Hidden variation in polyploid wheat drives local adaptation

A - Papers appearing in refereed journals

Gardiner, L.-J., Joynson, R., Omony, J., Rusholme-Pilcher, R., Olohan, L., Lang, D., Bai, C., Hawkesford, M. J., Salt, D., Spannagl, M., Mayer, K. F. X., Kenny, J., Bevan, M., Hall, N. and Hall, A. 2018. Hidden variation in polyploid wheat drives local adaptation. Genome Research. 28, pp. 1-14.

AuthorsGardiner, L.-J., Joynson, R., Omony, J., Rusholme-Pilcher, R., Olohan, L., Lang, D., Bai, C., Hawkesford, M. J., Salt, D., Spannagl, M., Mayer, K. F. X., Kenny, J., Bevan, M., Hall, N. and Hall, A.
Abstract

Wheat has been domesticated into a large number of agricultural environments and has the ability to adapt to diverse environments. To understand this process, we survey genotype, repeat content, and DNA methylation across a bread wheat landrace collection representing global genetic diversity. We identify independent variation in methylation, genotype, and transposon copy number. We show that these, so far unexploited, sources of variation have had a significant impact on the wheat genome and that ancestral methylation states become preferentially “hard coded” as single nucleotide polymorphisms (SNPs) via 5-methylcytosine deamination. These mechanisms also drive local adaption, impacting important traits such as heading date and salt tolerance. Methylation and transposon diversity could therefore be used alongside SNP-based markers for breeding.

Year of Publication2018
JournalGenome Research
Journal citation28, pp. 1-14
Digital Object Identifier (DOI)doi:10.1101/gr.233551.117
Open accessPublished as green open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeDesigning Future Wheat (DFW) [ISPG]
DFW - Designing Future Wheat - Work package 1 (WP1) - Increased efficiency and sustainability
Publisher's version
Output statusPublished
Publication dates
Online09 Aug 2018
Publication process dates
Accepted16 Jul 2018
PublisherCold Spring Harbor Lab Press, Publications Dept
Copyright licenseCC BY
ISSN1088-9051

Permalink - https://repository.rothamsted.ac.uk/item/84853/hidden-variation-in-polyploid-wheat-drives-local-adaptation

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