Synthetic redesign of plant lipid metabolism

A - Papers appearing in refereed journals

Haslam, R. P., Sayanova, O. V., Kim, H. J., Cahoon, E. B. and Napier, J. A. 2016. Synthetic redesign of plant lipid metabolism. The Plant Journal. 87 (1), pp. 76-86.

AuthorsHaslam, R. P., Sayanova, O. V., Kim, H. J., Cahoon, E. B. and Napier, J. A.
Abstract

Plant seed lipid metabolism is an area of intensive research, including many examples of transgenic events in which oil composition has been modified. In the selected examples described in this review, progress towards the predictive manipulation of metabolism and the reconstitution of desired traits in a non-native host is considered. The advantages of a particular oilseed crop, Camelina sativa, as a flexible and utilitarian chassis for advanced metabolic engineering and applied synthetic biology are considered, as are the issues that still represent gaps in our ability to predictably alter plant lipid biosynthesis. Opportunities to deliver useful bio-based products via transgenic plants are described, some of which represent the most complex genetic engineering in plants to date. Future prospects are considered, with a focus on the desire to transition to more (computationally) directed manipulations of metabolism.

KeywordsPlant Sciences
Year of Publication2016
JournalThe Plant Journal
Journal citation87 (1), pp. 76-86
Digital Object Identifier (DOI)doi:10.1111/tpj.13172
PubMed ID27483205
Open accessPublished as ‘gold’ (paid) open access
Funder project or codeDesigning Seeds for Nutrition and Health (DS)
*Design Oilseeds (Olga Sayanova)
Designing oilseeds for nutrition and health
IOS-13-39385
FunderBiotechnology and Biological Sciences Research Council
Nebraska Centre for Energy Science Research
National Science Foundation - US
PublisherWiley
Wiley-Blackwell
ISSN0960-7412

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