An overview of functional genomic tools in deciphering insecticide resistance

A - Papers appearing in refereed journals

Homem, R. A. and Davies, T. G. E. 2018. An overview of functional genomic tools in deciphering insecticide resistance. Current Opinion in Insect Science. 27 (June), pp. 103-110.

AuthorsHomem, R. A. and Davies, T. G. E.

In this short review, we highlight three functional genomic technologies that have recently been contributing to the understanding of the molecular mechanisms underpinning insecticide resistance: the GAL4/UAS system, a molecular tool used to express genes of interest in a spatiotemporal controlled manner; the RNAi system, which is used to knock-down gene expression; and the most recently developed gene editing tool,CRISPR/Cas9, which can be used to knock-out and knock-in sequences of interest.

Year of Publication2018
JournalCurrent Opinion in Insect Science
Journal citation27 (June), pp. 103-110
Digital Object Identifier (DOI)
PubMed ID30025625
PubMed Central IDPMC6060081
Open accessPublished as ‘gold’ (paid) open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeBBSRC Strategic Programme in Smart Crop Protection
Publisher's version
Output statusPublished
Publication dates
Online13 Apr 2018
PublisherElsevier Science Bv
Copyright licenseCC BY

Permalink -

116 total views
125 total downloads
3 views this month
3 downloads this month
Download files as zip