila, M. and Leon, R. 2018. Overexpression of acetyl-CoA synthetase (ACS) enhances the biosynthesis of neutral lipids and starch in the green microalga Chlamydomonas reinhardtii. Algal Research-Biomass Biofuels and Bioproducts. 31, pp. 183-193.

Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.)

A - Papers appearing in refereed journals
Haslam, R. P., Cazenave-Gassiot, A., Guschina, I.A., Wenk, M.R., Woodfield, H.K. and Harwood, J.L. 2018. Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.). Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863 (3), pp. 339-348.

Suppression of a single BAHD gene in Setaria viridis causes large, stable decreases in cell wall feruloylation and increases biomass digestibility

A - Papers appearing in refereed journals
De Souza, W. R., Martins, P. K., Freeman, J., Pellny, T. K., Michaelson, L. V., Sampaio, B. L., Vinecky, F., Ribeiro, A. P., Da Cunha, B. A. D. B., Kobayashi, A. K., De Oliveira, P. A., Campanha, R. B., Pacheco, T. F., Martarello, D. C. I., Marchiosi, R., Ferrarese-Filho, O., Dos Santos, W. D., Tramontina, R., Squina, F. M., Centeno, D. C., Gaspar, M., Braga, M. R., Tine, M. A. S., Ralph, J., Mitchell, R. A. C. and Molinari, H. B. C. 2018. Suppression of a single BAHD gene in Setaria viridis causes large, stable decreases in cell wall feruloylation and increases biomass digestibility. New Phytologist. 218 (1), pp. 81-93.

Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent EP 2669380 B1)

H1 - Patents granted
Senger, T., Bauer, J. and Napier, J. A. 2017. Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent EP 2669380 B1) . EP 2669380 B1

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2017/0067070 A1)

H2 - Patents applied for
Bauer, J., Napier, J. A. and Sayanova, O. V. 2017. Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2017/0067070 A1) . US 2017/0067070 A1

Desaturase And Method For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent CA 2723072 C)

H1 - Patents granted
Napier, J. A., Bauer, J. and Sayanova, O. 2017. Desaturase And Method For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent CA 2723072 C). CA 2723072 C

Acyltransferases And Uses Therof In Fatty Acid Production (Patent EP 2585603 B1)

H1 - Patents granted
Senger, T., Marty, L., Stymne, S., Lindberg , Y. J., Napier, J. A., Sayanova, O. V., Haslam, R. P. and Ruiz-Lopez, N. 2017. Acyltransferases And Uses Therof In Fatty Acid Production (Patent EP 2585603 B1). EP 2585603 B1

Process For Producing A Polyunsatured Fatty Acid Comprising Arachidonic Acid (Patent EP 2380984 B1)

H1 - Patents granted
Napier, J. A., Sayanova, O. V. and Venegas Caleron, M. 2017. Process For Producing A Polyunsatured Fatty Acid Comprising Arachidonic Acid (Patent EP 2380984 B1). EP 2380984 B1

An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry

A - Papers appearing in refereed journals
Betancor, M. B., Li, K., Sprague, M., Bardal, T., Sayanova, O. V., Usher, S., Han, L., Måsøval, K., Torrissen, O., Napier, J. A., Tocher, D. R. and Olsen, R. E. 2017. An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry. PLOS ONE. 12 (4), p. e0175415.

Effects of Cultivar and Nitrogen Nutrition on the Lipid Composition of Wheat Flour

A - Papers appearing in refereed journals
Min, B., Gonzalez-Thuillier, I., Powers, S. J., Wilde, P. J., Shewry, P. R. and Haslam, R. P. 2017. Effects of Cultivar and Nitrogen Nutrition on the Lipid Composition of Wheat Flour. Journal of Agricultural and Food Chemistry - JAFC. 65 (26), pp. 5427-5434.

Intrinsic wheat lipid composition effects the interfacial and foaming properties of dough liquor

A - Papers appearing in refereed journals
Salt, L. J., Gonzalez-Thuillier, I., Chope, G., Penson, S., Tosi, P., Haslam, R. P., Skeggs, P. K., Shewry, P. R. and Wilde, P. J. 2017. Intrinsic wheat lipid composition effects the interfacial and foaming properties of dough liquor. Food Hydrocolloids. 75 (17 August), pp. 211-222.

A Palmitic Acid Elongase Affects Eicosapentaenoic Acid and Plastidial Monogalactosyldiacylglycerol Levels in Nannochloropsis

A - Papers appearing in refereed journals
Dolch, L-J., Rak, C., Perin, G., Tourcier, G., Broughton, R., Leterrier, M., Morosinotto, T., Tellier, F., Faure, J-D., Falconet, D., Jouhet, J., Sayanova, O. V., Beaudoin, F. and Maréchal, E. 2017. A Palmitic Acid Elongase Affects Eicosapentaenoic Acid and Plastidial Monogalactosyldiacylglycerol Levels in Nannochloropsis. Plant Physiology. 173 (1), pp. 742-759.

Lipid remodelling: Unravelling the response to cold stress in Arabidopsis and its extremophile relative Eutrema salsugineum

A - Papers appearing in refereed journals
Barrero-Sicilia, C., Silvestre, S., Haslam, R. P. and Michaelson, L. V. 2017. Lipid remodelling: Unravelling the response to cold stress in Arabidopsis and its extremophile relative Eutrema salsugineum. Plant Science. 263 (October), pp. 194-200.

Tailoring seed oil composition in the real world: optimising omega -3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa

A - Papers appearing in refereed journals
Usher, S. L., Han, L., Haslam, R. P., Michaelson, L. V., Sturtevant, D., Aziz, M., Chapman, K. D., Sayanova, O. V. and Napier, J. A. 2017. Tailoring seed oil composition in the real world: optimising omega -3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa. Scientific Reports. 7 (1), p. 6570.

0 total views
0 total downloads
0 views this month
0 downloads this month