Shifting the limits in wheat research and breeding using a fully annotated reference genome

A - Papers appearing in refereed journals

International Wheat Genome Sequencing Consortium (IWGSC), Kanyuka, K. and King, R. 2018. Shifting the limits in wheat research and breeding using a fully annotated reference genome. Science. 361 (6403), p. eaar7191.

AuthorsInternational Wheat Genome Sequencing Consortium (IWGSC), Kanyuka, K. and King, R.
Abstract

An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic 10 context of coding and non-coding elements across the A, B and D sub-genomes. With an estimated coverage of 94% of the genome and containing 107,891 high confidence gene models, this assembly enabled the discovery of tissue and developmental stage related co-expression networks using a transcriptome atlas representing all stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at 15 sub-genome resolution and contextualized to known agronomic single gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.

KeywordsWheat; Genome; Annotation; Gene families
Year of Publication2018
JournalScience
Journal citation361 (6403), p. eaar7191
Digital Object Identifier (DOI)doi:10.1126/science.aar7191
Open accessPublished as ‘gold’ (paid) open access
FunderBiotechnology and Biological Sciences Research Council
Funder project or code[20:20 Wheat] Protecting yield potential of wheat
DFW - Designing Future Wheat - Work package 2 (WP2) - Added value and resilience
Output statusPublished
Publication dates
Online17 Aug 2018
Publication process dates
Accepted11 Jul 2018
PublisherAmerican Association for the Advancement of Science (AAAS)
Copyright licenseCC BY
ISSN0036-8075
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Permalink - https://repository.rothamsted.ac.uk/item/84751/shifting-the-limits-in-wheat-research-and-breeding-using-a-fully-annotated-reference-genome

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