Dissecting the molecular interactions between wheat and the fungal pathogen Zymoseptoria tritici

A - Papers appearing in refereed journals

Kettles, G. J. and Kanyuka, K. 2016. Dissecting the molecular interactions between wheat and the fungal pathogen Zymoseptoria tritici. Frontiers in Plant Science. 7, p. 508.

AuthorsKettles, G. J. and Kanyuka, K.
Abstract

The Dothideomycete fungus Zymoseptoria tritici (previously known as Mycosphaerella graminicola and Septoria tritici) is the causative agent of Septoria tritici leaf blotch (STB) disease of wheat (Triticum aestivum L.). In Europe, STB is the most economically damaging disease of wheat, with an estimated ∼€1 billion per year in fungicide expenditure directed toward its control. Here, an overview of our current understanding of the molecular events that occur during Z. tritici infection of wheat leaves is presented. On the host side, this includes the contribution of (1) the pathogen-associated molecular pattern-triggered immunity (PTI) layer of plant defense, and (2) major Stb loci for resistance against Z. tritici. On the pathogen side of the interaction, we consolidate evidence from recent bioinformatic, transcriptomic and proteomic studies that begin to explain the contribution of Z. tritici effector proteins to the biphasic lifestyle of the fungus. This includes the discovery of chitin-binding proteins in the Z. tritici secretome, which contribute to evasion of immune surveillance by this pathogen, and the possible existence of ‘necrotrophic’ effectors from Z. tritici, which may actively stimulate host recognition in a manner similar to related necrotrophic fungal pathogens. We finish by speculating on how some of these recent fundamental discoveries might be harnessed to help improve resistance to STB in the world’s second largest food crop.

KeywordsSeptoria tritici blotch (STB); Mycosphaerella graminicola; effector; pathogen-associated molecular pattern (PAMP); chitin; disease resistance; PAMP-triggered immunity (PTI); wheat
Year of Publication2016
JournalFrontiers in Plant Science
Journal citation7, p. 508
Digital Object Identifier (DOI)doi:10.3389/fpls.2016.00508
Open accessPublished as ‘gold’ (paid) open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or codeWheat
IDG/Identifying cell death-inducing effectors and host targets in the interaction of wheat leaves with the fungal pathogen Zymoseptoria tritici (Mycosphaerella graminicola)
[20:20 Wheat] Protecting yield potential of wheat
Publisher's version
Output statusPublished
Publication dates
Online15 Apr 2016
Publication process dates
Accepted30 Mar 2016
Copyright licenseCC BY
PublisherFrontiers Media SA
ISSN1664-462X

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