Dissection and manipulation of metabolic signalling pathways

A - Papers appearing in refereed journals

Halford, N. G., Hey, S., Jhurreea, D., Laurie, S., Mckibbin, R. S., Zhang, Y. and Paul, M. J. 2003. Dissection and manipulation of metabolic signalling pathways. Annals of Applied Biology - AAB. 142 (1), pp. 25-31. https://doi.org/10.1111/j.1744-7348.2003.tb00225.x

AuthorsHalford, N. G., Hey, S., Jhurreea, D., Laurie, S., Mckibbin, R. S., Zhang, Y. and Paul, M. J.

The partitioning of resources between different plant organs and compounds is an important determinant of crop quality. We are attempting to change resource partitioning in crop plants by manipulating the cellular mechanisms involved in metabolite sensing and signalling. One of the proteins involved is SnRK1 (sucrose nonfermenting-1-related protein kinase 1), so-called because of its homology and functional similarity with sucrose non-fermenting 1 (SNF1) of yeast. SnRK1 is a protein kinase that plays a key role in the global control of plant carbon metabolism. Here we review studies on the characterisation of SnRK1 gene families, SnRK1 regulation and function, and the identification of SnRK1-interacting proteins. We also describe some potential applications of manipulating SnRK1 activity, including controlling sprouting in stored potato tubers, inducing male sterility in barley and increasing sterol levels in oilseeds.

KeywordsAgriculture, Multidisciplinary
Year of Publication2003
JournalAnnals of Applied Biology - AAB
Journal citation142 (1), pp. 25-31
Digital Object Identifier (DOI)https://doi.org/10.1111/j.1744-7348.2003.tb00225.x
Open accessPublished as non-open access
Funder project or code414
Project: 4150
Project: 4047
Project: 4230
Project: 4508

Permalink - https://repository.rothamsted.ac.uk/item/891z4/dissection-and-manipulation-of-metabolic-signalling-pathways

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