Elongase Gene And Production Of Delta9-polyunsaturated Fatty Acids (Patent US 7601889 B2)

UNSPECIFIED (2009) Elongase Gene And Production Of Delta9-polyunsaturated Fatty Acids (Patent US 7601889 B2). US 7601889 B2.
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This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use. The inventive nucleic acid sequence encodes a polypeptide which elongates alpha-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas gamma-linolenic acid (C18:3 d6, 9, 12) is not elongated. The invention additionally relates to vectors or organisms comprising an elongase gene having the sequence SEQ ID NO: 1 or its derivatives. The invention further relates to a process for the production of polyunsaturated fatty acids (=PUFAs) with an organism which comprises the elongase gene and which organism produces high amounts of oils and especially oils with a high content of unsaturated fatty acids. Additionally the invention relates to an oil and/or fatty acid composition with a higher content of polyunsaturated C20 or C22 fatty acids with at least two double bonds and/or to a triacylglycerol composition with a higher content of said polyunsaturated fatty acids.


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