A - Papers appearing in refereed journals
Haslam, R. P., Sayanova, O. V., Kim, H. J., Cahoon, E. B. and Napier, J. A. 2016. Synthetic redesign of plant lipid metabolism. The Plant Journal. 87 (1), pp. 76-86.
|Authors||Haslam, R. P., Sayanova, O. V., Kim, H. J., Cahoon, E. B. and Napier, J. A.|
Plant seed lipid metabolism is an area of intensive research, including many examples of transgenic events in which oil composition has been modified. In the selected examples described in this review, progress towards the predictive manipulation of metabolism and the reconstitution of desired traits in a non-native host is considered. The advantages of a particular oilseed crop, Camelina sativa, as a flexible and utilitarian chassis for advanced metabolic engineering and applied synthetic biology are considered, as are the issues that still represent gaps in our ability to predictably alter plant lipid biosynthesis. Opportunities to deliver useful bio-based products via transgenic plants are described, some of which represent the most complex genetic engineering in plants to date. Future prospects are considered, with a focus on the desire to transition to more (computationally) directed manipulations of metabolism.
|Year of Publication||2016|
|Journal||The Plant Journal|
|Journal citation||87 (1), pp. 76-86|
|Digital Object Identifier (DOI)||doi:10.1111/tpj.13172|
|Open access||Published as ‘gold’ (paid) open access|
|Funder project or code||Designing Seeds for Nutrition and Health (DS)|
|*Design Oilseeds (Olga Sayanova)|
|Designing oilseeds for nutrition and health|
|Funder||Biotechnology and Biological Sciences Research Council|
|Nebraska Centre for Energy Science Research|
|National Science Foundation - US|
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